Authors
Tanja Kraus, Frank Moszner, Stefan Fischerauer, Michael Fiedler, Elisabeth Martinelli, Johannes Eichler, Frank Witte, Elmar Willbold, Michael Schinhammer, Martin Meischel, Peter J Uggowitzer, Jörg F Löffler, Annelie Weinberg
Publication date
2014/7/1
Journal
Acta biomaterialia
Volume
10
Issue
7
Pages
3346-3353
Publisher
Elsevier
Description
This study investigates the degradation performance of three Fe-based materials in a growing rat skeleton over a period of 1 year. Pins of pure Fe and two Fe-based alloys (Fe–10Mn–1Pd and Fe–21Mn–0.7C–1Pd, in wt.%) were implanted transcortically into the femur of 38 Sprague–Dawley rats and inspected after 4, 12, 24 and 52 weeks. The assessment was performed by ex vivo microfocus computed tomography, weight-loss determination, surface analysis of the explanted pins and histological examination. The materials investigated showed signs of degradation; however, the degradation proceeded rather slowly and no significant differences between the materials were detected. We discuss these unexpected findings on the basis of fundamental considerations regarding iron corrosion. Dense layers of degradation products were formed on the implants’ surfaces, and act as barriers against oxygen transport …
Total citations
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