Preclinical 3D model screening reveals digoxin as an effective therapy for a rare and aggressive type of endometrial cancer PP Kumar, DP Smith, J Key, H Dong, A Ganapathysamy, V Maranda, ... Gynecologic Oncology 188, 162-168, 2024 | | 2024 |
Targeted proteomics of plasma extracellular vesicles uncovers MUC1 as combinatorial biomarker for the early detection of high-grade serous ovarian cancer TT Cooper, DZ Dieters-Castator, J Liu, GM Siegers, D Pink, L Veliz, ... Journal of Ovarian Research 17 (1), 149, 2024 | | 2024 |
Multiomics analysis identifies oxidative phosphorylation as a cancer vulnerability arising from myristoylation inhibition E Beauchamp, JM Gamma, CR Cromwell, EW Moussa, R Pain, ... Journal of Translational Medicine 22 (1), 431, 2024 | 2 | 2024 |
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Transcription factor ZIC2 regulates the tumorigenic phenotypes associated with both bulk and cancer stem cells in epithelial ovarian cancer H Chen, LJ Lee, KM Vincent, Z Xu, J Liu, G Zhang, Z Nakevska, DP Smith, ... Oncogene, 1-13, 2024 | | 2024 |
MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors HE Kim, B Lebeau, D Papadopoli, P Jovanovic, M Russo, D Avizonis, ... Iscience 27 (3), 2024 | | 2024 |
Cancer-associated Fibroblast–specific Expression of the Matricellular Protein CCN1 Coordinates Neovascularization and Stroma Deposition in Melanoma Metastasis J Hutchenreuther, J Nguyen, K Quesnel, KM Vincent, L Petitjean, ... Cancer Research Communications 4 (2), 556-570, 2024 | 4 | 2024 |
Tandem SERS and MS/MS Profiling of Plasma Extracellular Vesicles for Early Ovarian Cancer Biomarker Discovery L Veliz, TT Cooper, I Grenier-Pleau, SA Abraham, J Gomes, SH Pasternak, ... ACS sensors 9 (1), 272-282, 2024 | 2 | 2024 |
Wounding the stroma: Docetaxel’s role in dormant breast cancer escape TT Cooper, LM Postovit PLoS Biology 21 (9), e3002297, 2023 | | 2023 |
Establishment and validation of preclinical models of SMARCA4-inactivated and ARID1A/ARID1B co-inactivated dedifferentiated endometrial carcinoma NKY Wong, ML Fernandez, FKF Kommoss, PP Kumar, H Kim, J Liu, ... Gynecologic Oncology 176, 162-172, 2023 | 1 | 2023 |
RNA cytosine methyltransferase NSUN5 promotes protein synthesis and tumorigenic phenotypes in glioblastoma J Zhou, YS Kong, KM Vincent, D Dieters‐Castator, AB Bukhari, ... Molecular Oncology 17 (9), 1763-1783, 2023 | 2 | 2023 |
Tailoring 3′ UTRs alters metastatic potential K Watt, LM Postovit Nature Cell Biology 25 (6), 805-807, 2023 | | 2023 |
Epigenetic coordination of transcriptional and translational programs in hypoxia K Watt, B Dauber, KJ Szkop, L Lee, P Jovanovic, S Chen, L Masvidal, ... bioRxiv, 2023.09. 16.558067, 2023 | 1 | 2023 |
Fibroblast-specific expression of the proangiogenic protein CCN1 is linked to checkpoint inhibitor resistance in melanoma J Hutchenreuther, K Vincent, J Nguyen, LM Postovit, A Leask WOUND REPAIR AND REGENERATION 30 (5), A27-A27, 2022 | | 2022 |
Docosahexaenoic acid enrichment of tumor phospholipid membranes increases tumor necroptosis in mice bearing triple negative breast cancer patient-derived xenografts M Newell, S Goruk, J Schueler, V Mazurak, LM Postovit, CJ Field The Journal of Nutritional Biochemistry 107, 109018, 2022 | 9 | 2022 |
Phosphorylation of eIF4E in the stroma drives the production and spatial organisation of collagen type I in the mammary gland SEJ Preston, M Bartish, VR Richard, A Aghigh, C Goncalves, ... Matrix Biology 111, 264-288, 2022 | 11 | 2022 |
Targeting N-myristoylation for therapy of adult acute myeloid leukemia J Gamma, A Iyer, M Yap, Z Zak, K Vincent, C Ekstrom, Q Liu, ... Cancer Research 82 (12_Supplement), 5662-5662, 2022 | | 2022 |
Docosahexaenoic acid in the inhibition of tumor cell growth in preclinical models of ovarian cancer O Bilyk, B Hamedi, I Dutta, M Newell, AB Bukhari, AM Gamper, RC McVea, ... Nutrition and Cancer 74 (4), 1431-1445, 2022 | 8 | 2022 |
Targeted Proteomics and Support Vector Classification Reveal Potential Biomarkers for the Early Detection of High-grade Serous Ovarian Cancer TT Cooper, DZ Dieters-Castator, J Liu, GM Siegers, D Pink, JD Lewis, ... | | 2022 |
Validation of NMT1 and NMT2 as novel drug targets in adult acute myeloid leukemia: Rationale for N-myristoyltransferase inhibition with Pclx-001 for clinical trials J Gamma, A Iyer, M Yap, Z Zak, K Vincent, C Ekstrom, E Beauchamp, ... Blood 138 (Supplement 1), 4344-4344, 2021 | 1 | 2021 |