Authors
Michael Matschiner, Walter Salzburger
Publication date
2009/8/1
Journal
Bioinformatics
Volume
25
Issue
15
Pages
1982-1983
Publisher
Oxford University Press
Description
Summary: Computer programs for the statistical analysis of microsatellite data use allele length variation to infer, e.g. population genetic parameters, to detect quantitative trait loci or selective sweeps. However, observed allele lengths are usually inaccurate and may deviate from the expected periodicity of repeats. The common practice of rounding to the nearest whole number frequently results in miscalls and underestimations of allelic richness. Manual sorting of allele lengths into discrete classes, a process called binning, is tedious and error-prone. Here, we present a new program for the automated binning of microsatellite allele lengths to overcome these problems and to facilitate high-throughput allele binning.
Availability:  www.evolution.unibas.ch/salzburger/software.htm
Contact:  [email protected]
Supplementary information …
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