Articles with public access mandates - Mitsuhiko IkuraLearn more
Available somewhere: 100
A Ca2+-dependent mechanism of neuronal survival mediated by the microtubule-associated protein p600
C Belzil, G Neumayer, AP Vassilev, KL Yap, H Konishi, S Rivest, ...
Journal of Biological Chemistry 288 (34), 24452-24464, 2013
Mandates: US National Institutes of Health, Canadian Cancer Society, Canadian …
α-Catenin homodimers are recruited to phosphoinositide-activated membranes to promote adhesion
MN Wood, N Ishiyama, I Singaram, CM Chung, AS Flozak, A Yemelyanov, ...
Journal of Cell Biology 216 (11), 3767-3783, 2017
Mandates: US National Science Foundation, US National Institutes of Health, Canadian …
Lung cancer driven by BRAFG469V mutation is targetable by EGFR kinase inhibitors
KG Huo, H Notsuda, Z Fang, NF Liu, T Gebregiworgis, Q Li, NA Pham, ...
Journal of Thoracic Oncology 17 (2), 277-288, 2022
Mandates: Canadian Cancer Society, Canadian Institutes of Health Research
Oncogenic KRAS G12D mutation promotes dimerization through a second, phosphatidylserine–dependent interface: a model for KRAS oligomerization
KY Lee, M Enomoto, T Gebregiworgis, GMC Gasmi-Seabrook, M Ikura, ...
Chemical Science 12 (38), 12827-12837, 2021
Mandates: Canadian Cancer Society, Canadian Institutes of Health Research, Natural …
Biochemical classification of disease-associated mutants of RAS-like protein expressed in many tissues (RIT1)
Z Fang, CB Marshall, JC Yin, MT Mazhab-Jafari, GMC Gasmi-Seabrook, ...
Journal of Biological Chemistry 291 (30), 15641-15652, 2016
Mandates: Canadian Cancer Society
Forkhead followed by disordered tail: The intrinsically disordered regions of FOXO3a
F Wang, CB Marshall, M Ikura
Intrinsically Disordered Proteins 3 (1), e1056906, 2015
Mandates: Canadian Institutes of Health Research
A non-canonical calmodulin target motif comprising a polybasic region and lipidated terminal residue regulates localization
BMM Grant, M Enomoto, M Ikura, CB Marshall
International Journal of Molecular Sciences 21 (8), 2751, 2020
Mandates: Canadian Cancer Society, Canadian Institutes of Health Research, Heart and …
p120RasGAP is a mediator of rho pathway activation and tumorigenicity in the DLD1 colorectal cancer cell line
SL Organ, J Hai, N Radulovich, CB Marshall, L Leung, T Sasazuki, ...
PloS one 9 (1), e86103, 2014
Mandates: Canadian Institutes of Health Research
Molecular basis of photochromism of a fluorescent protein revealed by direct 13C detection under laser illumination
H Mizuno, TK Mal, M Wälchli, T Fukano, M Ikura, A Miyawaki
Journal of biomolecular NMR 48, 237-246, 2010
Mandates: Canadian Institutes of Health Research
Conformational states of syntaxin-1 govern the necessity of N-peptide binding in exocytosis of PC12 cells and Caenorhabditis elegans
S Park, NR Bin, M Michael Rajah, B Kim, TC Chou, SA Kang, K Sugita, ...
Molecular Biology of the Cell 27 (4), 669-685, 2016
Mandates: Canadian Institutes of Health Research, Heart and Stroke Foundation of …
Coordination of a single calcium ion in the EF-hand maintains the off state of the stromal interaction molecule luminal domain
M Enomoto, T Nishikawa, SI Back, N Ishiyama, L Zheng, PB Stathopulos, ...
Journal of molecular biology 432 (2), 367-383, 2020
Mandates: Canadian Institutes of Health Research, Natural Sciences and Engineering …
From stores to sinks: structural mechanisms of cytosolic calcium regulation
M Enomoto, T Nishikawa, N Siddiqui, S Chung, M Ikura, PB Stathopulos
Membrane Dynamics and Calcium Signaling, 215-251, 2017
Mandates: Canadian Institutes of Health Research, Natural Sciences and Engineering …
Regulation of GTPase function by autophosphorylation
CW Johnson, HS Seo, EM Terrell, MH Yang, F KleinJan, T Gebregiworgis, ...
Molecular cell 82 (5), 950-968. e14, 2022
Mandates: US National Science Foundation, US Department of Energy, US National …
Multiplexed real-time NMR GTPase assay for simultaneous monitoring of multiple guanine nucleotide exchange factor activities from human cancer cells and organoids
T Gebregiworgis, CB Marshall, T Nishikawa, N Radulovich, MJ Sandi, ...
Journal of the American Chemical Society 140 (13), 4473-4476, 2018
Mandates: Canadian Cancer Society, Canadian Institutes of Health Research, Natural …
Force-induced changes of α-catenin conformation stabilize vascular junctions independently of vinculin
CN Duong, R Brückner, M Schmitt, AF Nottebaum, LJ Braun, ...
Journal of Cell Science 134 (24), jcs259012, 2021
Mandates: German Research Foundation
Tankyrase regulates epithelial lumen formation via suppression of Rab11 GEFs
AA Chandrakumar, É Coyaud, CB Marshall, M Ikura, B Raught, ...
Journal of Cell Biology 220 (7), e202008037, 2021
Mandates: Canadian Institutes of Health Research, Natural Sciences and Engineering …
Distinct roles of ATM and ATR in the regulation of ARP8 phosphorylation to prevent chromosome translocations
J Sun, L Shi, A Kinomura, A Fukuto, Y Horikoshi, Y Oma, M Harata, ...
Elife 7, e32222, 2018
Mandates: Netherlands Organisation for Scientific Research, Dutch Cancer Society
Secretion of human superoxide dismutase in Escherichia coli using the condensed single‐protein‐production system
L Mao, PB Stathopulos, M Ikura, M Inouye
Protein Science 19 (12), 2330-2335, 2010
Mandates: US National Institutes of Health
Structures of RGL1 RAS-association domain in complex with KRAS and the oncogenic G12V mutant
BJ Eves, T Gebregiworgis, GMC Gasmi-Seabrook, DA Kuntz, GG Privé, ...
Journal of Molecular Biology 434 (9), 167527, 2022
Mandates: Canadian Cancer Society, Canadian Institutes of Health Research, Natural …
The p.E152K-STIM1 mutation deregulates Ca2+ signaling contributing to chronic pancreatitis
M Burgos, R Philippe, F Antigny, P Buscaglia, E Masson, S Mukherjee, ...
Journal of Cell Science 134 (3), jcs244012, 2021
Mandates: Swiss National Science Foundation, Canadian Institutes of Health Research …
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