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This paper contributes to the HCI literature on usability practice with insights about the empirical challenges and global emerging practices caused by the advent of agile software development (ASD). In the paper we report from a worldwide study involving 12 usability professionals from 12 different countries. The findings show that the usability professionals share a forced development and innovation in their practice that stem from their clients' adoption and use of ASD methods. The ASD methods challenge the way usability testing is performed, the abilities of the usability expert, the usability deliverables, and the experts' assumptions about the importance of validity.