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Marek Liyanage
Marek Liyanage
Director, High Throughput Screening
Verified email at pliantrx.com
Title
Cited by
Year
Synthesis and structure-activity relationship of imidazoquinolone based inhibitors of glycogen synthase kinase 3 beta
B Li, Q Li, E Okerberg, T Nomanbhoy, O Cociorva, K Nakamura, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 247, 2014
2014
Hit-to-lead optimization and kinase selectivity of imidazo [1, 2-a] quinoxalin-4-amine derived JNK1 inhibitors
B Li, OM Cociorva, T Nomanbhoy, H Weissig, Q Li, K Nakamura, ...
Bioorganic & medicinal chemistry letters 23 (18), 5217-5222, 2013
312013
6-Position optimization of tricyclic 4-quinolone-based inhibitors of glycogen synthase kinase-3 beta: Discovery of nitrile derivatives with picomolar potency
OM Cociorva, B Li, T Nomanbhoy, Q Li, K Nakamura, M Nomura, K Okada, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 243, 2012
2012
6-Position optimization of tricyclic 4-quinolone-based inhibitors of glycogen synthase kinase-3β: Discovery of nitrile derivatives with picomolar potency
B Li, OM Cociorva, T Nomanbhoy, Q Li, K Nakamura, M Nomura, K Okada, ...
Bioorganic & medicinal chemistry letters 22 (2), 1005-1008, 2012
82012
Synthesis and structure–activity relationship of 4-quinolone-3-carboxylic acid based inhibitors of glycogen synthase kinase-3β
OM Cociorva, B Li, T Nomanbhoy, Q Li, A Nakamura, K Nakamura, ...
Bioorganic & medicinal chemistry letters 21 (19), 5948-5951, 2011
292011
Acyl-nucleotide probes and methods of their synthesis and use in proteomic analysis
DA Campbell, M Liyanage, AK Szardenings, M Wu
US Patent 7,365,178, 2008
122008
Functional interrogation of the kinome using nucleotide acyl phosphates
MP Patricelli, AK Szardenings, M Liyanage, TK Nomanbhoy, M Wu, ...
Biochemistry 46 (2), 350-358, 2007
4692007
Abnormal rearrangement within the α/δ T-cell receptor locus in lymphomas from Atm-deficient mice
M Liyanage, Z Weaver, C Barlow, A Coleman, DG Pankratz, S Anderson, ...
Blood, The Journal of the American Society of Hematology 96 (5), 1940-1946, 2000
1712000
Nucleoli in a pronuclei-stage mouse embryo are represented by major satellite DNA of interconnecting chromosomes
D Dozortsev, A Coleman, P Nagy, MP Diamond, A Ermilov, U Weier, ...
Fertility and sterility 73 (2), 366-371, 2000
312000
Human DNA sequence polymorphisms: New opportunities for drug discovery and customized patient care
MS Liyanage, KG Xanthopoulos
Drug development research 49 (1), 46-53, 2000
12000
A recurring pattern of chromosomal aberrations in mammary gland tumors of MMTV‐cmyc transgenic mice
ZA Weaver, SJ McCormack, M Liyanage, S du Manoir, A Coleman, ...
Genes, Chromosomes and Cancer 25 (3), 251-260, 1999
1041999
Developing targets for drug discovery using genome-wide gene trapping and ultra-sensitive beta-lactamase reporters.
M Liyanage, EM Zamiara, B Mandurrago, M Riley, P Sanders, ...
Proceedings of the Western Pharmacology Society 42, 123-126, 1999
1999
Symposia and Plenary Presentations-Developing Targets for Drug Discovery Using Genome-Wide Gene Trapping and Ultra-Sensitive b-Lactamase Reporters
M Liyanage, E Grazzini, B Mandurrago, M Riley, P Sanders, HL Welchlin, ...
Proceedings of the Western Pharmacology Society 42, 123-126, 1999
1999
Amplification of Ki-ras and elevation of MAP kinase activity during mammary tumor progression in C3 (1)/SV40 Tag transgenic mice
ML Liu, FC Von Lintig, M Liyanage, MA Shibata, CL Jorcyk, T Ried, ...
Oncogene 17 (18), 2403-2411, 1998
511998
Atm deficiency results in severe meiotic disruption as early as leptonema of prophase I
C Barlow, M Liyanage, PB Moens, M Tarsounas, K Nagashima, K Brown, ...
Development 125 (20), 4007-4017, 1998
3451998
Myc/p53 interactions in transgenic mouse mammary development, tumorigenesis and chromosomal instability
SJ McCormack, Z Weaver, S Deming, G Natarajan, J Torri, MD Johnson, ...
Oncogene 16 (21), 2755-2766, 1998
1121998
Chromosomal Arrangement During the Pronuclei Stage in Mouse Zygote
D Dozortsev, A Ermilov, IB Chang, A Coleman, M Liyanage, T Ried
FERTILITY AND STERILITY-INTERNATIONAL EDITION- 70, O-018, 1998
1998
Partial rescue of the prophase I defects of Atm-deficient mice by p53 and p21 null alleles
C Barlow, M Liyanage, PB Moens, CX Deng, T Ried, A Wynshaw-Boris
Nature genetics 17 (4), 462-466, 1997
1461997
Molecular mechanisms for infertility and cancer in ataxia telangiectasia
M Liyanage, C Barlow, PB Moens, D Wangsa, CX Deng, A WynshawBoris, ...
MOLECULAR BIOLOGY OF THE CELL 8, 2050-2050, 1997
1997
Tumor cytogenetics revisited: comparative genomic hybridization and spectral karyotyping
T Ried, M Liyanage, S du Manoir, K Heselmeyer, G Auer, M Macville, ...
Journal of molecular medicine 75, 801-814, 1997
1351997
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