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Jan Dekker (rekkednaj@gmail.com)
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Year
Age-associated impairment of the mucus barrier function is associated with profound changes in microbiota and immunity
B Sovran, F Hugenholtz, M Elderman, AA Van Beek, K Graversen, ...
Scientific reports 9 (1), 1437, 2019
1812019
Lactose intolerance and regulation of small intestinal lactase activity
RK Montgomery, HA Büller, EΗΗΜ Rings, J Dekker, RJ Grand
Nutrition and gene expression, 23-53, 2018
52018
The effect of age on the intestinal mucus thickness, microbiota composition and immunity in relation to sex in mice
M Elderman, B Sovran, F Hugenholtz, K Graversen, M Huijskes, ...
PloS one 12 (9), e0184274, 2017
1422017
Homeostasis of the gut barrier and potential biomarkers
JM Wells, RJ Brummer, M Derrien, TT MacDonald, F Troost, PD Cani, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 312 (3 …, 2017
5692017
Aging-induced decline in mucus thickness in mice is associated with changes in microbiota composition and immunity and is sex dependent
M Elderman, B Sovran, F Hugenholtz, K Graversen, M Huijskes, ...
Wageningen University, 2017
2017
Identification of commensal species positively correlated with early stress responses to a compromised mucus barrier
B Sovran, P Lu, LMP Loonen, F Hugenholtz, C Belzer, EH Stolte, ...
Inflammatory bowel diseases 22 (4), 826-840, 2016
372016
Capsaicin-induced satiety is associated with gastrointestinal distress but not with the release of satiety hormones
M van Avesaat, FJ Troost, MS Westerterp-Plantenga, Z Helyes, ...
The American journal of clinical nutrition 103 (2), 305-313, 2016
712016
Aging induced decline in mucus integrity is associated with changes in microbiota composition and immunity, and is sex dependent
M Elderman, B Sovran, F Hugenholtz, K Graversen, M Huijskes, ...
Intestinal host-microbe interactions and sex, 99, 2016
2016
Gut microbiota facilitates dietary heme-induced epithelial hyperproliferation by opening the mucus barrier in colon
N Ijssennagger, C Belzer, GJ Hooiveld, J Dekker, SWC van Mil, M Müller, ...
Proceedings of the National Academy of Sciences 112 (32), 10038-10043, 2015
3922015
Visceral hypersensitivity in irritable bowel syndrome: evidence for involvement of serotonin metabolism–a preliminary study
D Keszthelyi, FJ Troost, DM Jonkers, HM Van Eijk, J Dekker, WA Buurman, ...
Neurogastroenterology & Motility 27 (8), 1127-1137, 2015
462015
IL-22-STAT3 pathway plays a key role in the maintenance of ileal homeostasis in mice lacking secreted mucus barrier
B Sovran, LMP Loonen, P Lu, F Hugenholtz, C Belzer, EH Stolte, ...
Inflammatory bowel diseases 21 (3), 531-542, 2015
672015
Microbiota facilitates dietary heme-induced epithelial hyperproliferation and hyperplasia by breaking the mucus barrier
N IJssennagger, C Belzer, G Hooiveld, J Dekker, M Müller, ...
Red meat and colon cancer, 107, 2015
2015
Homeostatic mechanisms prevent ileitis in mice with deficient MUC2 production
B Sovran, LMP Loonen, P Lu, E Kranenbarg, C Belzer, M Boekschoten, ...
Immunology 143, 23-23, 2014
2014
Ethanol impairs intestinal barrier function in humans through mitogen activated protein kinase signaling: a combined in vivo and in vitro approach
E Elamin, A Masclee, F Troost, HJ Pieters, D Keszthelyi, K Aleksa, ...
PloS one 9 (9), e107421, 2014
852014
Serotonergic reinforcement of intestinal barrier function is impaired in irritable bowel syndrome
D Keszthelyi, FJ Troost, DM Jonkers, HM van Eijk, PJ Lindsey, J Dekker, ...
Alimentary pharmacology & therapeutics 40 (4), 392-402, 2014
542014
Cytotoxicity and metabolic stress induced by acetaldehyde in human intestinal LS174T goblet-like cells
E Elamin, A Masclee, F Troost, J Dekker, D Jonkers
American Journal of Physiology-Gastrointestinal and Liver Physiology 307 (3 …, 2014
392014
REG3γ-deficient mice have altered mucus distribution and increased mucosal inflammatory responses to the microbiota and enteric pathogens in the ileum
LMP Loonen, EH Stolte, MTJ Jaklofsky, M Meijerink, J Dekker, ...
Mucosal immunology 7 (4), 939-947, 2014
1952014
Ethanol disrupts intestinal epithelial tight junction integrity through intracellular calcium-mediated Rho/ROCK activation
E Elamin, A Masclee, J Dekker, D Jonkers
American Journal of Physiology-Gastrointestinal and Liver Physiology 306 (8 …, 2014
822014
Transient inflammatory-like state and microbial dysbiosis are pivotal in establishment of mucosal homeostasis during colonisation of germ-free mice
S El Aidy, M Derrien, R Aardema, G Hooiveld, SE Richards, A Dane, ...
Beneficial Microbes 5 (1), 67-77, 2014
832014
Activation of the epithelial‐to‐mesenchymal transition factor snail mediates acetaldehyde‐induced intestinal epithelial barrier disruption
E Elamin, A Masclee, F Troost, J Dekker, D Jonkers
Alcoholism: Clinical and Experimental Research 38 (2), 344-353, 2014
372014
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