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Isaac Pessah
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Year
The α4 Nicotinic Acetylcholine Receptor Is Necessary for the Initiation of Organophosphate-Induced Neuronal Hyperexcitability
PM Andrew, W Feng, JJ Calsbeek, SP Antrobus, GA Cherednychenko, ...
Toxics 12 (4), 263, 2024
2024
The Piezo channel is a mechano-sensitive complex component in the mammalian inner ear hair cell
JH Lee, MC Perez-Flores, S Park, HJ Kim, Y Chen, M Kang, J Kersigo, ...
Nature communications 15 (1), 526, 2024
32024
Ex vivo exposure to polybrominated diphenyl ether (PBDE) selectively affects the immune response in autistic children
ME Akintunde, Y Lin, P Krakowiak, IN Pessah, I Hertz-Picciotto, ...
Brain, Behavior, & Immunity-Health 34, 100697, 2023
2023
Putative malignant hyperthermia mutation CaV1. 1-R174W is insufficient to trigger a fulminant response to halothane or confer heat stress intolerance
W Feng, JR Lopez, S Antrobus, J Zheng, A Uryash, Y Dong, D Beqollari, ...
Journal of Biological Chemistry 299 (8), 2023
2023
The Piezo channel is central to the mechano-sensitive channel complex in the mammalian inner ear
JH Lee, MC Perez-Flores, S Park, HJ Kim, Y Chen, M Kang, J Kersigo, ...
Research Square, 2023
12023
Mitigation of epileptic seizures by combination therapy using benzodiazepines and neurosteroids
MA Rogawski, IN Pessah, CAO Zhengyu
US Patent App. 17/990,661, 2023
2023
Investigations into hydrogen sulfide-induced suppression of neuronal activity in vivo and calcium dysregulation in vitro
DS Kim, IN Pessah, CM Santana, BS Purnell, R Li, GF Buchanan, ...
Toxicological Sciences 192 (2), 247-264, 2023
82023
Ryanodine receptor-active non-dioxin-like polychlorinated biphenyls cause neurobehavioral deficits in larval zebrafish
B Yaghoobi, GW Miller, EB Holland, X Li, D Harvey, S Li, HJ Lehmler, ...
Frontiers in toxicology 4, 947795, 2022
72022
Rare coding variation provides insight into the genetic architecture and phenotypic context of autism
JM Fu, FK Satterstrom, M Peng, H Brand, RL Collins, S Dong, B Wamsley, ...
Nature genetics 54 (9), 1320-1331, 2022
2352022
Sunjay Sethi1†, Kimberly P. Keil Stietz1†‡, Anthony E. Valenzuela1, Carolyn R. Klocke1, Jill L. Silverman2, 3, Birgit Puschner1‡, Isaac N. Pessah1, 3 and Pamela J. Lein1, 3
B Puschner, S Sethi, KS KP, AE Valenzuela, CR Klocke, JL Silverman, ...
Brain abnormalities due to genetic alterations or developmental exposure to …, 2022
2022
The seizure‐inducing plastic explosive RDX inhibits the α1β2γ2 GABAA receptor
B Pressly, RD Lee, V Singh, IN Pessah, H Wulff
Annals of clinical and translational neurology 9 (5), 600-609, 2022
52022
Dehydropiandrosterone (DHEA) reduces core body temperature and protects against heat stress intolerance in RYR1-T4826IHSI malignant hyperthermia susceptible mice
S Antrobus, W Feng, IN Pessah
Biophysical Journal 121 (3), 504a, 2022
2022
Rare coding variation illuminates the allelic architecture, risk genes, cellular expression patterns, and phenotypic context of autism
JM Fu, FK Satterstrom, M Peng, H Brand, RL Collins, S Dong, L Klei, ...
MedRxiv, 2021.12. 20.21267194, 2021
342021
Developmental exposure to a human-relevant polychlorinated biphenyl mixture causes behavioral phenotypes that vary by sex and genotype in juvenile mice expressing human …
S Sethi, KP Keil Stietz, AE Valenzuela, CR Klocke, JL Silverman, ...
Frontiers in Neuroscience 15, 766826, 2021
232021
Sex and genotype modulate the dendritic effects of developmental exposure to a human-relevant polychlorinated biphenyls mixture in the juvenile mouse
KP Keil Stietz, S Sethi, CR Klocke, TE de Ruyter, MD Wilson, IN Pessah, ...
Frontiers in Neuroscience 15, 766802, 2021
162021
Marine and Anthropogenic Bromopyrroles Alter Cellular Ca2+ Dynamics of Murine Cortical Neuronal Networks by Targeting the Ryanodine Receptor and Sarco/Endoplasmic …
J Zheng, S Antrobus, W Feng, TN Purdy, BS Moore, IN Pessah
Environmental science & technology 55 (23), 16023-16033, 2021
22021
Surfactant cocamide monoethanolamide causes eye irritation by activating nociceptor TRPV1 channels
F Zhao, S Wang, Y Li, J Wang, Y Wang, C Zhang, Y Li, L Huang, Y Yu, ...
British journal of pharmacology 178 (17), 3448-3462, 2021
52021
Structure-activity relationship of neuroactive steroids, Midazolam, and Perampanel toward Mitigating tetramine-triggered activity in murine hippocampal neuronal networks
S Antrobus, B Pressly, AM Nik, H Wulff, IN Pessah
Toxicological Sciences 180 (2), 325-341, 2021
52021
Non-dioxin-like polychlorinated biphenyl neurotoxic equivalents found in environmental and human samples
EB Holland, IN Pessah
Regulatory Toxicology and Pharmacology 120, 104842, 2021
132021
Human cerebral cortex proteome of fragile X-associated tremor/ataxia syndrome
KN Holm, AW Herren, SL Taylor, JL Randol, K Kim, G Espinal, ...
Frontiers in Molecular Biosciences 7, 600840, 2021
132021
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