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The anisotropic minimum-dissipation (AMD) model for large-eddy simulation (LES) has been recently developed, and here the model performance is examined in stratified plane Couette flow. To our knowledge, this is the first use of the AMD model for resolved LES of stratified wall-bounded flow. A comparison with previously published direct numerical simulations (DNS) provides insight into model and grid requirements. Prandtl numbers of Pr= 0.7–70 and a range of Richardson numbers show that the AMD LES performs well even with a strong stabilising buoyancy flux. We identify three new requirements for accurate LES of stratified wall-bounded flow. First, the LES must resolve the turbulent structures at the edge of the viscous sublayer in order to satisfy the Obukov length scale condition, L s+> 200⁠. Otherwise the LES solution may laminarise where the DNS solution remains turbulent. Second, the LES must …