| A first-in-class, highly selective and cell-active allosteric inhibitor of protein arginine methyltransferase 6 Y Shen, F Li, MM Szewczyk, L Halabelian, I Chau, MS Eram, C Dela Sena, ... Journal of medicinal chemistry 64 (7), 3697-3706, 2021 | 20 | 2021 |
| Normalizing molecular docking rankings using virtually generated decoys I Wallach, N Jaitly, K Nguyen, M Schapira, R Lilien Journal of chemical information and modeling 51 (8), 1817-1830, 2011 | 19 | 2011 |
| Evaluation of virtual screening as a tool for chemical genetic applications V Campagna-Slater, M Schapira Journal of chemical information and modeling 49 (9), 2082-2091, 2009 | 16 | 2009 |
| Crystal structures of Klebsiella pneumoniae pantothenate kinase in complex with N‐substituted pantothenamides B Li, W Tempel, D Smil, Y Bolshan, M Schapira, HW Park Proteins: Structure, Function, and Bioinformatics 81 (8), 1466-1472, 2013 | 15 | 2013 |
| Pharmacogenomics opportunities in nuclear receptor targeted cancer therapy M Schapira Current cancer drug targets 2 (3), 243-256, 2002 | 15 | 2002 |
| Building skeletally diverse architectures on the Indoline Scaffold: The discovery of a chemical probe of focal adhesion kinase signaling networks M Prakesch, K Bijian, V Campagna-Slater, S Quevillon, R Joseph, ... Bioorganic & medicinal chemistry 16 (21), 9596-9602, 2008 | 14 | 2008 |
| Identification of 12Cysβ on tubulin as the binding site of tubulyzine YJ Kim, DL Sackett, M Schapira, DP Walsh, J Min, LK Pannell, YT Chang Bioorganic & medicinal chemistry 14 (4), 1169-1175, 2006 | 14 | 2006 |
| I-Sce III: a novel group I intron-encoded endonuclease from the yeast mitochondria. J Perea, C Desdouets, M Schapira, C Jacq Nucleic acids research 21 (2), 358, 1993 | 14 | 1993 |
| Discovery of small molecule antagonists of the USP5 zinc finger ubiquitin-binding domain MK Mann, I Franzoni, RF de Freitas, W Tempel, S Houliston, L Smith, ... Journal of medicinal chemistry 62 (22), 10144-10155, 2019 | 13 | 2019 |
| Identification and characterization of the first fragment hits for SETDB1 Tudor domain P Mader, R Mendoza-Sanchez, A Iqbal, A Dong, E Dobrovetsky, ... Bioorganic & Medicinal Chemistry 27 (17), 3866-3878, 2019 | 13 | 2019 |
| Selective, small-molecule co-factor binding site inhibition of a Su (var) 3–9, enhancer of zeste, trithorax domain containing lysine methyltransferase AP Taylor, M Swewczyk, S Kennedy, VV Trush, H Wu, H Zeng, A Dong, ... Journal of medicinal chemistry 62 (17), 7669-7683, 2019 | 13 | 2019 |
| ChromoHub V2: cancer genomics MA Shah, EL Denton, L Liu, M Schapira Bioinformatics 30 (4), 590-592, 2014 | 13 | 2014 |
| Structure–Activity Relationship of USP5 Inhibitors MK Mann, CA Zepeda-Velázquez, H González-Álvarez, A Dong, T Kiyota, ... Journal of medicinal chemistry 64 (20), 15017-15036, 2021 | 11 | 2021 |
| A novel allosteric modulator of the cannabinoid CB1 receptor ameliorates hyperdopaminergia endophenotypes in rodent models CA Mielnik, KS Sugamori, DB Finlay, HHA Thorpe, M Schapira, ... Neuropsychopharmacology 46 (2), 413-422, 2021 | 11 | 2021 |
| Identification of Small Molecule Inhibitors That Block the Toxoplasma gondii Rhoptry Kinase ROP18 C Simpson, NG Jones, EA Hull-Ryde, D Kireev, M Stashko, K Tang, ... ACS infectious diseases 2 (3), 194-206, 2016 | 11 | 2016 |
| Structural genomics of histone tail recognition M Wang, MW Mok, H Harper, WH Lee, J Min, S Knapp, U Oppermann, ... Bioinformatics 26 (20), 2629-2630, 2010 | 11 | 2010 |
| Discovery of a novel DCAF1 ligand using a drug–target interaction prediction model: generalizing machine learning to new drug targets SW Kimani, J Owen, SR Green, F Li, Y Li, A Dong, PJ Brown, S Ackloo, ... Journal of Chemical Information and Modeling 63 (13), 4070-4078, 2023 | 10 | 2023 |
| Structural diversity of the epigenetics pocketome A Cabaye, KT Nguyen, L Liu, V Pande, M Schapira Proteins: Structure, Function, and Bioinformatics 83 (7), 1316-1326, 2015 | 10 | 2015 |
| RAS and PP2A activities converge on epigenetic gene regulation A Aakula, M Sharma, F Tabaro, R Nätkin, J Kamila, H Honkanen, ... Life science alliance 6 (5), 2023 | 8 | 2023 |
| Illuminating the druggable genome through patent bioactivity data MP Magariños, A Gaulton, E Félix, T Kiziloren, R Arcila, TI Oprea, ... PeerJ 11, e15153, 2023 | 7 | 2023 |
