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Multi-method genome-and epigenome-wide studies of inflammatory protein levels in healthy older adults

RF Hillary, D Trejo-Banos, A Kousathanas, DL McCartney, SE Harris, ...

Genome medicine 12, 1-15, 2020

Mandates: US National Institutes of Health, Australian Research Council, National …

Exploratory analysis of age and sex dependent DNA methylation patterns on the X-chromosome in whole blood samples

S Li, JB Lund, K Christensen, J Baumbach, J Mengel-From, T Kruse, W Li, ...

Genome Medicine 12, 1-13, 2020

Mandates: UK Biotechnology and Biological Sciences Research Council, UK Economic and …

Epigenetic prediction of complex traits and mortality in a cohort of individuals with oropharyngeal cancer

RJ Langdon, RA Beynon, K Ingarfield, RE Marioni, DL McCartney, ...

Clinical epigenetics 12, 1-14, 2020

Mandates: Cancer Research UK, UK Medical Research Council, National Institute for …

[PDF] sdu.dk

Weighted Gene Coregulation Network Analysis of Promoter DNA Methylation on All-Cause Mortality in Old-Aged Birth Cohorts Finds Modules of High-Risk Associated Biomarkers

JB Lund, S Li, J Baumbach, K Christensen, W Li, A Mohammadnejad, ...

The Journals of Gerontology: Series A 75 (12), 2249-2257, 2020

Mandates: UK Biotechnology and Biological Sciences Research Council, UK Economic and …

DNA methylation-based measures of accelerated biological ageing and the risk of dementia in the oldest-old: a study of the Lothian Birth Cohort 1921

RA Sibbett, DM Altschul, RE Marioni, IJ Deary, JM Starr, TC Russ

BMC psychiatry 20, 1-15, 2020

Mandates: UK Biotechnology and Biological Sciences Research Council, Chief Scientist …

[PDF] springer.com

Epigenetic measures of ageing predict the prevalence and incidence of leading causes of death and disease burden

RF Hillary, AJ Stevenson, DL McCartney, A Campbell, RM Walker, ...

Clinical epigenetics 12, 1-12, 2020

Mandates: US National Institutes of Health, Alzheimers's UK, UK Biotechnology and …

DNA methylation outlier burden, health, and ageing in Generation Scotland and the Lothian Birth Cohorts of 1921 and 1936

A Seeboth, DL McCartney, Y Wang, RF Hillary, AJ Stevenson, RM Walker, ...

Clinical epigenetics 12, 1-13, 2020

Mandates: Swedish Council for Health, Labor and Welfare, Swedish Research Council …

[PDF] springer.com

Characterisation of an inflammation-related epigenetic score and its association with cognitive ability

AJ Stevenson, DL McCartney, RF Hillary, A Campbell, SW Morris, ...

Clinical Epigenetics 12, 1-11, 2020

Mandates: Alzheimers's UK, UK Biotechnology and Biological Sciences Research Council …

An epigenome-wide association study of sex-specific chronological ageing

DL McCartney, F Zhang, RF Hillary, Q Zhang, AJ Stevenson, RM Walker, ...

Genome medicine 12, 1-11, 2020

Mandates: Australian Research Council, National Health and Medical Research Council …

A time-resolved proteomic and diagnostic map characterizes COVID-19 disease progression and predicts outcome

V Demichev, P Tober-Lau, T Nazarenko, C Thibeault, H Whitwell, ...

MedRxiv, 2020.11. 09.20228015, 2020

Mandates: Austrian Science Fund, German Research Foundation, Alzheimers's UK, UK …

[PDF] medrxiv.org

Increase in anticholinergic burden in the UK from 1990 to 2015: a UK Biobank study

J Mur, SR Cox, RE Marioni, G Muniz-Terrera, TC Russ

medRxiv, 2020.10. 16.20213884, 2020

Mandates: US National Institutes of Health, Alzheimers's UK, UK Medical Research …

An epigenetic proxy of chronic inflammation outperforms serum levels as a biomarker of brain ageing

ELS Conole, AJ Stevenson, C Green, SE Harris, SM Maniega, ...

medRxiv, 2020.10. 08.20205245, 2020

Mandates: US National Institutes of Health, UK Biotechnology and Biological Sciences …

[PDF] nature.com

Polygenic predictors of age-related decline in cognitive ability

SJ Ritchie, WD Hill, RE Marioni, G Davies, SP Hagenaars, SE Harris, ...

Molecular Psychiatry 25 (10), 2584-2598, 2020

Mandates: Alzheimers's UK, UK Biotechnology and Biological Sciences Research Council …

[PDF] nature.com

Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture

Q Zhang, J Sidorenko, B Couvy-Duchesne, RE Marioni, MJ Wright, ...

Nature communications 11 (1), 4799, 2020

Mandates: US National Institutes of Health, Australian Research Council, National …

DNA methylation signatures of C-reactive protein associations with structural neuroimaging measures and major depressive disorder

C Green, X Shen, AJ Stevenson, ELS Conole, MA Harris, MC Barbu, ...

medRxiv, 2020.08. 12.20173567, 2020

Mandates: US National Institutes of Health, Chief Scientist Office, Scottish Executive …

Creating and validating a DNA methylation-based proxy for Interleukin-6

AJ Stevenson, DA Gadd, RF Hillary, DL McCartney, A Campbell, ...

medRxiv, 2020.07. 20.20156935, 2020

Mandates: US National Institutes of Health, Australian Research Council, National …

[HTML] cell.com

Ultra-high-throughput clinical proteomics reveals classifiers of COVID-19 infection

CB Messner, V Demichev, D Wendisch, L Michalick, M White, A Freiwald, ...

Cell systems 11 (1), 11-24. e4, 2020

Mandates: German Research Foundation, Alzheimers's UK, Versus Arthritis, UK, UK …

[HTML] nih.gov

Blood DNA methylation sites predict death risk in a longitudinal study of 12,300 individuals

E Colicino, R Marioni, C Ward-Caviness, R Gondalia, W Guan, B Chen, ...

Aging (Albany NY) 12 (14), 14092, 2020

Mandates: US National Institutes of Health, US Department of Veterans Affairs, US …

[PDF] biorxiv.org

Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

DL McCartney, JL Min, RC Richmond, AT Lu, MK Sobczyk, G Davies, ...

BioRxiv, 2020.06. 29.133702, 2020

Mandates: US National Institutes of Health, Alzheimers's UK, Cancer Research UK, UK …

[PDF] nature.com