EPEN-17. IN VITRO MODELLING OF PEDIATRIC SUPRATENTORIAL EPENDYMOMAS USING CEREBRAL ORGANOIDS M Roosen, J Morscio, P Stathi, N Mack, B Schwalm, PA Polychronopoulos, ... Neuro-Oncology 26 (Suppl 4), 0, 2024 | | 2024 |
MDB-68. DISCOVERING DRUG SENSITIVITIES IN MEDULLOBLASTOMA USING PATIENT-AND PDX-DERIVED TUMOROIDS C Meulenbroeks, P Stathi, M van de Wetering, CC Villarejo, N Mack, ... Neuro-Oncology 26 (Suppl 4), 0, 2024 | | 2024 |
ETMR-18. ADVANCING ETMR RESEARCH: NOVELIN VITRO ANDIN VIVO PRECLINICAL MODELS FOR DEVELOPING MORE EFFECTIVE TREATMENTS M Roosen, S Krausert, P Stathi, N Mack, B Schwalm, I Oehme, H Peterziel, ... Neuro-Oncology 26 (Suppl 4), 0, 2024 | | 2024 |
Artificial and natural interventions for chemotherapy-and/or radiotherapy-induced cognitive impairment: A systematic review of animal studies LE Kuil, T Varkevisser, MH Huisman, M Jansen, J Bunt, A Compter, H Ket, ... Neuroscience & Biobehavioral Reviews, 105514, 2023 | 1 | 2023 |
IMMU-53. MONITOR THE IMMUNE MICROENVIRONMENT AND SYSTEMIC IMMUNE EFFECTS IN PEDIATRIC BRAIN TUMORS–THE MIMIC PROGRAM R Hoogendijk, T Carvalheiro, J Lammers, M Kranendonk, ... Neuro-Oncology 25 (Supplement_5), v154-v154, 2023 | | 2023 |
BIOL-11. PRECLINICAL MODELLING OF PEDIATRIC BRAIN TUMORS USING ORGANOID TECHNOLOGY M Roosen, C Meulenbroeks, P Stathi, J Maas, J Morscio, J Bunt, M Kool Neuro-Oncology 25 (Suppl 1), i8, 2023 | | 2023 |
ELUCIDATING THE BIOLOGICAL DIFFERENCE BETWEEN PEDIATRIC SUPRATENTORIAL EPENDYMOMAS USING GENETICALLY ENGINEERED BRAIN TUMOR ORGANOIDS M Roosen, P Stathi, J Bunt, M Kool NEURO-ONCOLOGY 24, 40-40, 2022 | | 2022 |
ETMR-09. In vitro modelling of embryonal tumors with multilayered rosettes (ETMR) and other novel brain tumor types. J Bunt, M Roosen, P Stathi, P Polychronopoulos, Z Odé, J Maas, M Kool Neuro-Oncology 24 (Suppl 1), i51, 2022 | | 2022 |
MEDB-52. Organoids as preclinical models to improve and personalize disease outcome for sonic hedgehog medulloblastoma Z Ode, J Maas, M Roosen, P Stathi, A Federico, N Mack, B Schwalm, ... Neuro-Oncology 24 (Suppl 1), i118, 2022 | | 2022 |
RARE-15. Astroblastoma, MN1 altered comprises two molecularly and clinically distinct subgroups defined by the fusion partners BEND2 and CXXC5 F Schmitt-Hoffner, J Gojo, M Mauermann, K von Hoff, M Sill, D Stichel, ... Neuro-Oncology 24 (Supplement_1), i12-i13, 2022 | 2 | 2022 |
ETMR-06. Molecular and clinical characteristics of CNS tumors withBCOR(L1) fusion/internal tandem duplication J Gojo, F Schmitt-Hoffner, M Mauermann, K von Hoff, M Sill, A Korshunov, ... Neuro-Oncology 24 (Supplement_1), i50-i50, 2022 | 2 | 2022 |
Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruption PW Janowicz, ZH Houston, J Bunt, NL Fletcher, CA Bell, G Cowin, ... Biomaterials 283, 121416, 2022 | 17 | 2022 |
The oncogenic fusion landscape in pediatric CNS neoplasms M Roosen, Z Odé, J Bunt, M Kool Acta Neuropathologica 143 (4), 427-451, 2022 | 29 | 2022 |
EMX2 transcriptionally regulates Nfib expression in neural progenitor cells during early cortical development JWC Lim, J Bunt, CR Bridges, C Moey, MT Jacobs, KS Chen, LJ Richards bioRxiv, 2021.12. 26.474186, 2021 | | 2021 |
GEBTO: GENETICALLY ENGINEERED BRAIN TUMOR ORGANOIDS AS A NOVEL PRECLINICAL MODEL J Bunt, M Roosen, E Egelmeers, J Maas, Z Ode, M Kool NEURO-ONCOLOGY 23, 35-35, 2021 | | 2021 |
DRAXIN regulates interhemispheric fissure remodelling to influence the extent of corpus callosum formation L Morcom, TJ Edwards, E Rider, D Jones-Davis, JWC Lim, KS Chen, ... Elife 10, e61618, 2021 | 11 | 2021 |
NFIA and NFIB function as tumour suppressors in high-grade glioma in mice KS Chen, Z Lynton, JWC Lim, T Robertson, RM Gronostajski, J Bunt, ... Carcinogenesis 42 (3), 357-368, 2021 | 9 | 2021 |
ETMR-13. NFI GENES IN ETMR TUMORIGENESIS AND NEURODEVELOPMENT J Bunt, S Lambo, J Lim, M Mauermann, S Pfister, L Richards, M Kool Neuro-oncology 22 (Suppl 3), iii325, 2020 | | 2020 |
Altered structural connectivity networks in a mouse model of complete and partial dysgenesis of the corpus callosum TJ Edwards, LR Fenlon, RJ Dean, J Bunt, EH Sherr, LJ Richards, ... NeuroImage 217, 116868, 2020 | 17 | 2020 |
Pathogenic DDX3X mutations impair RNA metabolism and neurogenesis during fetal cortical development AL Lennox, ML Hoye, R Jiang, BL Johnson-Kerner, LA Suit, ... Neuron 106 (3), 404-420. e8, 2020 | 151 | 2020 |