Exome-wide evidence of compound heterozygous effects across common phenotypes in the UK Biobank FH Lassen, SS Venkatesh, N Baya, B Hill, W Zhou, A Bloemendal, ... Cell Genomics, 2024 | 1 | 2024 |
Association of Indoleamine 2, 3-Dioxygenase (IDO) Activity with Outcome after Cardiac Surgery in Adult Patients A Stieger, M Huber, Z Yu, BM Kessler, R Fischer, L Andereggen, B Kobel, ... Metabolites 14 (6), 334, 2024 | | 2024 |
Quantitative proteomics reveals CLR interactome in primary human cells D Manolis, S Hasan, A Maraveyas, DP O'Brien, BM Kessler, H Kramer, ... Journal of Biological Chemistry 300 (6), 2024 | | 2024 |
Identification of high-performing antibodies for the reliable detection of Tau proteoforms by Western blotting and immunohistochemistry MJ Ellis, C Lekka, KL Holden, H Tulmin, F Seedat, DP O’Brien, S Dhayal, ... Acta Neuropathologica 147 (1), 87, 2024 | | 2024 |
HSV-1 employs UL56 to antagonize expression and function of cGAMP channels HTW Blest, A Redmond, J Avissar, J Barker, A Bridgeman, G Fowler, ... Cell Reports 43 (5), 2024 | | 2024 |
Proximity proteomics reveals UCH-L1 as an essential regulator of NLRP3-mediated IL-1β production in human macrophages and microglia Z Liang, A Damianou, I Vendrell, E Jenkins, FH Lassen, SJ Washer, ... Cell Reports 43 (5), 2024 | 2 | 2024 |
Deubiquitinases in muscle physiology and disorders CS Olie, DP O'Brien, HBL Jones, Z Liang, A Damianou, I Sur-Erdem, ... Biochemical Society Transactions, BST20230562, 2024 | | 2024 |
Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity MHBA Hamid, PF Cespedes, C Jin, JL Chen, U Gileadi, E Antoun, Z Liang, ... Nature Immunology 25 (5), 834-846, 2024 | 1 | 2024 |
Oncogenic mutations of KRAS modulate its turnover by the CUL3/LZTR1 E3 ligase complex A Damianou, Z Liang, F Lassen, I Vendrell, G Vere, S Hester, PD Charles, ... Life Science Alliance 7 (5), 2024 | | 2024 |
Kidney Tissue Proteome Profiles in Short Versus Long Duration of Delayed Graft Function-A Pilot Study in Donation After Circulatory Death Donors MLL Faro, K Rozenberg, H Huang, S Maslau, S Bonham, R Fischer, ... Kidney International Reports 9 (5), 1473-1483, 2024 | | 2024 |
Type I interferon regulation by USP18 is a key vulnerability in cancer V Jové, H Wheeler, CW Lee, DR Healy, K Levine, EC Ralph, ... Iscience 27 (4), 2024 | 1 | 2024 |
Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C-terminal Hydrolase L1 RD Imhoff, R Patel, MH Safdar, HBL Jones, A Pinto-Fernandez, I Vendrell, ... Journal of Medicinal Chemistry 67 (6), 4496-4524, 2024 | | 2024 |
BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution K Tsukada, SE Jones, J Bannister, MA Durin, I Vendrell, M Fawkes, ... Molecular Cell 84 (4), 640-658. e10, 2024 | 2 | 2024 |
Data‐independent acquisition proteomics of cerebrospinal fluid implicates endoplasmic reticulum and inflammatory mechanisms in amyotrophic lateral sclerosis ER Dellar, I Vendrell, K Talbot, BM Kessler, R Fischer, MR Turner, ... Journal of Neurochemistry 168 (2), 115-127, 2024 | 2 | 2024 |
Targeted delivery of galunisertib using machine perfusion reduces fibrogenesis in an integrated ex vivo renal transplant and fibrogenesis model LL van Leeuwen, MJR Ruigrok, BM Kessler, HGD Leuvenink, P Olinga British Journal of Pharmacology 181 (3), 464-479, 2024 | 4 | 2024 |
Syncytiotrophoblast extracellular vesicles contain functional kynurenine metabolising enzymes: potential implications for preeclampsia. PV Logenthiran, TA Awoyemi, M Wilbourne, Z Yu, B Kessler, C Escudero, ... medRxiv, 2024.05. 25.24307626, 2024 | | 2024 |
A systems-based approach to uterine fibroids identifies differential splicing associated with abnormal uterine bleeding CY Wang, M Philpott, DP O'Brien, AP Ndungu, J Malzahn, M Maritati, ... bioRxiv, 2024.02. 06.578872, 2024 | | 2024 |
Discovery of plasma proteome markers associated with clinical outcome and immunological stress after cardiac surgery C Bello, MG Filipovic, M Huber, S Flannery, B Kobel, R Fischer, ... Frontiers in cardiovascular medicine 10, 1287724, 2023 | 1 | 2023 |
USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism J Gan, A Pinto-Fernández, D Flierman, JJLL Akkermans, DP O’Brien, ... Proceedings of the National Academy of Sciences 120 (50), e2315163120, 2023 | 5 | 2023 |
Deep topographic proteomics of a human brain tumour S Davis, C Scott, J Oetjen, PD Charles, BM Kessler, O Ansorge, R Fischer Nature Communications 14 (1), 7710, 2023 | 4 | 2023 |