Molecular analyses of glaucomatous trabecular meshwork cells harboring the N700S thrombospondin-1 variant KE Keller, YF Yang, YY Sun, J Murphy-Ullrich, P Holden Investigative Ophthalmology & Visual Science 65 (7), 3553-3553, 2024 | | 2024 |
Profiling IOP-Responsive Genes in Anterior and Posterior Ocular Tissues following a Controlled Elevation of IOP. DC Lozano, KE Keller, YF Yang, E Ing, WO Cepurna, JC Morrison Investigative Ophthalmology & Visual Science 65 (7), 3548-3548, 2024 | | 2024 |
Transcriptomic and epigenomic profiling of normal and glaucomatous trabecular meshwork cells in a tissue-like soft ECM environment S Herberg, R Ghosh, R Hadvina, A Singh, DW Stamer, KE Keller, ... Investigative Ophthalmology & Visual Science 65 (7), 5172-5172, 2024 | | 2024 |
Prolonged ECM stiffening induces a glaucoma-like phenotype in trabecular meshwork cells through mechanical memory retention R Ghosh, S Patel, I Salama, MP Geiss, S Ghosh, KE Keller, PS Ganapathy, ... Investigative Ophthalmology & Visual Science 65 (7), 6463-6463, 2024 | | 2024 |
Identifying nuclear alterations in Schlemm’s canal cells interacting with glaucomatous trabecular meshwork cells using a 3D ECM hydrogel co-culture model A Singh, S Patel, R Ghosh, AN Strat, R Hadvina, KM Perkumas, ... Investigative Ophthalmology & Visual Science 65 (7), 5152-5152, 2024 | | 2024 |
Effects of aging and NFATc1 activation on TGFβ2, β3 integrin and EDA+/EDB+ fibronectin isoforms in human trabecular meshwork (HTM) cells J Faralli, KL Johns, MS Filla, KE Keller, DM Peters Investigative Ophthalmology & Visual Science 65 (7), 5165-5165, 2024 | | 2024 |
Thrombospondin-1 is a novel substrate for matrix metalloproteinase-1 (MMP-1) P Holden, J Murphy-Ullrich, YF Yang, YY Sun, KE Keller Investigative Ophthalmology & Visual Science 65 (7), 3577-3577, 2024 | | 2024 |
Effects of 3D mechanical stretch on trabecular meshwork cell nuclear morphology and genome-wide expression patterns KK Palanivel, S Patel, R Hadvina, KE Keller, Y Liu, PS Ganapathy, ... Investigative Ophthalmology & Visual Science 65 (7), 5166-5166, 2024 | | 2024 |
Profiling IOP-Responsive Genes in the Trabecular Meshwork and Optic Nerve Head in a Rat Model of Controlled Elevation of Intraocular Pressure DC Lozano, YF Yang, WO Cepurna, BF Smoody, E Ing, JC Morrison, ... Investigative Ophthalmology & Visual Science 65 (5), 41-41, 2024 | | 2024 |
Digital spatial profiling of segmental outflow regions in trabecular meshwork reveals a role for ADAM15 JA Faralli, MS Filla, YF Yang, YY Sun, K Johns, KE Keller, DM Peters Plos one 19 (2), e0298802, 2024 | | 2024 |
Profiling IOP-responsive genes in anterior and posterior ocular tissues in the rat CEI glaucoma model DC Lozano, YF Yang, WO Cepurna, BF Smoody, E Ing, JC Morrison, ... bioRxiv, 2024.02. 11.579818, 2024 | | 2024 |
Characterization of extracellular matrix deposited by segmental trabecular meshwork cells VK Raghunathan, A Nartey, K Dhamodaran, H Baidouri, JA Staverosky, ... Experimental Eye Research 234, 109605, 2023 | 3 | 2023 |
Glaucomatous trabecular meshwork cells induce Schlemm’s canal cell pathobiology in a biomimetic 3D ECM hydrogel co-culture model A Singh, S Patel, A Rajasekaran, AN Strat, KM Perkumas, WD Stamer, ... Investigative Ophthalmology & Visual Science 64 (8), 5077-5077, 2023 | 1 | 2023 |
Influence of hyaluronan depletion on CD44 and tunneling nanotubes in trabecular meshwork cells KE Keller, Y Yang, YYI Sun Investigative Ophthalmology & Visual Science 64 (8), 3448-3448, 2023 | | 2023 |
A method describing the microdissection of trabecular meshwork tissue from Brown Norway rat eyes E Ing, DC Lozano, WO Cepurna, F Chan, YF Yang, JC Morrison, ... Experimental eye research 228, 109367, 2023 | 2 | 2023 |
αvβ3 Integrin Expression in the Human Trabecular Meshwork/Schlemm’s Canal Pathway (TM/SC) is Age Dependent and Segmental JA Faralli, M Filla, H Khan, KE Keller, DM Peters Investigative Ophthalmology & Visual Science 63 (7), 3302–A0402-3302–A0402, 2022 | | 2022 |
Effects of biomechanical cues on filopodia, tunneling nanotubes, and myosin-X in trabecular meshwork cells KE Keller, YY Sun, YF Yang Investigative Ophthalmology & Visual Science 63 (7), 3300–A0400-3300–A0400, 2022 | | 2022 |
Isolation of trabecular meshwork (TM) RNA and analysis of gene expression following serial bevacizumab injections in rat eyes. E Ing, W Cepurna, DC Lozano, V O'Callahan, YF Yang, F Chan, KE Keller, ... Investigative Ophthalmology & Visual Science 63 (7), 2703–A0067-2703–A0067, 2022 | | 2022 |
The effects of mechanical stretch on integrins and filopodial-associated proteins in normal and glaucomatous trabecular meshwork cells YF Yang, YY Sun, DM Peters, KE Keller Frontiers in Cell and Developmental Biology 10, 886706, 2022 | 6 | 2022 |
Pathogenesis of glaucoma: Extracellular matrix dysfunction in the trabecular meshwork‐A review KE Keller, DM Peters Clinical & experimental ophthalmology 50 (2), 163-182, 2022 | 46 | 2022 |