| Pharmacological targeting of a PWWP domain demonstrates cooperative control of NSD2 localization D Dilworth, RP Hanley, RF de Freitas, A Allali-Hassani, M Zhou, N Mehta, ... bioRxiv, 2021.03. 05.433782, 2021 | 7 | 2021 |
| A chemical probe to modulate human GID4 Pro/N-degron interactions DDG Owens, MER Maitland, A Khalili Yazdi, X Song, V Reber, ... Nature Chemical Biology, 1-12, 2024 | 6 | 2024 |
| Combinatorial anticancer drug screen identifies off-target effects of epigenetic chemical probes SH Barghout, MK Mann, A Aman, Y Yu, MG Alteen, AD Schimmer, ... ACS Chemical Biology 17 (10), 2801-2816, 2022 | 5 | 2022 |
| ChemBioPort: an online portal to navigate the structure, function and chemical inhibition of the human proteome L Liu, E Rovers, M Schapira Database 2022, baac088, 2022 | 5 | 2022 |
| Constrained Hiv V3 Loop Peptides as Novel Immunogens and Receptor Antagonists J Anglister, M Sharon, M Schapira, S Zolla-Pazner, O Rosen US Patent App. 10/544,399, 2008 | 5 | 2008 |
| Discovery and characterization of a chemical probe targeting the zinc-finger ubiquitin-binding domain of HDAC6 RJ Harding, I Franzoni, MK Mann, MM Szewczyk, B Mirabi, ... Journal of Medicinal Chemistry 66 (15), 10273-10288, 2023 | 4 | 2023 |
| Methods for computer-assisted PROTAC design E Rovers, M Schapira Methods in Enzymology 690, 311-340, 2023 | 4 | 2023 |
| Target 2035–an update on private sector contributions S Ackloo, AA Antolin, JM Bartolome, H Beck, A Bullock, UAK Betz, ... RSC Medicinal Chemistry 14 (6), 1002-1011, 2023 | 4 | 2023 |
| Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes–7 M Gütschow, JJ Vanden Eynde, J Jampilek, CB Kang, AA Mangoni, ... Molecules 25 (13), 2968, 2020 | 4 | 2020 |
| HAP40 orchestrates huntingtin structure for differential interaction with polyglutamine expanded exon 1 RJ Harding, JC Deme, JF Hevler, S Tamara, A Lemak, JP Cantle, ... bioRxiv, 2021.04. 02.438217, 2021 | 3 | 2021 |
| Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase. Nat Commun 12 (1): 4848 JA Newman, A Douangamath, S Yadzani, Y Yosaatmadja, A Aimon, ... | 3 | 2021 |
| Ten Simple Rules for Open Health Research A Bafeta, J Bobe, J Clucas, PP Gonsalves, C Gruson-Daniel, K Hudson, ... Preprints, 2019 | 3 | 2019 |
| Emerging structure-based computational methods to screen the exploding accessible chemical space C Bedart, CV Simoben, M Schapira Current Opinion in Structural Biology 86, 102812, 2024 | 2 | 2024 |
| Small Molecule Screen Identifies Non-catalytic USP3 Chemical Handle MK Mann, E Wolf, M Silva, HA Kwak, B Wilson, A Bolotokova, DJ Wilson, ... ACS omega 9 (1), 917-924, 2023 | 2 | 2023 |
| Drug Discovery in Low Data Regimes: Leveraging a Computational Pipeline for the Discovery of Novel SARS-CoV-2 Nsp14-MTase Inhibitors AK Nigam, MFD Hurley, F Li, E Konkoľová, M Klíma, J Trylčová, R Pollice, ... bioRxiv, 2023 | 2 | 2023 |
| A first-in-class, highly selective and cell-active allosteric inhibitor of protein arginine methyltransferase 6 (PRMT6) Y Shen, F Li, MM Szewczyk, L Halebelian, I Chau, MS Eram, CD Seña, ... bioRxiv, 2020.12. 04.412569, 2020 | 2 | 2020 |
| Ten simple rules for open human health research A Bafeta, J Bobe, J Clucas, PP Gonsalves, C Gruson-Daniel, KL Hudson, ... PLoS computational biology 16 (9), e1007846, 2020 | 2 | 2020 |
| Structural Genomics, Its Application in Chemistry, Biology, and Drug Discovery M Schapira Burger's Medicinal Chemistry and Drug Discovery, 571-601, 2010 | 2* | 2010 |
| Novel anti-HIV and anti-tumor proteins MAP30 and GAP31: molecular, biochemical, and structural insights into biological activities and mechanism. S Lee-Huang, PL Huang, XP Kong, M Schapira, PL Huang | 2 | 2003 |
| Subpocket Similarity-Based Hit Identification for Challenging Targets: Application to the WDR Domain of LRRK2 M Eguida, G Bret, F Sindt, F Li, I Chau, S Ackloo, C Arrowsmith, ... Journal of Chemical Information and Modeling 64 (13), 5344-5355, 2024 | 1 | 2024 |
