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Lynne Postovit
Lynne Postovit
Verified email at queensu.ca
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Cited by
Year
Preclinical 3D model screening reveals digoxin as an effective therapy for a rare and aggressive type of endometrial cancer
PP Kumar, DP Smith, J Key, H Dong, A Ganapathysamy, V Maranda, ...
Gynecologic Oncology 188, 162-168, 2024
2024
Targeted proteomics of plasma extracellular vesicles uncovers MUC1 as combinatorial biomarker for the early detection of high-grade serous ovarian cancer
TT Cooper, DZ Dieters-Castator, J Liu, GM Siegers, D Pink, L Veliz, ...
Journal of Ovarian Research 17 (1), 149, 2024
2024
Multiomics analysis identifies oxidative phosphorylation as a cancer vulnerability arising from myristoylation inhibition
E Beauchamp, JM Gamma, CR Cromwell, EW Moussa, R Pain, ...
Journal of Translational Medicine 22 (1), 431, 2024
22024
Correction: MNK1/NODAL Signaling Promotes Invasive Progression of Breast Ductal Carcinoma In Situ
Q Guo, VZ Li, JN Nichol, F Huang, W Yang, SEJ Preston, Z Talat, ...
Cancer Research 84 (8), 1373-1373, 2024
2024
Transcription factor ZIC2 regulates the tumorigenic phenotypes associated with both bulk and cancer stem cells in epithelial ovarian cancer
H Chen, LJ Lee, KM Vincent, Z Xu, J Liu, G Zhang, Z Nakevska, DP Smith, ...
Oncogene, 1-13, 2024
2024
MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors
HE Kim, B Lebeau, D Papadopoli, P Jovanovic, M Russo, D Avizonis, ...
Iscience 27 (3), 2024
2024
Cancer-associated Fibroblast–specific Expression of the Matricellular Protein CCN1 Coordinates Neovascularization and Stroma Deposition in Melanoma Metastasis
J Hutchenreuther, J Nguyen, K Quesnel, KM Vincent, L Petitjean, ...
Cancer Research Communications 4 (2), 556-570, 2024
42024
Tandem SERS and MS/MS Profiling of Plasma Extracellular Vesicles for Early Ovarian Cancer Biomarker Discovery
L Veliz, TT Cooper, I Grenier-Pleau, SA Abraham, J Gomes, SH Pasternak, ...
ACS sensors 9 (1), 272-282, 2024
22024
Wounding the stroma: Docetaxel’s role in dormant breast cancer escape
TT Cooper, LM Postovit
PLoS Biology 21 (9), e3002297, 2023
2023
Establishment and validation of preclinical models of SMARCA4-inactivated and ARID1A/ARID1B co-inactivated dedifferentiated endometrial carcinoma
NKY Wong, ML Fernandez, FKF Kommoss, PP Kumar, H Kim, J Liu, ...
Gynecologic Oncology 176, 162-172, 2023
12023
RNA cytosine methyltransferase NSUN5 promotes protein synthesis and tumorigenic phenotypes in glioblastoma
J Zhou, YS Kong, KM Vincent, D Dieters‐Castator, AB Bukhari, ...
Molecular Oncology 17 (9), 1763-1783, 2023
22023
Tailoring 3′ UTRs alters metastatic potential
K Watt, LM Postovit
Nature Cell Biology 25 (6), 805-807, 2023
2023
Epigenetic coordination of transcriptional and translational programs in hypoxia
K Watt, B Dauber, KJ Szkop, L Lee, P Jovanovic, S Chen, L Masvidal, ...
bioRxiv, 2023.09. 16.558067, 2023
12023
Fibroblast-specific expression of the proangiogenic protein CCN1 is linked to checkpoint inhibitor resistance in melanoma
J Hutchenreuther, K Vincent, J Nguyen, LM Postovit, A Leask
WOUND REPAIR AND REGENERATION 30 (5), A27-A27, 2022
2022
Docosahexaenoic acid enrichment of tumor phospholipid membranes increases tumor necroptosis in mice bearing triple negative breast cancer patient-derived xenografts
M Newell, S Goruk, J Schueler, V Mazurak, LM Postovit, CJ Field
The Journal of Nutritional Biochemistry 107, 109018, 2022
92022
Phosphorylation of eIF4E in the stroma drives the production and spatial organisation of collagen type I in the mammary gland
SEJ Preston, M Bartish, VR Richard, A Aghigh, C Goncalves, ...
Matrix Biology 111, 264-288, 2022
112022
Targeting N-myristoylation for therapy of adult acute myeloid leukemia
J Gamma, A Iyer, M Yap, Z Zak, K Vincent, C Ekstrom, Q Liu, ...
Cancer Research 82 (12_Supplement), 5662-5662, 2022
2022
Docosahexaenoic acid in the inhibition of tumor cell growth in preclinical models of ovarian cancer
O Bilyk, B Hamedi, I Dutta, M Newell, AB Bukhari, AM Gamper, RC McVea, ...
Nutrition and Cancer 74 (4), 1431-1445, 2022
82022
Targeted Proteomics and Support Vector Classification Reveal Potential Biomarkers for the Early Detection of High-grade Serous Ovarian Cancer
TT Cooper, DZ Dieters-Castator, J Liu, GM Siegers, D Pink, JD Lewis, ...
2022
Validation of NMT1 and NMT2 as novel drug targets in adult acute myeloid leukemia: Rationale for N-myristoyltransferase inhibition with Pclx-001 for clinical trials
J Gamma, A Iyer, M Yap, Z Zak, K Vincent, C Ekstrom, E Beauchamp, ...
Blood 138 (Supplement 1), 4344-4344, 2021
12021
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