Articles with public access mandates - Mitsuhiko IkuraLearn more
Available somewhere: 100
Light-dependent regulation of structural flexibility in a photochromic fluorescent protein
H Mizuno, TK Mal, M Wälchli, A Kikuchi, T Fukano, R Ando, ...
Proceedings of the National Academy of Sciences 105 (27), 9227-9232, 2008
Mandates: Canadian Institutes of Health Research
Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry
L Zheng, PB Stathopulos, R Schindl, GY Li, C Romanin, M Ikura
Proceedings of the National Academy of Sciences 108 (4), 1337-1342, 2011
Mandates: Austrian Science Fund, Canadian Institutes of Health Research
A coiled-coil clamp controls both conformation and clustering of stromal interaction molecule 1 (STIM1)
M Fahrner, M Muik, R Schindl, C Butorac, P Stathopulos, L Zheng, I Jardin, ...
Journal of Biological Chemistry 289 (48), 33231-33244, 2014
Mandates: Austrian Science Fund, Canadian Institutes of Health Research, Heart and …
An autoinhibited structure of α-catenin and its implications for vinculin recruitment to adherens junctions
N Ishiyama, N Tanaka, K Abe, YJ Yang, YM Abbas, M Umitsu, B Nagar, ...
Journal of Biological Chemistry 288 (22), 15913-15925, 2013
Mandates: Canadian Institutes of Health Research
Molecular structure and target recognition of neuronal calcium sensor proteins
J Ames, S Lim, M Ikura
Frontiers in molecular neuroscience 5, 21802, 2012
Mandates: US National Institutes of Health, Canadian Institutes of Health Research
Biochemical and structural characterization of an intramolecular interaction in FOXO3a and its binding with p53
F Wang, CB Marshall, K Yamamoto, GY Li, MJ Plevin, H You, TW Mak, ...
Journal of molecular biology 384 (3), 590-603, 2008
Mandates: Canadian Institutes of Health Research
Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment
F Wang, CB Marshall, K Yamamoto, GY Li, GMC Gasmi-Seabrook, ...
Proceedings of the National Academy of Sciences 109 (16), 6078-6083, 2012
Mandates: Canadian Institutes of Health Research
Structure and identification of ADP-ribose recognition motifs of APLF and role in the DNA damage response
GY Li, RD McCulloch, AL Fenton, M Cheung, L Meng, M Ikura, CA Koch
Proceedings of the National Academy of Sciences 107 (20), 9129-9134, 2010
Mandates: Canadian Institutes of Health Research
Structural mechanism of transcriptional autorepression of the Escherichia coli RelB/RelE antitoxin/toxin module
GY Li, Y Zhang, M Inouye, M Ikura
Journal of molecular biology 380 (1), 107-119, 2008
Mandates: Canadian Institutes of Health Research
Crystal structure of type I ryanodine receptor amino-terminal β-trefoil domain reveals a disease-associated mutation “hot spot” loop
FJ Amador, S Liu, N Ishiyama, MJ Plevin, A Wilson, DH MacLennan, ...
Proceedings of the National Academy of Sciences 106 (27), 11040-11044, 2009
Mandates: Canadian Institutes of Health Research
Multiple calmodulin-binding sites positively and negatively regulate Arabidopsis CYCLIC NUCLEOTIDE-GATED CHANNEL12
TA DeFalco, CB Marshall, K Munro, HG Kang, W Moeder, M Ikura, ...
The Plant Cell 28 (7), 1738-1751, 2016
Mandates: US National Science Foundation, Canadian Institutes of Health Research …
Inhibitory mechanism of Escherichia coli RelE-RelB toxin-antitoxin module involves a helix displacement near an mRNA interferase active site
GY Li, Y Zhang, M Inouye, M Ikura
Journal of Biological Chemistry 284 (21), 14628-14636, 2009
Mandates: US National Institutes of Health, Canadian Institutes of Health Research
Force-dependent allostery of the α-catenin actin-binding domain controls adherens junction dynamics and functions
N Ishiyama, R Sarpal, MN Wood, SK Barrick, T Nishikawa, H Hayashi, ...
Nature communications 9 (1), 5121, 2018
Mandates: US National Science Foundation, US National Institutes of Health, Canadian …
Cholesterol modulates Orai1 channel function
I Derler, I Jardin, PB Stathopulos, M Muik, M Fahrner, V Zayats, ...
Science signaling 9 (412), ra10-ra10, 2016
Mandates: Austrian Science Fund, Canadian Institutes of Health Research, Heart and …
The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1
J Cullis, D Meiri, MJ Sandi, N Radulovich, OA Kent, M Medrano, ...
Cancer cell 25 (2), 181-195, 2014
Mandates: Canadian Institutes of Health Research, Ontario Institute for Cancer Research
Mechanistic insight into the microtubule and actin cytoskeleton coupling through dynein-dependent RhoGEF inhibition
D Meiri, CB Marshall, MA Greeve, B Kim, M Balan, F Suarez, C Bakal, ...
Molecular cell 45 (5), 642-655, 2012
Mandates: Canadian Institutes of Health Research
Ryanodine receptor calcium release channels: lessons from structure–function studies
FJ Amador, PB Stathopulos, M Enomoto, M Ikura
The FEBS journal 280 (21), 5456-5470, 2013
Mandates: Canadian Institutes of Health Research
Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation
Y Kano, T Gebregiworgis, CB Marshall, N Radulovich, BPK Poon, ...
Nature communications 10 (1), 224, 2019
Mandates: US National Institutes of Health, Canadian Cancer Society, Canadian …
Structural insights into endoplasmic reticulum stored calcium regulation by inositol 1, 4, 5-trisphosphate and ryanodine receptors
MD Seo, M Enomoto, N Ishiyama, PB Stathopulos, M Ikura
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (9), 1980-1991, 2015
Mandates: Canadian Institutes of Health Research, Heart and Stroke Foundation of …
The N-terminus of hTERT contains a DNA-binding domain and is required for telomerase activity and cellular immortalization
DCF Sealey, L Zheng, MAS Taboski, J Cruickshank, M Ikura, ...
Nucleic acids research 38 (6), 2019-2035, 2010
Mandates: US National Institutes of Health, Canadian Institutes of Health Research
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