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Efforts characterizing the changing climate of southwestern North America by focusing exclusively on the impacts of increasing levels of long-lived greenhouse gases omit fundamental elements with similar order-of-magnitude impacts as those owing to large-scale climate change^,. Using a suite of ensemble-based, multiyear simulations, here we show the intensification of observationally based urban-induced phenomena and demonstrate that the direct summer-time climate effects of the most rapidly expanding megapolitan region in the USA—Arizona’s Sun Corridor—are considerable. Although urban-induced warming approaches 4 °C locally for the maximum expansion scenario, impacts depend on the particular trajectory of development. Cool-roof implementation reduces simulated warming by about 50%, yet decreases in summer-time evapotranspiration remain at least as large as those from urban …