Design, Synthesis, and Evaluation of New 1H-Benzo[d]imidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections F Soukarieh, A Mashabi, W Richardson, EV Oton, M Romero, JF Dubern, ... Journal of Medicinal Chemistry 67 (2), 1008-1023, 2024 | | 2024 |
Polymer-coated urinary catheter reduces biofilm formation and biomineralization: a first-in-man, prospective pilot study K Kalenderski, JF Dubern, C Lewis-Lloyd, N Jeffery, S Heeb, DJ Irvine, ... JU Open Plus 2 (1), e00005, 2024 | 1 | 2024 |
RsaL-driven negative regulation promotes heterogeneity in Pseudomonas aeruginosa quorum sensing M Mellini, M Letizia, L Caruso, A Guiducci, C Meneghini, S Heeb, ... Mbio 14 (6), e02039-23, 2023 | 2 | 2023 |
Toward Comprehensive Analysis of the 3D Chemistry of Pseudomonas aeruginosa Biofilms AM Kotowska, J Zhang, A Carabelli, J Watts, JW Aylott, IS Gilmore, ... Analytical Chemistry 95 (49), 18287-18294, 2023 | 1 | 2023 |
CD206 upregulation in monocytes within whole blood cultures correlates with lung function in Cystic Fibrosis: a pilot study S Singh, J Longmate, D Onion, P Williams, M Camara, AR Smyth, H Barr, ... medRxiv, 2023.11. 15.23298577, 2023 | | 2023 |
Modelled-Microgravity Reduces Virulence Factor Production in Staphylococcus aureus through Downregulation of agr-Dependent Quorum Sensing MJ Green, EJ Murray, P Williams, AM Ghaemmaghami, JW Aylott, ... International Journal of Molecular Sciences 24 (21), 15997, 2023 | 1 | 2023 |
Reciprocal regulation of NagC and quorum sensing systems and their roles in hmsHFRS expression and biofilm formation in Yersinia pseudotuberculosis. AS Wiechmann A, Garcia V, Elton L, Williams P Microbiology (Reading) 169 (10), 001397., 2023 | | 2023 |
Quorum-sensing, intra-and inter-species competition in the staphylococci P Williams, P Hill, B Bonev, WC Chan Microbiology 169 (8), 001381, 2023 | 11 | 2023 |
Alkyl-quinolone-dependent quorum sensing controls prophage-mediated autolysis in Pseudomonas aeruginosa colony biofilms G Giallonardi, M Letizia, M Mellini, E Frangipani, N Halliday, S Heeb, ... Frontiers in Cellular and Infection Microbiology 13, 1183681, 2023 | 5 | 2023 |
Conformational analysis and interaction of the Staphylococcus aureus transmembrane peptidase AgrB with its AgrD propeptide substrate P Bardelang, EJ Murray, I Blower, S Zandomeneghi, A Goode, R Hussain, ... Frontiers in Chemistry 11, 1113885, 2023 | 9 | 2023 |
Identification of Pseudomonas aeruginosa exopolysaccharide Psl in biofilms using 3D OrbiSIMS H Khateb, AL Hook, S Kern, JA Watts, S Singh, D Jackson, ... Biointerphases 18 (3), 2023 | 2 | 2023 |
Shapeshifting bullvalene-linked vancomycin dimers as effective antibiotics against multidrug-resistant gram-positive bacteria A Ottonello, JA Wyllie, O Yahiaoui, S Sun, RA Koelln, JA Homer, ... Proceedings of the National Academy of Sciences 120 (15), e2208737120, 2023 | 9 | 2023 |
Growth rate and nutrient limitation as key drivers of extracellular quorum sensing signal molecule accumulation in Pseudomonas aeruginosa JF Dubern, N Halliday, M Cámara, K Winzer, DA Barrett, KR Hardie, ... Microbiology 169 (4), 001316, 2023 | 3 | 2023 |
Linear Binary Classifier to Predict Bacterial Biofilm Formation on Polyacrylates L Contreas, AL Hook, DA Winkler, G Figueredo, P Williams, CA Laughton, ... ACS Applied Materials & Interfaces 15 (11), 14155-14163, 2023 | 5 | 2023 |
Exploring the Relationship between Polymer Surface Chemistry and Bacterial Attachment Using ToF‐SIMS and Self‐Organizing maps SY Wong, AL Hook, W Gardner, CY Chang, Y Mei, MC Davies, P Williams, ... Advanced Materials Interfaces 10 (9), 2202334, 2023 | 3 | 2023 |
Discovery of a polymer resistant to bacterial biofilm, swarming, and encrustation JF Dubern, AL Hook, AM Carabelli, CY Chang, CA Lewis-Lloyd, ... Science Advances 9 (4), eadd7474, 2023 | 15 | 2023 |
Predictive Molecular Design and Structure–Property Validation of Novel Terpene-Based, Sustainably Sourced Bacterial Biofilm-Resistant Materials V Cuzzucoli Crucitti, A Ilchev, JC Moore, HR Fowler, JF Dubern, O Sanni, ... Biomacromolecules 24 (2), 576-591, 2023 | 5 | 2023 |
Mushroom‐shaped structures formed in Acinetobacter baumannii biofilms grown in a roller bioreactor are associated with quorum sensing–dependent Csu‐pilus … M Romero, C Mayer, S Heeb, K Wattanavaekin, M Cámara, A Otero, ... Environmental Microbiology 24 (9), 4329-4339, 2022 | 15 | 2022 |
ToxR is a c-di-GMP binding protein that modulates surface-associated behaviour in Pseudomonas aeruginosa JF Dubern, M Romero, A Mai-Prochnow, M Messina, E Trampari, ... npj Biofilms and Microbiomes 8 (1), 64, 2022 | 7 | 2022 |
A Pseudomonas aeruginosa PQS quorum-sensing system inhibitor with anti-staphylococcal activity sensitizes polymicrobial biofilms to tobramycin EJ Murray, JF Dubern, WC Chan, SR Chhabra, P Williams Cell chemical biology 29 (7), 1187-1199. e6, 2022 | 24 | 2022 |