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Proteomic identification of phosphorylation-dependent septin 7 interactors that drive dendritic spine formation
S Byeon, B Werner, R Falter, K Davidsen, C Snyder, SE Ong, S Yadav
Frontiers in Cell and Developmental Biology 10, 836746, 2022
Mandates: US National Institutes of Health
Parallel chemoselective profiling for mapping protein structure
ZE Potter, HT Lau, S Chakraborty, L Fang, M Guttman, SE Ong, ...
Cell chemical biology 27 (8), 1084-1096. e4, 2020
Mandates: US National Institutes of Health
N-glycosylation of α1D-adrenergic receptor N-terminal domain is required for correct trafficking, function, and biogenesis
EM Janezic, SML Lauer, RG Williams, M Chungyoun, KS Lee, ...
Scientific reports 10 (1), 7209, 2020
Mandates: US National Institutes of Health
CCDC186 recruits EARP and controls dense-core vesicle cargo sorting by exit
J Cattin-Ortolá, I Topalidou, HT Lau, B Hummer, CS Asensio, SE Ong, ...
BioRxiv, 616458, 2019
Mandates: US National Institutes of Health
Noncanonical translation via deadenylated 3′ UTRs maintains primordial germ cells
YN Jin, PJ Schlueter, N Jurisch-Yaksi, PY Lam, S Jin, WY Hwang, ...
Nature chemical biology 14 (9), 844-852, 2018
Mandates: US National Institutes of Health, US Department of Agriculture
Quantifying in vivo, site-specific changes in protein methylation with SILAC
HT Lau, KA Lewis, SE Ong
Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) Methods and …, 2014
Mandates: US National Institutes of Health
Neurodevelopmental disorder–associated mutations in TAOK1 reveal its function as a plasma membrane remodeling kinase
N Beeman, T Sapre, SE Ong, S Yadav
Science signaling 16 (766), eadd3269, 2023
Mandates: US National Institutes of Health
KiRNet: Kinase-centered network propagation of pharmacological screen results
T Bello, M Chan, M Golkowski, AG Xue, N Khasnavis, M Ceribelli, SE Ong, ...
Cell reports methods 1 (2), 2021
Mandates: US National Science Foundation, US National Institutes of Health
Phosphoproteomic analysis as an approach for understanding molecular mechanisms of cAMP-dependent actions
JA Beavo, M Golkowski, M Shimizu-Albergine, MC Beltejar, KE Bornfeldt, ...
Molecular Pharmacology 99 (5), 342-357, 2021
Mandates: US National Institutes of Health
Proximity biotinylation to define the local environment of the protein kinase A catalytic subunit in adrenal cells
MH Omar, SM Lauer, HT Lau, M Golkowski, SE Ong, JD Scott
STAR protocols 4 (1), 101992, 2023
Mandates: US National Institutes of Health
Computationally designed sensors for endogenous Ras activity reveal signaling effectors within oncogenic granules
JZ Zhang, WH Nguyen, N Greenwood, JC Rose, SE Ong, DJ Maly, ...
bioRxiv, 2022.11. 22.517009, 2022
Mandates: US National Institutes of Health, Howard Hughes Medical Institute
Ion-pairing with triethylammonium acetate improves solid-phase extraction of ADP-ribosylated peptides
RL McPherson, SE Ong, AKL Leung
Journal of proteome research 19 (2), 984-990, 2019
Mandates: US National Institutes of Health
PARprolink: a photoaffinity probe for identifying poly (ADP-ribose)-binding proteins
M Dasovich, MQ Beckett, S Bailey, SE Ong, MM Greenberg, AKL Leung
bioRxiv, 2020.12. 28.424596, 2020
Mandates: US National Institutes of Health
Single-cell signaling analysis reveals that Major Vault Protein facilitates RasG12C inhibitor resistance
JZ Zhang, SE Ong, D Baker, DJ Maly
bioRxiv, 2023
Mandates: Howard Hughes Medical Institute
Discovery of a Cushing’s syndrome protein kinase A mutant that biases signaling through type I AKAPs
MH Omar, DP Byrne, S Shrestha, TM Lakey, KS Lee, SM Lauer, ...
Science Advances 10 (8), eadl1258, 2024
Mandates: UK Biotechnology and Biological Sciences Research Council, Cancer Research UK
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution
JZ Zhang, WH Nguyen, N Greenwood, JC Rose, SE Ong, DJ Maly, ...
Nature Biotechnology, 1-11, 2024
Mandates: Howard Hughes Medical Institute
Designed sensors reveal normal and oncogenic Ras signaling in endomembranes and condensates
JZ Zhang, WH Nguyen, JC Rose, SE Ong, DJ Maly, D Baker
Molecular Cancer Research 21 (5), 2023
Mandates: US National Institutes of Health, Howard Hughes Medical Institute
Displacement of PKA catalytic subunit from AKAP signaling islands drives pathology in Cushing’s syndrome
MH Omar, DP Byrne, KN Jones, TM Lakey, KB Collins, KS Lee, LA Daly, ...
bioRxiv, 2021.10. 18.464848, 2021
Mandates: US National Institutes of Health, UK Biotechnology and Biological Sciences …
Multiplexed profiling of kinase interactomes quantifies cellular network plasticity
M Golkowski, A Lius, T Sapre, HT Lau, T Moreno, DJ Maly, SE Ong
bioRxiv, 2021.09. 14.460283, 2021
Mandates: US National Institutes of Health
Kinome-centric pharmacoproteomics identifies signaling pathways underlying cellular responses to targeted cancer drugs
M Golkowski, HT Lau, M Chan, H Kenerson, VN Vidadala, A Shoemaker, ...
bioRxiv, 849281, 2019
Mandates: US Department of Defense, US National Institutes of Health, German Research …
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