Authors
David J Beebe, Jeffrey S Moore, Joseph M Bauer, Qing Yu, Robin H Liu, Chelladurai Devadoss, Byung-Ho Jo
Publication date
2000/4/6
Journal
nature
Volume
404
Issue
6778
Pages
588-590
Publisher
Nature Publishing Group UK
Description
Hydrogels have been developed to respond to a wide variety of stimuli,,,,,, but their use in macroscopic systems has been hindered by slow response times (diffusion being the rate-limiting factor governing the swelling process). However, there are many natural examples of chemically driven actuation that rely on short diffusion paths to produce a rapid response. It is therefore expected that scaling down hydrogel objects to the micrometre scale should greatly improve response times. At these scales, stimuli-responsive hydrogels could enhance the capabilities of microfluidic systems by allowing self-regulated flow control. Here we report the fabrication of active hydrogel components inside microchannels via direct photopatterning of a liquid phase. Our approach greatly simplifies system construction and assembly as the functional components are fabricated in situ, and the stimuli-responsive hydrogel components …
Total citations
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