Exploiting a subtype-specific mitochondrial vulnerability for successful treatment of colorectal peritoneal metastases S Bootsma, MPG Dings, J Kesselaar, RF Helderman, K van Megesen, ... Cell Reports Medicine 5 (5), 2024 | | 2024 |
The pluripotency factor NANOG contributes to mesenchymal plasticity and is predictive for outcome in esophageal adenocarcinoma AP van der Zalm, MPG Dings, P Manoukian, H Boersma, R Janssen, ... Communications Medicine 4 (1), 89, 2024 | | 2024 |
Iron‐responsive element of divalent metal transporter 1 (Dmt1) controls Notch‐mediated cell fates J Hounjet, AJ Groot, JP Piepers, O Kranenburg, DA Zwijnenburg, ... The FEBS journal 290 (24), 5811-5834, 2023 | 1 | 2023 |
PD-12 Transcriptome-based classification to predict FOLFIRINOX response in a real-world metastatic pancreatic cancer cohort M Lansbergen, M Dings, P Manoukian, G Hooijer, AF Sarasqueta, ... Annals of Oncology 34, S5, 2023 | | 2023 |
ITCC-P4: Genomic profiling and analyses of pediatric patient tumor and patient-derived xenograft (PDX) models for high throughput in vivo testing A Gopisetty, A Federico, D Surdez, Y Iddir, S Zaidi, A Saint-Charles, ... Cancer Research 83 (7_Supplement), 234-234, 2023 | 1 | 2023 |
The ITCC-P4 sustainable platform of fully characterized PDXs supports the preclinical proof-of-concept drug testing of high-risk pediatric tumor models A Federico, A Gopisetty, D Surdez, Y Iddir, A Saint-Charles, J Wierzbinska, ... Cancer Research 83 (7_Supplement), 3571-3571, 2023 | 1 | 2023 |
Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulation MF Orth, D Surdez, T Faehling, AC Ehlers, A Marchetto, S Grossetête, ... Cell reports 41 (10), 2022 | 29 | 2022 |
Responses to systemic treatment in molecular subtypes of metastatic pancreatic cancer M Lansbergen, M Dings, C Waasdorp, G Hooijer, J Verheij, ... Pancreatology 22, e45, 2022 | | 2022 |
Estrogen-related receptor alpha drives mitochondrial biogenesis and resistance to neoadjuvant chemoradiation in esophageal cancer MPG Dings, AP van der Zalm, S Bootsma, TFJ van Maanen, C Waasdorp, ... Cell Reports Medicine 3 (11), 2022 | 22 | 2022 |
Modulation of macrophage inflammatory function through selective inhibition of the epigenetic reader protein SP140 M Ghiboub, J Koster, PD Craggs, AYF Li Yim, A Shillings, S Hutchinson, ... BMC biology 20 (1), 182, 2022 | 14 | 2022 |
A Common Genomic Denominator for Neuroblastoma and Differentiated Thyroid Carcinoma? A Case Series in Children SC Clement, J Koster, RP Kuiper, GAM Tytgat, ME Ebus, L Schild, ... Clinical oncology (Royal College of Radiologists (Great Britain)) 34 (7 …, 2022 | | 2022 |
Stemness factors nanog and oct4 contribute to epithelial-to-mesenchymal transition and are predictive for outcome in esophageal adenocarcinoma AP van der Zalm, MP Dings, R Janssen, P Bailey, J Koster, D Zwijnenburg, ... Cancer Research 82 (12_Supplement), 2616-2616, 2022 | | 2022 |
INSP-15. ITCC-P4: A sustainable platform of molecularly well-characterized PDX models of pediatric cancers for high throughputin vivo testing M Kool, A Federico, D Surdez, A Gopisetty, E Saberi-Ansari, ... Neuro-Oncology 24 (Supplement_1), i189-i189, 2022 | 1 | 2022 |
Mesenchymal-type neuroblastoma cells escape ALK inhibitors EM Westerhout, M Hamdi, P Stroeken, NE Nowakowska, A Lakeman, ... Cancer research 82 (3), 484-496, 2022 | 29 | 2022 |
Defects in 8-oxo-guanine repair pathway cause high frequency of C> A substitutions in neuroblastoma ML van den Boogaard, R Oka, A Hakkert, L Schild, ME Ebus, ... Proceedings of the National Academy of Sciences 118 (36), e2007898118, 2021 | 19 | 2021 |
An immature subset of neuroblastoma cells synthesizes retinoic acid and depends on this metabolite T van Groningen, CU Niklasson, A Chan, N Akogul, EM Westerhout, ... bioRxiv, 2021.05. 18.444639, 2021 | 5 | 2021 |
Specific and sensitive detection of neuroblastoma mRNA markers by multiplex RT-qPCR LMJ van Zogchel, L Zappeij-Kannegieter, A Javadi, M Lugtigheid, ... Cancers 13 (1), 150, 2021 | 16 | 2021 |
The molecular landscape of ETMR at diagnosis and relapse S Lambo, SN Gröbner, T Rausch, SM Waszak, C Schmidt, A Gorthi, ... Nature 576 (7786), 274-280, 2019 | 121 | 2019 |
Plasticity of transcriptional and epigenetic cellular states in neuroblastoma is driven by core lineage transcription factors J Nes, T Groningen, L Valentijn, D Zwijnenburg, EM Westerhout, M Hamdi, ... Cancer Research 79 (13_Supplement), 3662-3662, 2019 | | 2019 |
R2: Genomics analysis and visualization platform J Koster, R Volckmann, D Zwijnenburg, P Molenaar, R Versteeg Cancer Research 79 (13_Supplement), 2490-2490, 2019 | 45 | 2019 |