Authors
Firouz M Moghaddam, Ghasem R Bardajee, Seyedeh Taimoory
Publication date
2006/2/1
Journal
Letters in Organic Chemistry
Volume
3
Issue
2
Pages
157-160
Publisher
Bentham Science Publishers
Description
KF/Al2O3 efficiently catalyzes aza-Michael addition of indole and 3-methylindole to a variety of electron-deficient conjugated alkenes such as α,β-unsaturated ketones, amides and nitriles. The N-alkylation adducts are produced in good to excellent yields and relatively in short times. The catalyst can be recycled for subsequent reactions without any appreciable loss of efficiency.
Total citations
Scholar articles
FM Moghaddam, GR Bardajee, S Taimoory - Letters in Organic Chemistry, 2006