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Robert A. Holt
Robert A. Holt
Head of Sequencing, Michael Smith Genome Sciences Centre, BC Cancer Agency Distinguished Scientist
Verified email at bcgsc.ca - Homepage
Title
Cited by
Year
Immune checkpoint therapy responders display early clonal expansion of tumor infiltrating lymphocytes
J Kidman, RM Zemek, JW Sidhom, D Correa, N Principe, F Sheikh, ...
Oncoimmunology 13 (1), 2345859, 2024
22024
Direct in vivo CAR T cell engineering
L Short, RA Holt, PR Cullis, L Evgin
Trends in Pharmacological Sciences, 2024
32024
Discovery and preclinical development of a therapeutically active nanobody-based chimeric antigen receptor targeting human CD22
S McComb, M Arbabi-Ghahroudi, KA Hay, BA Keller, S Faulkes, ...
Molecular Therapy Oncology 32 (1), 2024
12024
A Synthetic Cytotoxic T cell Platform for Rapidly Prototyping TCR Function
G Sharma, J Round, F Teng, Z Ali, C May, E Yung, RA Holt
bioRxiv, 2023
2023
Plasmonically coupled semiconductor quantum dots for efficient hydrogen photoelectrocatalysis
M Ijaz, H Zhang, SV Chan, R Holt, NJLK Davis, RJ Blaikie
Applied Physics Letters 123 (5), 2023
72023
Behavioral dissection of hunger states in Drosophila
KJ Weaver, S Raju, RA Rucker, T Chakraborty, RA Holt, SD Pletcher
Elife 12, RP84537, 2023
22023
Author Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
I Cortés-Ciriano, JJK Lee, R Xi, D Jain, YL Jung, L Yang, D Gordenin, ...
nature genetics 55 (6), 1076-1076, 2023
22023
Effects of hunger on neuronal histone modifications slow aging in Drosophila
KJ Weaver, RA Holt, E Henry, Y Lyu, SD Pletcher
Science 380 (6645), 625-632, 2023
182023
Complete sequence verification of plasmid DNA using the Oxford Nanopore Technologies’ MinION device
SD Brown, L Dreolini, JF Wilson, M Balasundaram, RA Holt
BMC bioinformatics 24 (1), 116, 2023
112023
Immune activation following Irbesartan treatment in a colorectal cancer patient: a case study
E Titmuss, K Milne, MR Jones, T Ng, JT Topham, SD Brown, DF Schaeffer, ...
International Journal of Molecular Sciences 24 (6), 5869, 2023
12023
Author Correction: Pan-cancer analysis of whole genomes
Nature 614 (7948), E39-E39, 2023
12023
Oncomicrobial vaccines: the potential for a Fusobacterium nucleatum vaccine to improve colorectal cancer outcomes
RA Holt
Cell Host & Microbe 31 (1), 141-145, 2023
112023
Author Correction: Pan-cancer analysis of whole genomes (Nature,(2020), 578, 7793,(82-93), 10.1038/s41586-020-1969-6)
LA Aaltonen, F Abascal, A Abeshouse, H Aburatani, DJ Adams, ...
Nature 614 (7948), E39, 2023
2023
CLIC-01: Manufacture and distribution of non-cryopreserved CAR-T cells for patients with CD19 positive hematologic malignancies
N Kekre, KA Hay, JR Webb, R Mallick, JS Nielsen, J Quizi, SD Brown, ...
Frontiers in immunology 13, 1074740, 2022
102022
Selective B cell depletion upon intravenous infusion of replication-incompetent anti-CD19 CAR lentivirus
CM Rive, E Yung, L Dreolini, SD Brown, CG May, DJ Woodsworth, ...
Molecular Therapy Methods & Clinical Development 26, 4-14, 2022
92022
Encoding of hunger by the neuronal epigenome slows aging in Drosophila
KJ Weaver, RA Holt, E Henry, SD Pletcher
Biorxiv, 2022.07. 21.501022, 2022
22022
Early Clonal Expansion of Tumour-Infiltrating Lymphocytes Predicts Response to Immune Checkpoint Therapy
J Kidman, R Zemek, JW Sidhom, D Correa, N Principe, F Sheikh, VS Fear, ...
2022
Fusobacterium nucleatum and Bacteroides fragilis detection in colorectal tumours: Optimal target site and correlation with total bacterial load
MS Rye, KL Garrett, RA Holt, CF Platell, MJ McCoy
Plos one 17 (1), e0262416, 2022
82022
Tumor Antigen-Specific Infiltrating CD8+ Effector T Cells Memory Predict Response to Immune Checkpoint Therapy
N Principe, J Kidman, S Goh, CM Tilsed, SA Fisher, VS Fear, CA Forbes, ...
Dynamic Biomarkers of Response to Anti-Immune Checkpoint Inhibitors in Cancer, 2021
2021
Clinical response to nivolumab in an INI1-deficient pediatric chordoma correlates with immunogenic recognition of brachyury
LM Williamson, CM Rive, D Di Francesco, E Titmuss, HJE Chun, ...
NPJ Precision Oncology 5 (1), 103, 2021
272021
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