Authors
DC Neujahr, A Pelaez, A Ramirez, SD Force, EC Lawrence, AC Cardona, AD Kirk, CP Larsen
Publication date
2009/2/1
Journal
The Journal of Heart and Lung Transplantation
Volume
28
Issue
2
Pages
S224
Publisher
Elsevier
Description
Purpose
Gastroesophageal reflux (GERD) is associated with graft failure after lung transplant. It is proposed that GERD results in an innate immunologic danger stimulus which triggers subsequent alloimmune responses in the lung. We predicted that surgical correction of GERD would be associated with a decrease in the activation state of T cells recovered in the lungs.
Scholar articles
DC Neujahr, A Pelaez, A Ramirez, SD Force… - The Journal of Heart and Lung Transplantation, 2009