| Withdrawal: Lysophosphatidic acid stimulates the G-protein-coupled receptor EDG-1 as a low affinity agonist MJ Lee, S Thangada, CH Liu, BD Thompson, T Hla Journal of Biological Chemistry 300 (8), 2024 | | 2024 |
| Regulation of cellular and systemic sphingolipid homeostasis A Kuo, T Hla Nature Reviews Molecular Cell Biology, 1-20, 2024 | 1 | 2024 |
| Endothelial cell sphingosine 1-phosphate receptor 1 restrains VE-cadherin cleavage and attenuates experimental inflammatory arthritis N Burg, R Malpass, L Alex, M Tran, E Englebrecht, A Kuo, T Pannelini, ... JCI insight 9 (11), 2024 | 1 | 2024 |
| The sphinx helps to answer the riddle of cardiac regeneration JW Jung, T Hla, Z Arany Trends in Endocrinology & Metabolism, 2024 | | 2024 |
| Pyridinone-and pyridazinone-based compounds and uses thereof T Hla, I Jilishitz, P Meinke, A Stamford, M Foley, A Sato, Y Wada, ... US Patent 11,964,960, 2024 | | 2024 |
| The β-catenin C terminus links Wnt and sphingosine-1-phosphate signaling pathways to promote vascular remodeling and atherosclerosis GH Oliveira-Paula, S Liu, A Maira, G Ressa, GC Ferreira, A Quintar, ... Science Advances 10 (11), eadg9278, 2024 | 1 | 2024 |
| Designer high-density lipoprotein particles enhance endothelial barrier function and suppress inflammation YC Lin, S Swendeman, IS Moreira, A Ghosh, A Kuo, N Rosário-Ferreira, ... Science signaling 17 (824), eadg9256, 2024 | 1 | 2024 |
| Augmentation of endothelial S1PR1 attenuates postviral pulmonary fibrosis PL Brazee, A Cartier, A Kuo, AM Haring, T Nguyen, LP Hariri, JW Griffith, ... American Journal of Respiratory Cell and Molecular Biology 70 (2), 119-128, 2024 | 2 | 2024 |
| Sphingosine kinase 1 is integral for elastin deficiency-induced arterial hypermuscularization J Saito, JM Dave, E Gallardo-Vara, I Kabir, G Tellides, RK Riemer, ... bioRxiv, 2024.07. 01.601150, 2024 | | 2024 |
| Report from the 2023 workshop on endothelial permeability, edema and inflammation D Vestweber, L Claesson-Welsh, DM McDonald, T Williams, MA Schwartz, ... Nature Cardiovascular Research 2 (12), 1120-1124, 2023 | | 2023 |
| Dependence of IL-7R-Mediated Signaling on Sphingosine Kinase Activity in Acute Lymphoblastic Leukemia, but Not Healthy Lymphoid Cells, Is an Exploitable Therapeutic Vulnerability MB Fernandes, A Melão, T Araújo, A Cachucho, DR Adams, J Oh, ... Blood 142, 38, 2023 | | 2023 |
| Beta-catenin C-terminus inhibition reduces vascular remodeling by precluding the expression of sphingosine-1-phosphate receptor-1 GO de Paula, G Ressa, V Almonte, D Parikh, T Valenta, K Basler, T Hla, ... Journal of Pharmacology and Experimental Therapeutics 385 (S3), 2023 | | 2023 |
| Therapeutic activation of endothelial sphingosine‐1‐phosphate receptor 1 by chaperone‐bound S1P suppresses proliferative retinal neovascularization C Niaudet, B Jung, A Kuo, S Swendeman, E Bull, T Seno, R Crocker, Z Fu, ... EMBO Molecular Medicine 15 (5), e16645, 2023 | 8 | 2023 |
| Beta-catenin C-terminus Signaling Drives Sphingosine-1-phosphate Receptor-1 Expression in Smooth Muscle Cells to Promote Vascular Remodeling GH Oliveira de Paula, G Ressa, S Jayakumar, V Almonte, D Parikh, ... Arteriosclerosis, Thrombosis, and Vascular Biology 43 (Suppl_1), A367-A367, 2023 | | 2023 |
| Signal transduction and gene regulation in the endothelium MV Levesque, T Hla Cold Spring Harbor perspectives in medicine 13 (1), 2023 | 1 | 2023 |
| 1206 Sphingosine 1-phosphate (S1P) regulation of vascular and immune systems: Mechanisms and therapeutic approaches T Hla Lupus Science & Medicine 9 (Suppl 3), 2022 | | 2022 |
| Murine endothelial serine palmitoyltransferase 1 (SPTLC1) is required for vascular development and systemic sphingolipid homeostasis A Kuo, A Checa, C Niaudet, B Jung, Z Fu, CE Wheelock, SA Singh, ... Elife 11, e78861, 2022 | 8 | 2022 |
| MicroRNA 33A controls SREBP-2 and LXR dependent regulation of the LDL receptor pathway V Ramachandran, M Modder, L Zhang, C Krumm, WIH Panhuis, ... Atherosclerosis 355, 73, 2022 | | 2022 |
| Sphingosine 1-phosphate receptor 1 regulates cell-surface localization of membrane proteins in endothelial cells (vol 1863, pg 1079, 2019) X Shia, W Wang, J Li, T Wang, Y Lin, S Huang, A Kuver, C Chen, T Hla, ... BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1866 (8), 2022 | | 2022 |
| DOCK4 regulation of Rho GTPases mediates pulmonary vascular barrier function P Yazbeck, X Cullere, P Bennett, V Yajnik, H Wang, K Kawada, VM Davis, ... Arteriosclerosis, thrombosis, and vascular biology 42 (7), 886-902, 2022 | 3 | 2022 |
Richard L ProiaNIDDK/NIHVerified email at nih.gov