Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice FMS de Vrij, J Levenga, HC Van der Linde, SK Koekkoek, CI De Zeeuw, ... Neurobiology of disease 31 (1), 127-132, 2008 | 354 | 2008 |
CGG repeat in the FMR1 gene: size matters R Willemsen, J Levenga, BA Oostra Clinical genetics 80 (3), 214-225, 2011 | 235 | 2011 |
Nicotine reverses hypofrontality in animal models of addiction and schizophrenia F Koukouli, M Rooy, D Tziotis, KA Sailor, HC O'Neill, J Levenga, M Witte, ... Nature medicine 23 (3), 347-354, 2017 | 210 | 2017 |
Olig2 overexpression induces the in vitro differentiation of neural stem cells into mature oligodendrocytes S Copray, V Balasubramaniyan, J Levenga, J De Bruijn, R Liem, ... Stem cells 24 (4), 1001-1010, 2006 | 156 | 2006 |
AFQ056, a new mGluR5 antagonist for treatment of fragile X syndrome J Levenga, S Hayashi, FMS de Vrij, SK Koekkoek, HC van der Linde, ... Neurobiology of disease 42 (3), 311-317, 2011 | 139 | 2011 |
Tau pathology induces loss of GABAergic interneurons leading to altered synaptic plasticity and behavioral impairments J Levenga, P Krishnamurthy, H Rajamohamedsait, H Wong, TF Franke, ... Acta neuropathologica communications 1, 1-14, 2013 | 132 | 2013 |
Potential therapeutic interventions for fragile X syndrome J Levenga, FMS de Vrij, BA Oostra, R Willemsen Trends in molecular medicine 16 (11), 516-527, 2010 | 111 | 2010 |
AKT isoforms have distinct hippocampal expression and roles in synaptic plasticity J Levenga, H Wong, RA Milstead, BN Keller, LE LaPlante, CA Hoeffer Elife 6, e30640, 2017 | 105 | 2017 |
Rescue of dendritic spine phenotype in Fmr1 KO mice with the mGluR5 antagonist AFQ056/Mavoglurant AS Pop, J Levenga, CEF de Esch, RAM Buijsen, IM Nieuwenhuizen, T Li, ... Psychopharmacology 231, 1227-1235, 2014 | 93 | 2014 |
Subregion-specific dendritic spine abnormalities in the hippocampus of Fmr1 KO mice J Levenga, FMS de Vrij, RAM Buijsen, T Li, IM Nieuwenhuizen, A Pop, ... Neurobiology of learning and memory 95 (4), 467-472, 2011 | 65 | 2011 |
RCAN1 overexpression promotes age-dependent mitochondrial dysregulation related to neurodegeneration in Alzheimer’s disease H Wong, J Levenga, P Cain, B Rothermel, E Klann, C Hoeffer Acta neuropathologica 130, 829-843, 2015 | 63 | 2015 |
Affinity of Tau antibodies for solubilized pathological Tau species but not their immunogen or insoluble Tau aggregates predicts in vivo and ex vivo efficacy EE Congdon, Y Lin, HB Rajamohamedsait, DB Shamir, S Krishnaswamy, ... Molecular neurodegeneration 11, 1-24, 2016 | 60 | 2016 |
Perturbation of dendritic protrusions in intellectual disability J Levenga, R Willemsen Down Syndrome: From Understanding the Neurobiology to Therapy: From …, 2012 | 52 | 2012 |
Ultrastructural analysis of the functional domains in FMRP using primary hippocampal mouse neurons J Levenga, RAM Buijsen, M Rifé, H Moine, DL Nelson, BA Oostra, ... Neurobiology of disease 35 (2), 241-250, 2009 | 31 | 2009 |
Isoform-specific roles for AKT in affective behavior, spatial memory, and extinction related to psychiatric disorders H Wong, J Levenga, L LaPlante, B Keller, A Cooper-Sansone, C Borski, ... Elife 9, e56630, 2020 | 30 | 2020 |
Regulator of calcineurin 1 modulates expression of innate anxiety and anxiogenic responses to selective serotonin reuptake inhibitor treatment CA Hoeffer, H Wong, P Cain, J Levenga, KK Cowansage, Y Choi, C Davy, ... Journal of Neuroscience 33 (43), 16930-16944, 2013 | 23 | 2013 |
Sleep behavior and EEG oscillations in aged Dp (16) 1Yey/+ mice: a down syndrome model J Levenga, DJ Peterson, P Cain, CA Hoeffer Neuroscience 376, 117-126, 2018 | 15 | 2018 |
Immunohistological examination of AKT isoforms in the brain: cell-type specificity that may underlie AKT’s role in complex brain disorders and neurological disease J Levenga, H Wong, R Milstead, L LaPlante, CA Hoeffer Cerebral cortex communications 2 (2), tgab036, 2021 | 11 | 2021 |
A novel CRISPR interference effector enabling functional gene characterization with synthetic guide RNAs C Mills, A Riching, A Keller, J Stombaugh, A Haupt, E Maksimova, ... The CRISPR journal 5 (6), 769-786, 2022 | 4 | 2022 |
Synaptophysin is a β-Amyloid Target that Regulates Synaptic Plasticity and Seizure Susceptibility in an Alzhiemer’s Model DJ Adams, C Shen, J Levenga, T Basta, SP Eisenberg, J Mapes, ... BioRxiv, 129551, 2017 | 4 | 2017 |