Authors
Samuel T Chao, Taisei Kobayashi, Edward Benzel, Chandana A Reddy, Glen HJ Stevens, Richard A Prayson, Iain Kalfas, Richard Schlenk, Ajit Krishnaney, Michael P Steinmetz, William Bingaman, Joseph Hahn, John H Suh
Publication date
2011/1/1
Journal
Journal of Neurosurgery: Spine
Volume
14
Issue
1
Pages
59-64
Publisher
American Association of Neurological Surgeons
Description
Object
The goal in this study was to determine the role of radiation therapy (RT) in the treatment of spinal myxopapillary ependymomas (MPEs).
Methods
Thirty-seven patients with histologically verified spinal MPEs were reviewed. Kaplan-Meier analyses and Cox proportional hazard regression were used to determine what patient and treatment factors influenced overall survival (OS) and recurrence.
Results
At the time of initial diagnosis, the median age was 33 years and the Karnofsky Performance Scale score was 80. In 86.5% of cases, the most common presenting symptom was pain. All patients received surgery as their initial treatment. Nine patients also received RT along with surgery, with a median total dose of 50.2 Gy. The mean survival time was 12.2 years; however, only 4 of 37 patients had died at the time of this study. None of the patient …
Total citations
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