Deep Learning-Based Identification of Intraocular Pressure-Associated Genes Influencing Trabecular Meshwork Cell Morphology CJ Greatbatch, Q Lu, S Hung, SN Tran, K Wing, H Liang, X Han, T Zhou, ... Ophthalmology Science 4 (4), 100504, 2024 | | 2024 |
A semi-automated pipeline for quantifying drusen-like deposits in human induced pluripotent stem cell-derived retinal pigment epithelium cells J Hall, M Daniszewski, S Cheung, K Shobhana, H Kumar, HH Liang, ... SLAS technology 29 (3), 100106, 2024 | | 2024 |
High throughput functional profiling of genes at intraocular pressure loci reveals distinct networks for glaucoma CJ Greatbatch, Q Lu, S Hung, AJ Barnett, K Wing, H Liang, X Han, T Zhou, ... Human Molecular Genetics 33 (9), 739-751, 2024 | 1 | 2024 |
Transcriptomic and proteomic retinal pigment epithelium signatures of age-related macular degeneration A Senabouth, M Daniszewski, GE Lidgerwood, HH Liang, D Hernández, ... Nature Communications 13 (1), 4233, 2022 | 39 | 2022 |
Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma M Daniszewski, A Senabouth, HH Liang, X Han, GE Lidgerwood, ... Cell Genomics 2 (6), 2022 | 12 | 2022 |
Culture variabilities of human iPSC-derived cerebral organoids are a major issue for the modelling of phenotypes observed in Alzheimer’s disease D Hernández, LA Rooney, M Daniszewski, L Gulluyan, HH Liang, ... Stem Cell Reviews and Reports, 1-14, 2022 | 74 | 2022 |
Association of smoking, alcohol consumption, blood pressure, body mass index, and glycemic risk factors with age-related macular degeneration: a Mendelian randomization study V Kuan, A Warwick, A Hingorani, A Tufail, V Cipriani, S Burgess, R Sofat, ... JAMA ophthalmology 139 (12), 1299-1306, 2021 | 44 | 2021 |
Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells D Neavin, Q Nguyen, MS Daniszewski, HH Liang, HS Chiu, YK Wee, ... Genome biology 22, 1-19, 2021 | 76 | 2021 |
Automated system for maintenance and differentiation of pluripotent stem cells A Pebay, A Hewitt, D Crombie, H Liang, R Wong, M Daniszewski, ... US Patent 11,149,245, 2021 | 1 | 2021 |
Investigating the role of APOE: limitations of human pluripotent stem cell-derived cerebral organoids D Hernández, LA Rooney, M Daniszewski, L Gulluyan, HH Liang, ... bioRxiv, 2020.11. 30.405654, 2020 | | 2020 |
OXPHOS bioenergetic compensation does not explain disease penetrance in Leber hereditary optic neuropathy MIGL Sanchez, NJ Van Bergen, LS Kearns, M Ziemann, H Liang, ... Mitochondrion 54, 113-121, 2020 | 9 | 2020 |
High-throughput CRISPR-based morphological profiling of IOP-associated genes in primary trabecular meshwork cells P Lu, S Hung, C Greatbatch, H Liang, R Liu, D Mackey, A Cook, ... Clinical and Experimental Ophthalmology 47, 121-122, 2019 | | 2019 |
CRISPR/Cas-mediated base editing of the AMD high-risk Y402H complement factor H variant AW Hewitt, P Tran, MKNM Khalid, A Pébay, AL Cook, H Liang, R Wong, ... Investigative Ophthalmology & Visual Science 60 (9), 4947-4947, 2019 | | 2019 |
Screening of CRISPR/Cas base editors to target the AMD high-risk Y402H complement factor H variant MTN Tran, MKNM Khalid, A Pébay, AL Cook, HH Liang, RCB Wong, ... Molecular Vision 25, 174, 2019 | 12 | 2019 |
A need for better understanding is the major determinant for public perceptions of human gene editing T McCaughey, DM Budden, PG Sanfilippo, GEC Gooden, L Fan, ... Human gene therapy 30 (1), 36-43, 2019 | 37 | 2019 |
Single-cell profiling identifies key pathways expressed by iPSCs cultured in different commercial media M Daniszewski, Q Nguyen, HS Chy, V Singh, DE Crombie, T Kulkarni, ... Iscience 7, 30-39, 2018 | 21 | 2018 |
Automated cell culture systems and their applications to human pluripotent stem cell studies M Daniszewski, DE Crombie, R Henderson, HH Liang, RCB Wong, ... SLAS TECHNOLOGY: Translating Life Sciences Innovation 23 (4), 315-325, 2018 | 53 | 2018 |
Role of lysophosphatidic acid in the retinal pigment epithelium and photoreceptors GE Lidgerwood, AJ Morris, A Conquest, M Daniszewski, LA Rooney, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2018 | 26 | 2018 |
Development of a modular automated system for maintenance and differentiation of adherent human pluripotent stem cells DE Crombie, M Daniszewski, HH Liang, T Kulkarni, F Li, GE Lidgerwood, ... Slas Discovery: Advancing Life Sciences R&D 22 (8), 1016-1025, 2017 | 39 | 2017 |
[P4–399]: MODELLING ALZHEIMER's DISEASE USING HUMAN CORTICAL CEREBRAL ORGANOIDS D Hernández, DE Crombie, HH Liang, L Kearns, SW Ng, E de Smit, ... Alzheimer's & Dementia 13 (7S_Part_31), P1482-P1483, 2017 | | 2017 |