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Hugo Snippert
Hugo Snippert
University Medical Center Utrecht, The Netherlands
Verified email at umcutrecht.nl - Homepage
Title
Cited by
Year
Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer
H Kayhanian, W Cross, SEM van der Horst, P Barmpoutis, E Lakatos, ...
Nature Genetics, 1-14, 2024
2024
DNA damage induces p53-independent apoptosis through ribosome stalling
NJ Boon, RA Oliveira, PR Körner, A Kochavi, S Mertens, Y Malka, ...
Science 384 (6697), 785-792, 2024
52024
Abstract LB301: BRAFV600E drives WNT signalling in colorectal cancer via aberrant DNA methylation
LE Bouazzaoui, JM Bugter, E Küçükköse, A Verheem, JB Post, ...
Cancer Research 84 (7_Supplement), LB301-LB301, 2024
2024
Meta-analysis of efficacy and safety in early-phase clinical trials for refractory colorectal cancer
MA Huismans, LP Smabers, NN van Nieuwenhuijzen, MC Minnema, ...
Cancer Research 84 (6_Supplement), 2386-2386, 2024
2024
Response to systemic therapies in patient-derived cell lines from primary and recurrent adult granulosa cell tumors
G Brink, N Hami, S Mertens, W Hofhuis, J Piek, C de Kroon, C Lok, ...
Cancer Research 84 (6_Supplement), 942-942, 2024
2024
Drug combinations for use in the treatment of RAS-mutant cancer
HJG Snippert, AEE Mertens, CSL Verissimo, JL Bos
US Patent 11,723,891, 2023
12023
Co-cultures of colon cancer cells and cancer-associated fibroblasts recapitulate the aggressive features of mesenchymal-like colon cancer
E Strating, MP Verhagen, E Wensink, E Dünnebach, L Wijler, I Aranguren, ...
Frontiers in Immunology 14, 1053920, 2023
152023
Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer
S Mertens, MA Huismans, CS Verissimo, B Ponsioen, R Overmeer, ...
Cell Reports 42 (4), 2023
222023
Multi-range ERK responses shape the proliferative trajectory of single cells following oncogene induction
JY Chen, C Hug, J Reyes, C Tian, L Gerosa, F Fröhlich, B Ponsioen, ...
Cell reports 42 (3), 2023
112023
Mechanical regulation of cell fate transitions underlying colorectal cancer metastasis formation
MC van der Net, MJ Vliem, LJS Kemp, C Perez-Gonzalez, EA Strating, ...
BioRxiv, 2023.09. 17.557771, 2023
12023
Zoltan Janos Vereb, University of Szeged, Hungary
ELS Fong, T Pankotai, O Kranenburg, E Strating, MP Verhagen, ...
2023
RNF43 mutations facilitate mucinous colorectal cancer metastasis via formation of a tumour-intrinsic niche
JM Bugter, L El Bouazzaoui, E Küçükköse, Y Hong, J Sprangers, ...
bioRxiv, 2022.12. 22.521159, 2022
22022
Multi range ERK responses shape the proliferative trajectory of single cells following oncogene induced senescence
JY Chen, C Hug, J Reyes, C Tian, L Gerosa, F Fröhlich, B Ponsioen, ...
bioRxiv, 2022.10. 06.511142, 2022
12022
Retrograde movements determine effective stem cell numbers in the intestine
M Azkanaz, B Corominas-Murtra, SIJ Ellenbroek, L Bruens, AT Webb, ...
Nature 607 (7919), 548-554, 2022
442022
Liver colonization by colorectal cancer metastases requires YAP-controlled plasticity at the micrometastatic stage
MC Heinz, NA Peters, KC Oost, RGH Lindeboom, L van Voorthuijsen, ...
Cancer research 82 (10), 1953-1968, 2022
412022
Efficient and error-free fluorescent gene tagging in human organoids without double-strand DNA cleavage
Y Bollen, JH Hageman, P van Leenen, LLM Derks, B Ponsioen, ...
PLoS Biology 20 (1), e3001527, 2022
132022
Reconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patterns
Y Bollen, E Stelloo, P van Leenen, M van den Bos, B Ponsioen, B Lu, ...
Nature genetics 53 (8), 1187-1195, 2021
452021
Chromosomal copy number heterogeneity predicts survival rates across cancers
E van Dijk, T Van Den Bosch, KJ Lenos, K El Makrini, LE Nijman, ...
Nature communications 12 (1), 3188, 2021
582021
Quantifying single-cell ERK dynamics in colorectal cancer organoids reveals EGFR as an amplifier of oncogenic MAPK pathway signalling
B Ponsioen, JB Post, JR Buissant des Amorie, D Laskaris, RL van Ineveld, ...
Nature cell biology 23 (4), 377-390, 2021
892021
Introducing the stem cell ASCL2 reporter STAR into intestinal organoids
MC Heinz, KC Oost, HJG Snippert
STAR protocols 1 (3), 100126, 2020
82020
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Articles 1–20