Public access

EWS/FLI confers tumor cell synthetic lethality to CDK12 inhibition in Ewing sarcoma

AB Iniguez, B Stolte, EJ Wang, AS Conway, G Alexe, NV Dharia, ...

Cancer cell 33 (2), 202-216. e6, 2018

Mandates: US National Institutes of Health, Damon Runyon Cancer Research Foundation

MeCP2 links heterochromatin condensates and neurodevelopmental disease

CH Li, EL Coffey, A Dall’Agnese, NM Hannett, X Tang, JE Henninger, ...

Nature 586 (7829), 440-444, 2020

Mandates: US National Science Foundation, US National Institutes of Health

[PDF] springer.com

Ligand-dependent dynamics of retinoic acid receptor binding during early neurogenesis

S Mahony, EO Mazzoni, S McCuine, RA Young, H Wichterle, DK Gifford

Genome biology 12, 1-15, 2011

Mandates: US National Institutes of Health

[HTML] cshlp.org

MYC and transcription elongation

PB Rahl, RA Young

Cold Spring Harbor perspectives in medicine 4 (1), a020990, 2014

Mandates: US National Institutes of Health

[HTML] cshlp.org

Ronin/Hcf-1 binds to a hyperconserved enhancer element and regulates genes involved in the growth of embryonic stem cells

M Dejosez, SS Levine, GM Frampton, WA Whyte, SA Stratton, MC Barton, ...

Genes & development 24 (14), 1479-1484, 2010

Mandates: US National Institutes of Health

Cross-cohort analysis identifies a TEAD4–MYCN positive feedback loop as the core regulatory element of high-risk neuroblastoma

P Rajbhandari, G Lopez, C Capdevila, B Salvatori, J Yu, ...

Cancer discovery 8 (5), 582-599, 2018

Mandates: US National Institutes of Health

Multiple structural maintenance of chromosome complexes at transcriptional regulatory elements

JM Dowen, S Bilodeau, DA Orlando, MR Hübner, BJ Abraham, ...

Stem cell reports 1 (5), 371-378, 2013

Mandates: US National Institutes of Health, Canadian Institutes of Health Research

lncRNA DIGIT and BRD3 protein form phase-separated condensates to regulate endoderm differentiation

K Daneshvar, MB Ardehali, IA Klein, FK Hsieh, AJ Kratkiewicz, A Mahpour, ...

Nature cell biology 22 (10), 1211-1222, 2020

Mandates: US National Institutes of Health

Suppression of adaptive responses to targeted cancer therapy by transcriptional repression

M Rusan, K Li, Y Li, CL Christensen, BJ Abraham, N Kwiatkowski, ...

Cancer discovery 8 (1), 59-73, 2018

Mandates: US National Institutes of Health

BORIS promotes chromatin regulatory interactions in treatment-resistant cancer cells

DN Debruyne, R Dries, S Sengupta, D Seruggia, Y Gao, B Sharma, ...

Nature 572 (7771), 676-680, 2019

Mandates: US National Institutes of Health

Nanog-like regulates endoderm formation through the Mxtx2-Nodal pathway

C Xu, ZP Fan, P Müller, R Fogley, A DiBiase, E Trompouki, ...

Developmental cell 22 (3), 625-638, 2012

Mandates: US National Institutes of Health, Howard Hughes Medical Institute

[HTML] cell.com

The Msx1 homeoprotein recruits polycomb to the nuclear periphery during development

J Wang, RM Kumar, VJ Biggs, H Lee, Y Chen, MH Kagey, RA Young, ...

Developmental cell 21 (3), 575-588, 2011

Mandates: US National Institutes of Health

[HTML] cshlp.org

The rate of protein synthesis in hematopoietic stem cells is limited partly by 4E-BPs

RAJ Signer, L Qi, Z Zhao, D Thompson, AA Sigova, ZP Fan, ...

Genes & development 30 (15), 1698-1703, 2016

Mandates: US National Institutes of Health, Howard Hughes Medical Institute

[PDF] nature.com

Small genomic insertions form enhancers that misregulate oncogenes

BJ Abraham, D Hnisz, AS Weintraub, N Kwiatkowski, CH Li, Z Li, ...

Nature communications 8 (1), 14385, 2017

Mandates: US National Institutes of Health, Austrian Science Fund, National Natural …

[HTML] cell.com

Cdk1 controls global epigenetic landscape in embryonic stem cells

W Michowski, JM Chick, C Chu, A Kolodziejczyk, Y Wang, JM Suski, ...

Molecular cell 78 (3), 459-476. e13, 2020

Mandates: US National Institutes of Health

Ten years of genetics and genomics: what have we achieved and where are we heading?

E Heard, S Tishkoff, JA Todd, M Vidal, GP Wagner, J Wang, D Weigel, ...

Nature Reviews Genetics 11 (10), 723-733, 2010

Mandates: US National Institutes of Health

Embryonic stem cell–based mapping of developmental transcriptional programs

EO Mazzoni, S Mahony, M Iacovino, CA Morrison, G Mountoufaris, ...

Nature methods 8 (12), 1056-1058, 2011

Mandates: US National Institutes of Health

[HTML] sciencedirect.com

Activation of the LMO2 oncogene through a somatically acquired neomorphic promoter in T-cell acute lymphoblastic leukemia

S Rahman, M Magnussen, TE León, N Farah, Z Li, BJ Abraham, KZ Alapi, ...

Blood, The Journal of the American Society of Hematology 129 (24), 3221-3226, 2017

Mandates: US National Institutes of Health, Blood Cancer UK, Cancer Research UK, UK …

Stress from nucleotide depletion activates the transcriptional regulator HEXIM1 to suppress melanoma

JL Tan, RD Fogley, RA Flynn, J Ablain, S Yang, V Saint-André, ZP Fan, ...

Molecular cell 62 (1), 34-46, 2016

Mandates: US National Institutes of Health, Howard Hughes Medical Institute, A*Star …

[PDF] biorxiv.org