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Gosia Trynka
Gosia Trynka
Group leader
Verified email at sanger.ac.uk - Homepage
Title
Cited by
Year
AI and immunology
RN Germain, EM Van Allen, G Trynka, JS Tsang, D Grün, AL Kiemen, ...
Immunity 57 (6), 1177-1181, 2024
2024
NUDCD3 deficiency disrupts V(D)J recombination to cause SCID and Omenn syndrome
R Chen, E Lukianova, IS van der Loeff, JS Spegarova, JDP Willet, ...
Science Immunology 9 (95), eade5705, 2024
2024
Human Genetics and Genomics for Drug Target Identification and Prioritization: Open Targets’ Perspective
EM McDonagh, G Trynka, M McCarthy, ER Holzinger, S Khader, N Nakic, ...
Annual Review of Biomedical Data Science 7, 2024
2024
An atlas of protein-protein associations of human tissues prioritizes candidate disease genes
DS Laman Trip, M van Oostrum, D Memon, F Frommelt, D Baptista, ...
bioRxiv, 2024.05. 15.594301, 2024
2024
Arrayed screening of immune disease associated genes identifies modulators of CD4+ regulatory T cell suppression
O Bakker, G Griffiths, B Soskic, K Maratou, M Bartholomew, J Smith, ...
EUROPEAN JOURNAL OF HUMAN GENETICS 32, 450-450, 2024
2024
Single cell expression, surface proteins, and T and B cell receptor usage in a multi ancestry systemic lupus erythematosus cohort
N de Klein, T Rupall, B Chau, W Lee, H Jang, S Eastham, N Buang, ...
EUROPEAN JOURNAL OF HUMAN GENETICS 32, 19-19, 2024
2024
Single-cell transcriptomics defines an improved, validated monoculture protocol for differentiation of human iPSC to microglia
SJ Washer, M Perez-Alcantara, Y Chen, J Steer, WS James, G Trynka, ...
Scientific Reports 12 (1), 19454, 2022
192022
Genetic variants associated with psychiatric disorders are enriched at epigenetically active sites in lymphoid cells
ME Lynall, B Soskic, J Hayhurst, J Schwartzentruber, DF Levey, ...
Nature communications 13 (1), 6102, 2022
202022
Research briefing
PA Sossi
2022
A molecular map of T cell activation gives insights into immune disease
B Soskic, G Trynka
NATURE GENETICS 54 (6), 752-753, 2022
2022
Immune disease risk variants regulate gene expression dynamics during CD4+ T cell activation
B Soskic, E Cano-Gamez, DJ Smyth, K Ambridge, Z Ke, JC Matte, ...
Nature genetics 54 (6), 817-826, 2022
712022
Robust temporal map of human in vitro myelopoiesis using single-cell genomics
C Alsinet, MN Primo, V Lorenzi, E Bello, I Kelava, CP Jones, ...
Nature communications 13 (1), 2885, 2022
192022
Immune disease variants modulate gene expression in regulatory CD4+ T cells
L Bossini-Castillo, DA Glinos, N Kunowska, G Golda, AA Lamikanra, ...
Cell genomics 2 (4), 2022
252022
Genetic variants associated with cross-disorder and disorder-specific risk for psychiatric disorders are enriched at epigenetically active sites in peripheral lymphoid cells
ME Lynall, B Soskic, J Hayhurst, J Schwartzentruber, DF Levey, ...
medRxiv, 2021.08. 04.21261606, 2021
52021
Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney
JM Eales, X Jiang, X Xu, S Saluja, A Akbarov, E Cano-Gamez, ...
Nature genetics 53 (5), 630-637, 2021
472021
Hypertension and renin-angiotensin system blockers are not associated with expression of angiotensin-converting enzyme 2 (ACE2) in the kidney
X Jiang, JM Eales, D Scannali, A Nazgiewicz, P Prestes, M Maier, ...
European heart journal 41 (48), 4580-4588, 2020
502020
Functional studies of GWAS variants are gaining momentum
F Lichou, G Trynka
Nature communications 11 (1), 6283, 2020
542020
Genomic profiling of T-cell activation suggests increased sensitivity of memory T cells to CD28 costimulation
DA Glinos, B Soskic, C Williams, A Kennedy, L Jostins, DM Sansom, ...
Genes & Immunity 21 (6), 390-408, 2020
292020
Perspectives on ENCODE
F Abascal, R Acosta, NJ Addleman, J Adrian, V Afzal, B Aken, JA Akiyama
Nature 583 (7818), 693-699, 2020
252020
A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cells
R Nasrallah, CJ Imianowski, L Bossini-Castillo, FM Grant, M Dogan, ...
Nature 583 (7816), 447-452, 2020
502020
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Articles 1–20