Identifying human pre-mRNA cleavage and polyadenylation factors by genome-wide CRISPR screens using a dual fluorescence readthrough reporter Z Ni, N Ahmed, S Nabeel-Shah, X Guo, S Pu, J Song, E Marcon, GL Burke, ... Nucleic Acids Research 52 (8), 4483-4501, 2024 | | 2024 |
Recruitment of the m6A/Am demethylase FTO to target RNAs by the telomeric zinc finger protein ZBTB48 S Nabeel-Shah, S Pu, GL Burke, N Ahmed, U Braunschweig, ... bioRxiv, 2024.01. 15.575768, 2024 | 2 | 2024 |
Changes in SUMO-modified proteins in Epstein-Barr virus infection identifies reciprocal regulation of TRIM24/28/33 complexes and the lytic switch BZLF1 CF De La Cruz-Herrera, MH Tatham, UZ Siddiqi, K Shire, E Marcon, ... PLoS Pathogens 19 (7), e1011477, 2023 | 5 | 2023 |
N-6-methyladenosine (m6A) Promotes the Nuclear Retention of mRNAs with Intact 5’ Splice Site Motifs ES Lee, HW Smith, SSJ Ihn, L Scalize de Olivera, YE Wang, RY Jomphe, ... bioRxiv, 2023.06. 20.545713, 2023 | 3 | 2023 |
Revised iCLIP-seq Protocol for Profiling RNA–protein Interaction Sites at Individual Nucleotide Resolution in Living Cells S Nabeel-Shah, JF Greenblatt Bio-protocol 13 (11), 2023 | 3 | 2023 |
Multilevel interrogation of H3. 3 reveals a primordial role in transcription regulation S Nabeel-Shah, J Garg, K Ashraf, R Jeyapala, H Lee, A Petrova, JD Burns, ... Epigenetics & Chromatin 16 (1), 10, 2023 | 2 | 2023 |
RNA-binding proteins that lack canonical RNA-binding domains are rarely sequence-specific D Ray, KU Laverty, A Jolma, K Nie, R Samson, SE Pour, CL Tam, ... Scientific Reports 13 (1), 5238, 2023 | 19 | 2023 |
A central chaperone-like role for 14-3-3 proteins in human cells D Segal, S Maier, GJ Mastromarco, WW Qian, S Nabeel-Shah, H Lee, ... Molecular cell 83 (6), 974-993. e15, 2023 | 22 | 2023 |
Survival-based CRISPR genetic screens across a panel of permissive cell lines identify common and cell-specific SARS-CoV-2 host factors K Chan, AG Farias, H Lee, F Guvenc, P Mero, KR Brown, H Ward, ... Heliyon 9 (1), 2023 | 9 | 2023 |
A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II Y Liu, A Iqbal, W Li, Z Ni, Y Wang, J Ramprasad, KJ Abraham, M Zhang, ... Nature communications 13 (1), 5453, 2022 | 14 | 2022 |
Regulation of alternative polyadenylation by the C2H2-zinc-finger protein Sp1 J Song, S Nabeel-Shah, S Pu, H Lee, U Braunschweig, Z Ni, N Ahmed, ... Molecular Cell 82 (17), 3135-3150. e9, 2022 | 20 | 2022 |
The amino acid sensor GCN2 suppresses terminal oligopyrimidine (TOP) mRNA translation via La-related protein 1 (LARP1) Z Farooq, F Kusuma, P Burke, CR Dufour, D Lee, N Tabatabaei, P Toboz, ... Journal of Biological Chemistry 298 (9), 2022 | 7 | 2022 |
Systematic exploration of dynamic splicing networks reveals conserved multistage regulators of neurogenesis H Han, AJ Best, U Braunschweig, N Mikolajewicz, JD Li, J Roth, ... Molecular cell 82 (16), 2982-2999. e14, 2022 | 16 | 2022 |
SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response S Nabeel-Shah, H Lee, N Ahmed, GL Burke, S Farhangmehr, K Ashraf, ... IScience 25 (1), 2022 | 65 | 2022 |
Epstein-Barr Virus BGLF2 commandeers RISC to interfere with cellular miRNA function AM Campbell, F Carlos, E Marcon, J Greenblatt, L Frappier PLoS Pathogens 18 (1), e1010235, 2022 | 10 | 2022 |
A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization D Dilworth, RP Hanley, R Ferreira de Freitas, A Allali-Hassani, M Zhou, ... Nature chemical biology 18 (1), 56-63, 2022 | 48 | 2022 |
KRAB Zinc Finger protein Znf684 interacts with Nxf1 to regulate mRNA export A Nitoiu, S Nabeel-Shah, S Farhangmehr, S Pu, U Braunschweig, ... bioRxiv, 2021.09. 29.462476, 2021 | 1 | 2021 |
Characterization of a cancer-associated Epstein-Barr virus EBNA1 variant reveals a novel interaction with PLOD1 and PLOD3 K Shire, E Marcon, J Greenblatt, L Frappier Virology 562, 103-109, 2021 | 9 | 2021 |
Systematic genome-scale identification of host factors for SARS-CoV-2 infection across models yields a core single gene dependency; ACE2 K Chan, AG Farias, H Lee, F Guvenc, P Mero, K Aulakh, KR Brown, ... BioRxiv, 2021.06. 28.450244, 2021 | 2 | 2021 |
Functional characterization of RebL1 highlights the evolutionary conservation of oncogenic activities of the RBBP4/7 orthologue in Tetrahymena thermophila S Nabeel-Shah, J Garg, A Saettone, K Ashraf, H Lee, S Wahab, N Ahmed, ... Nucleic Acids Research 49 (11), 6196-6212, 2021 | 17 | 2021 |