Targeted glycan degradation potentiates the anticancer immune response in vivo MA Gray, MA Stanczak, NR Mantuano, H Xiao, JFA Pijnenborg, ... Nature Chemical Biology 16 (12), 1376-1384, 2020 | 256 | 2020 |
DNA origami protection and molecular interfacing through engineered sequence-defined peptoids ST Wang, MA Gray, S Xuan, Y Lin, J Byrnes, AI Nguyen, N Todorova, ... Proceedings of the National Academy of Sciences 117 (12), 6339-6348, 2020 | 115 | 2020 |
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7 S Wisnovsky, L Möckl, SA Malaker, K Pedram, GT Hess, NM Riley, ... Proceedings of the National Academy of Sciences 118 (5), e2015024118, 2021 | 95 | 2021 |
Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade MA Stanczak, N Rodrigues Mantuano, N Kirchhammer, DE Sanin, ... Science Translational Medicine 14 (669), eabj1270, 2022 | 92 | 2022 |
Bump-and-hole engineering identifies specific substrates of glycosyltransferases in living cells B Schumann, SA Malaker, SP Wisnovsky, MF Debets, AJ Agbay, ... Molecular cell 78 (5), 824-834. e15, 2020 | 84 | 2020 |
CRISPR-Cas9 screens identify regulators of antibody–drug conjugate toxicity CK Tsui, RM Barfield, CR Fischer, DW Morgens, A Li, BAH Smith, ... Nature chemical biology 15 (10), 949-958, 2019 | 68 | 2019 |
Engineering orthogonal polypeptide GalNAc-transferase and UDP-sugar pairs J Choi, LJS Wagner, SBPE Timmermans, SA Malaker, B Schumann, ... Journal of the American Chemical Society 141 (34), 13442-13453, 2019 | 62 | 2019 |
A nanobody activation immunotherapeutic that selectively destroys HER2‐positive breast cancer cells MA Gray, RN Tao, SM DePorter, DA Spiegel, BR McNaughton Chembiochem 17 (2), 155-158, 2016 | 60 | 2016 |
Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth E Scott, K Hodgson, B Calle, H Turner, K Cheung, A Bermudez, ... Oncogene 42 (12), 926-937, 2023 | 25 | 2023 |
Inverting family GH156 sialidases define an unusual catalytic motif for glycosidase action P Bule, L Chuzel, E Blagova, L Wu, MA Gray, B Henrissat, E Rapp, ... Nature Communications 10 (1), 4816, 2019 | 19 | 2019 |
Isotype-specific agglutination-PCR (ISAP): A sensitive and multiplex method for measuring allergen-specific IgE C Tsai, K Mukai, PV Robinson, MA Gray, MB Waschmann, SC Lyu, M Tsai, ... Journal of Allergy and Clinical Immunology 141 (5), 1901-1904. e15, 2018 | 15 | 2018 |
Chemical generation of checkpoint inhibitory T cell engagers for the treatment of cancer PA Szijj, MA Gray, MK Ribi, C Bahou, JCF Nogueira, CR Bertozzi, ... Nature Chemistry, 1-12, 2023 | 13 | 2023 |
Targeted desialylation overcomes glyco-immune checkpoints and potentiates the anticancer immune response in vivo MA Gray, MA Stanczak, H Xiao, JFA Pijnenborg, NR Mantuano, ... ChemRxiv 8187146, v2, 2019 | 10 | 2019 |
Antibody-lectin chimeras for glyco-immune checkpoint blockade JC Stark, MA Gray, S Wisnovsky, I Ibarlucea-Benitez, NM Riley, MK Ribi, ... BioRxiv, 2022.10. 26.513931, 2022 | 9 | 2022 |
Mutagenesis modulates the uptake efficiency, cell-selectivity, and functional enzyme delivery of a protein transduction domain SM DePorter, I Lui, VJ Bruce, MA Gray, M Lopez-Islas, BR McNaughton Molecular bioSystems 10 (1), 18-23, 2014 | 9 | 2014 |
Chemical precision glyco-mutagenesis by glycosyltransferase engineering in living cells B Schumann, SA Malaker, SP Wisnovsky, MF Debets, AJ Agbay, ... BioRxiv, 669861, 2019 | 4 | 2019 |
Mutational screens highlight glycosylation as a modulator of colony-stimulating factor 3 receptor (CSF3R) activity MJ Hollander, SA Malaker, NM Riley, I Perez, NM Abney, MA Gray, ... Journal of Biological Chemistry 299 (6), 2023 | 1 | 2023 |
Conjugates for targeted cell surface editing EC Woods, H Xiao, CR Bertozzi, M Gray US Patent 11,459,398, 2022 | 1 | 2022 |
A one-pot synthesis of micron-sized and nanoscale poly (N-acryloxysuccinimide-co-N-vinylpyrrolidone) particles SM DePorter, NK Hendricks, MA Gray, BR McNaughton Tetrahedron Letters 53 (47), 6436-6438, 2012 | 1 | 2012 |
Genome-Wide CRISPR screens reveal specific ligands for glycan-binding immune checkpoint receptors S Wisnovsky, L Mockl, SA Malaker, K Pedram, GT Hess, NM Riley, ... GLYCOBIOLOGY 31 (12), 1682-1683, 2021 | | 2021 |