Adipose tissue as an endocrine organ S Galic, JS Oakhill, GR Steinberg Molecular and cellular endocrinology 316 (2), 129-139, 2010 | 2523 | 2010 |
Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin MD Fullerton, S Galic, K Marcinko, S Sikkema, T Pulinilkunnil, ZP Chen, ... Nature medicine 19 (12), 1649-1654, 2013 | 916 | 2013 |
Reactive oxygen species enhance insulin sensitivity K Loh, H Deng, A Fukushima, X Cai, B Boivin, S Galic, C Bruce, ... Cell metabolism 10 (4), 260-272, 2009 | 675 | 2009 |
Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity S Galic, MD Fullerton, JD Schertzer, S Sikkema, K Marcinko, CR Walkley, ... The Journal of clinical investigation 121 (12), 4903-4915, 2011 | 371 | 2011 |
Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B TC Meng, DA Buckley, S Galic, T Tiganis, NK Tonks Journal of Biological Chemistry 279 (36), 37716-37725, 2004 | 322 | 2004 |
Coordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTP S Galic, C Hauser, BB Kahn, FG Haj, BG Neel, NK Tonks, T Tiganis Molecular and cellular biology 25 (2), 819-829, 2005 | 250 | 2005 |
T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice F Wiede, BJ Shields, SH Chew, K Kyparissoudis, C Van Vliet, S Galic, ... The Journal of clinical investigation 121 (12), 4758-4774, 2011 | 236 | 2011 |
Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP S Galic, M Klingler-Hoffmann, MT Fodero-Tavoletti, MA Puryer, TC Meng, ... Molecular and cellular biology, 2003 | 223 | 2003 |
AMPK β1 deletion reduces appetite, preventing obesity and hepatic insulin resistance N Dzamko, BJW van Denderen, AL Hevener, SB Jørgensen, J Honeyman, ... Journal of Biological Chemistry 285 (1), 115-122, 2010 | 209 | 2010 |
Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance K Loh, A Fukushima, X Zhang, S Galic, D Briggs, PJ Enriori, S Simonds, ... Cell metabolism 14 (5), 684-699, 2011 | 203 | 2011 |
Whole body deletion of AMP-activated protein kinase β2 reduces muscle AMPK activity and exercise capacity GR Steinberg, HM O'Neill, NL Dzamko, S Galic, T Naim, R Koopman, ... Journal of Biological Chemistry 285 (48), 37198-37209, 2010 | 190 | 2010 |
Small molecule drug A-769662 and AMP synergistically activate naive AMPK independent of upstream kinase signaling JW Scott, N Ling, SMA Issa, TA Dite, MT O’Brien, ZP Chen, S Galic, ... Chemistry & biology 21 (5), 619-627, 2014 | 171 | 2014 |
Deletion of skeletal muscle SOCS3 prevents insulin resistance in obesity SB Jorgensen, HM O’Neill, L Sylow, J Honeyman, KA Hewitt, R Palanivel, ... Diabetes 62 (1), 56-64, 2013 | 170 | 2013 |
Ghrelin-AMPK signaling mediates the neuroprotective effects of calorie restriction in Parkinson's disease JA Bayliss, MB Lemus, R Stark, VV Santos, A Thompson, DJ Rees, ... Journal of Neuroscience 36 (10), 3049-3063, 2016 | 159 | 2016 |
AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice HM O’Neill, JS Lally, S Galic, M Thomas, PD Azizi, MD Fullerton, BK Smith, ... Diabetologia 57, 1693-1702, 2014 | 149 | 2014 |
AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965 TA Dite, CG Langendorf, A Hoque, S Galic, RJ Rebello, AJ Ovens, ... Journal of Biological Chemistry 293 (23), 8874-8885, 2018 | 126 | 2018 |
Liver‐specific suppressor of cytokine signaling‐3 deletion in mice enhances hepatic insulin sensitivity and lipogenesis resulting in fatty liver and obesity 1 N Sachithanandan, BC Fam, S Fynch, N Dzamko, MJ Watt, S Wormald, ... Hepatology 52 (5), 1632-1642, 2010 | 126 | 2010 |
Phosphorylation of acetyl-CoA carboxylase by AMPK reduces renal fibrosis and is essential for the anti-fibrotic effect of metformin M Lee, M Katerelos, K Gleich, S Galic, BE Kemp, PF Mount, DA Power Journal of the American Society of Nephrology 29 (9), 2326-2336, 2018 | 113 | 2018 |
Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms SL Pinkosky, JW Scott, EM Desjardins, BK Smith, EA Day, RJ Ford, ... Nature metabolism 2 (9), 873-881, 2020 | 107 | 2020 |
Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells ex vivo through inhibition of de novo lipogenesis AJ O’Brien, LA Villani, LA Broadfield, VP Houde, S Galic, G Blandino, ... Biochemical Journal 469 (2), 177-187, 2015 | 103 | 2015 |