Systems and Methods for Modulating CRISPR Activity R Kelso, J Carlson-Stevermer, S Joshi, T Maures, A Kadina, JA Walker US Patent App. 18/532,892, 2024 | | 2024 |
Gene correction of pompe disease and other autosomal recessive disorders via rna-guided nucleases K Saha, JM Carlson-Stevermer, LK Kohlenberg US Patent App. 18/348,573, 2024 | | 2024 |
Systems and methods for modulating CRISPR activity R Kelso, J Carlson-Stevermer, S Joshi, T Maures, A Kadina, IIJA Walker US Patent 11,884,918, 2024 | | 2024 |
Long term rescue of Alzheimer deficits in vivo by one-time gene-editing of App C-terminus. B Aulston, K Gimse, HO Bazick, EA Kramar, DP Pizzo, LA Parra-Rivas, ... bioRxiv, 2024.06. 08.598099, 2024 | | 2024 |
Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets KM Haas, MJ McGregor, M Bouhaddou, BJ Polacco, EY Kim, TT Nguyen, ... Nature communications 14 (1), 6030, 2023 | 10 | 2023 |
Gene correction of Pompe disease and other autosomal recessive disorders via RNA-guided nucleases K Saha, JM Carlson-Stevermer, LK Kohlenberg US Patent 11,739,320, 2023 | | 2023 |
Viral E protein neutralizes BET protein-mediated post-entry antagonism of SARS-CoV-2 IP Chen, JE Longbotham, S McMahon, RK Suryawanshi, MM Khalid, ... Cell reports 40 (3), 2022 | 20 | 2022 |
Identification of DAXX as a restriction factor of SARS-CoV-2 through a CRISPR/Cas9 screen A Mac Kain, G Maarifi, SM Aicher, N Arhel, A Baidaliuk, S Munier, ... Nature Communications 13 (1), 2442, 2022 | 31 | 2022 |
Stabilized CRISPR Complexes T Maures, J Carlson-Stevermer, S Joshi, R Kelso, A Kadina, IIJA Walker US Patent App. 17/384,417, 2022 | | 2022 |
BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2 AJ Samelson, QD Tran, R Robinot, L Carrau, VV Rezelj, AM Kain, M Chen, ... Nature cell biology 24 (1), 24-34, 2022 | 68* | 2022 |
Inhibitors of VPS34 and fatty-acid metabolism suppress SARS-CoV-2 replication CG Williams, AS Jureka, JA Silvas, AM Nicolini, SA Chvatal, ... Cell reports 36 (5), 2021 | 58 | 2021 |
Modified guide rnas, crispr-ribonucleotprotein complexes and methods of use JM Carlson-Stevermer, K Saha, AA Abdeen, LK Kohlenberg US Patent App. 17/121,187, 2021 | 1 | 2021 |
Design of Efficacious Somatic Cell Genome Editing Strategies for Recessive and Polygenic Diseases A Das, J Carlson-Stevermer, A Abdeen, D Fiflis, B Grindel, S Saxena, ... MOLECULAR THERAPY 29 (4), 204-205, 2021 | | 2021 |
Modified guide RNAs, CRISPR-ribonucleotprotein complexes and methods of use JM Carlson-Stevermer, K Saha, AA Abdeen, LK Kohlenberg US Patent 10,907,150, 2021 | | 2021 |
Genetic screens identify host factors for SARS-CoV-2 and common cold coronaviruses R Wang, CR Simoneau, J Kulsuptrakul, M Bouhaddou, KA Travisano, ... Cell 184 (1), 106-119. e14, 2021 | 348 | 2021 |
BRD2 inhibition blocks SARS-CoV-2 infection in vitro by reducing transcription of the host cell receptor ACE2 AJ Samelson, QD Tran, R Robinot, L Carrau, VV Rezelj, A Mac Kain, ... | | 2021 |
Design of efficacious somatic cell genome editing strategies for recessive and polygenic diseases J Carlson-Stevermer, A Das, AA Abdeen, D Fiflis, BI Grindel, S Saxena, ... Nature communications 11 (1), 6277, 2020 | 11 | 2020 |
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ... Science 370 (6521), eabe9403, 2020 | 635 | 2020 |
CRISPRoff enables spatio-temporal control of CRISPR editing J Carlson-Stevermer, R Kelso, A Kadina, S Joshi, N Rossi, J Walker, ... Nature communications 11 (1), 5041, 2020 | 38 | 2020 |
Functional genomic screens identify human host factors for SARS-CoV-2 and common cold coronaviruses R Wang, CR Simoneau, J Kulsuptrakul, M Bouhaddou, K Travisano, ... BioRxiv, 2020 | 26 | 2020 |