Susceptibility of different mouse wild type strains to develop diet-induced NAFLD/AFLD-associated liver disease VHI Fengler, T Macheiner, SM Kessler, B Czepukojc, K Gemperlein, ... PloS one 11 (5), e0155163, 2016 | 86 | 2016 |
IMP2/p62 induces genomic instability and an aggressive hepatocellular carcinoma phenotype SM Kessler, S Laggai, A Barghash, CS Schultheiss, E Lederer, M Artl, ... Cell death & disease 6 (10), e1894-e1894, 2015 | 79 | 2015 |
IGF2 mRNA binding protein p62/IMP2-2 in hepatocellular carcinoma: antiapoptotic action is independent of IGF2/PI3K signaling SM Kessler, J Pokorny, V Zimmer, S Laggai, F Lammert, RM Bohle, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 304 (4 …, 2013 | 78 | 2013 |
Overexpression of the IGF2-mRNA binding protein p62 in transgenic mice induces a steatotic phenotype E Tybl, FD Shi, SM Kessler, S Tierling, J Walter, RM Bohle, S Wieland, ... Journal of hepatology 54 (5), 994-1001, 2011 | 76 | 2011 |
The insulin-like growth factor 2 (IGF2) mRNA-binding protein p62/IGF2BP2-2 as a promoter of NAFLD and HCC? Y Simon, SM Kessler, RM Bohle, J Haybaeck, AK Kiemer Gut 63 (5), 861-863, 2014 | 74 | 2014 |
The insulin-like growth factor 2 mRNA binding protein IMP2/IGF2BP2 is overexpressed and correlates with poor survival in pancreatic cancer C Dahlem, A Barghash, P Puchas, J Haybaeck, SM Kessler International journal of molecular sciences 20 (13), 3204, 2019 | 71 | 2019 |
Glucocorticoid-induced leucine zipper: a critical factor in macrophage endotoxin tolerance J Hoppstädter, SM Kessler, S Bruscoli, H Huwer, C Riccardi, AK Kiemer The Journal of Immunology 194 (12), 6057-6067, 2015 | 69 | 2015 |
Downregulation of the glucocorticoid-induced leucine zipper (GILZ) promotes vascular inflammation RT Hahn, J Hoppstädter, K Hirschfelder, N Hachenthal, B Diesel, ... Atherosclerosis 234 (2), 391-400, 2014 | 64 | 2014 |
The long non-coding RNA H19 suppresses carcinogenesis and chemoresistance in hepatocellular carcinoma CS Schultheiss, S Laggai, B Czepukojc, UK Hussein, M List, A Barghash, ... Cell Stress 1 (1), 37, 2017 | 63 | 2017 |
Elevated expression of the IGF2 mRNA binding protein 2 (IGF2BP2/IMP2) is linked to short survival and metastasis in esophageal adenocarcinoma A Barghash, N Golob-Schwarzl, V Helms, J Haybaeck, SM Kessler Oncotarget 7 (31), 49743, 2016 | 60 | 2016 |
Fatty acid elongation in non-alcoholic steatohepatitis and hepatocellular carcinoma SM Kessler, Y Simon, K Gemperlein, K Gianmoena, C Cadenas, ... International journal of molecular sciences 15 (4), 5762-5773, 2014 | 60 | 2014 |
The IGF2 mRNA binding protein p62/IGF2BP2-2 induces fatty acid elongation as a critical feature of steatosis [S] S Laggai, SM Kessler, S Boettcher, V Lebrun, K Gemperlein, E Lederer, ... Journal of lipid research 55 (6), 1087-1097, 2014 | 59 | 2014 |
Hsp72 protects against liver injury via attenuation of hepatocellular death, oxidative stress, and JNK signaling K Levada, N Guldiken, X Zhang, G Vella, FR Mo, LP James, J Haybaeck, ... Journal of hepatology 68 (5), 996-1005, 2018 | 50 | 2018 |
Overexpression of IGF2 mRNA‐Binding Protein 2 (IMP2/p62) as a Feature of Basal‐like Breast Cancer Correlates with Short Survival A Barghash, V Helms, SM Kessler Scandinavian journal of immunology 82 (2), 142-143, 2015 | 48 | 2015 |
Rapid chromatographic method to decipher distinct alterations in lipid classes in NAFLD/NASH S Laggai, Y Simon, T Ranssweiler, AK Kiemer, SM Kessler World journal of hepatology 5 (10), 558, 2013 | 43 | 2013 |
First small-molecule inhibitors targeting the RNA-binding protein IGF2BP2/IMP2 for cancer therapy C Dahlem, A Abuhaliema, SM Kessler, T Kröhler, BGE Zoller, S Chanda, ... ACS chemical biology 17 (2), 361-375, 2022 | 40 | 2022 |
IMP2/IGF2BP2 expression, but not IMP1 and IMP3, predicts poor outcome in patients and high tumor growth rate in xenograft models of gallbladder cancer SM Kessler, E Lederer, S Laggai, N Golob-Schwarzl, K Hosseini, ... Oncotarget 8 (52), 89736, 2017 | 37 | 2017 |
The Good, the Bad, the Question–H19 in Hepatocellular Carcinoma L Tietze, SM Kessler Cancers 12 (5), 1261, 2020 | 36 | 2020 |
Thioholgamide A, a new anti-proliferative anti-tumor agent, modulates macrophage polarization and metabolism C Dahlem, WX Siow, M Lopatniuk, WKF Tse, SM Kessler, SH Kirsch, ... Cancers 12 (5), 1288, 2020 | 35 | 2020 |
Hepatic interleukin-6 production is maintained during endotoxin tolerance and facilitates lipid accumulation A Dembek, S Laggai, SM Kessler, B Czepukojc, Y Simon, AK Kiemer, ... Immunobiology 222 (6), 786-796, 2017 | 35 | 2017 |