The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-β F Martinon, K Burns, J Tschopp Molecular cell 10 (2), 417-426, 2002 | 7000 | 2002 |
Gout-associated uric acid crystals activate the NALP3 inflammasome F Martinon, V Pétrilli, A Mayor, A Tardivel, J Tschopp Nature 440 (7081), 237-241, 2006 | 5939 | 2006 |
The inflammasomes: guardians of the body F Martinon, A Mayor, J Tschopp Annual review of immunology 27 (1), 229-265, 2009 | 3036 | 2009 |
NALP3 forms an IL-1β-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder L Agostini, F Martinon, K Burns, MF McDermott, PN Hawkins, J Tschopp Immunity 20 (3), 319-325, 2004 | 2079 | 2004 |
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration V Petrilli, S Papin, C Dostert, A Mayor, F Martinon, J Tschopp Cell Death & Differentiation 14 (9), 1583-1589, 2007 | 1728 | 2007 |
Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases F Martinon, J Tschopp Cell 117 (5), 561-574, 2004 | 1259 | 2004 |
RIP1 is an essential mediator of Toll-like receptor 3–induced NF-κB activation E Meylan, K Burns, K Hofmann, V Blancheteau, F Martinon, M Kelliher, ... Nature immunology 5 (5), 503-507, 2004 | 1130 | 2004 |
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages F Martinon, X Chen, AH Lee, LH Glimcher Nature immunology 11 (5), 411-418, 2010 | 1054 | 2010 |
Inflammatory caspases and inflammasomes: master switches of inflammation F Martinon, J Tschopp Cell Death & Differentiation 14 (1), 10-22, 2007 | 1046 | 2007 |
NALPs: a novel protein family involved in inflammation J Tschopp, F Martinon, K Burns Nature reviews Molecular cell biology 4 (2), 95-104, 2003 | 989 | 2003 |
NLRs join TLRs as innate sensors of pathogens F Martinon, J Tschopp Trends in immunology 26 (8), 447-454, 2005 | 851 | 2005 |
MyD88, an adapter protein involved in interleukin-1 signaling K Burns, F Martinon, C Esslinger, H Pahl, P Schneider, JL Bodmer, ... Journal of biological chemistry 273 (20), 12203-12209, 1998 | 797 | 1998 |
The caspase-8 inhibitor FLIP promotes activation of NF-κB and Erk signaling pathways T Kataoka, RC Budd, N Holler, M Thome, F Martinon, M Irmler, K Burns, ... Current biology 10 (11), 640-648, 2000 | 737 | 2000 |
Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor K Burns, J Clatworthy, L Martin, F Martinon, C Plumpton, B Maschera, ... Nature cell biology 2 (6), 346-351, 2000 | 717 | 2000 |
Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome F Martinon, L Agostini, E Meylan, J Tschopp Current Biology 14 (21), 1929-1934, 2004 | 703 | 2004 |
Signaling by ROS drives inflammasome activation F Martinon European journal of immunology 40 (3), 616-619, 2010 | 698 | 2010 |
The unfolded protein response: integrating stress signals through the stress sensor IRE1α C Hetz, F Martinon, D Rodriguez, LH Glimcher Physiological reviews 91 (4), 1219-1243, 2011 | 679 | 2011 |
Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response JA Kummer, R Broekhuizen, H Everett, L Agostini, L Kuijk, F Martinon, ... Journal of Histochemistry & Cytochemistry 55 (5), 443-452, 2007 | 646 | 2007 |
A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses A Mayor, F Martinon, T De Smedt, V Pétrilli, J Tschopp Nature immunology 8 (5), 497-503, 2007 | 547 | 2007 |
Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex N Holler, A Tardivel, M Kovacsovics-Bankowski, S Hertig, O Gaide, ... Molecular and cellular biology 23 (4), 1428-1440, 2003 | 539 | 2003 |