Authors
Anas Alfarsi, Céline Caillet, Garry Fawbert, Simon Lawrence, Jacob Krüse, Seán McSweeney, Marcus O’Mahony, Arjen Dondorp, Paul N Newton, Dara Fitzpatrick
Publication date
2021/6/16
Journal
Scientific Reports
Volume
11
Issue
1
Pages
12643
Publisher
Nature Publishing Group UK
Description
The trade in falsified medicine has increased significantly and it is estimated that global falsified sales have reached $100 billion in 2020. The EU Falsified Medicines Directive states that falsified medicines do not only reach patients through illegal routes but also via the legal supply chain. Falsified medicines can contain harmful ingredients. They can also contain too little or too much active ingredient or no active ingredient at all. BARDS (Broadband Acoustic Resonance Dissolution Spectroscopy) harnesses an acoustic phenomenon associated with the dissolution of a sample (tablet or powder). The resulting acoustic spectrum is unique and intrinsic to the sample and can be used as an identifier or signature profile. BARDS was evaluated in this study to determine whether a product is falsified or genuine in a rapid manner and at lower cost than many existing technologies. A range of genuine and falsified …
Total citations
2021202233