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| Downregulation of Hsp90 and the antimicrobial peptide Mtk suppresses poly (GR)-induced neurotoxicity in C9ORF72-ALS/FTD S Lee, YW Jun, GR Linares, B Butler, Y Yuva-Adyemir, J Moore, ... Neuron 111 (9), 1381-1390. e6, 2023 | 8 | 2023 |
| The exocyst complex in neurological disorders DO Halim, M Munson, FB Gao Human Genetics, 1-8, 2023 | 2 | 2023 |
| Non-muscle MYH10/myosin IIB recruits ESCRT-III to participate in autophagosome closure to maintain neuronal homeostasis YW Jun, S Lee, BK Ban, JA Lee, FB Gao Autophagy, 1-17, 2023 | 2 | 2023 |
| PIKFYVE inhibition mitigates disease in models of diverse forms of ALS ST Hung, GR Linares, WH Chang, Y Eoh, G Krishnan, S Mendonca, ... Cell 186 (4), 786-802. e28, 2023 | 36 | 2023 |
| Dorsomedial prefrontal hypoexcitability underlies lost empathy in frontotemporal dementia HL Phillips, H Dai, SY Choi, K Jansen-West, AS Zajicek, L Daly, ... Neuron, 2023 | 8 | 2023 |
| The enhanced association between mutant CHMP2B and spastin is a novel pathological link between frontotemporal dementia and hereditary spastic paraplegias Y Chen, G Krishnan, S Parsi, M Pons, V Nikolaki, L Cao, Z Xu, FB Gao Acta Neuropathologica Communications 10 (1), 169, 2022 | 1 | 2022 |
| CRISPR/Cas9-mediated excision of ALS/FTD-causing hexanucleotide repeat expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro KE Meijboom, A Abdallah, NP Fordham, H Nagase, T Rodriguez, C Kraus, ... Nature communications 13 (1), 6286, 2022 | 41 | 2022 |
| Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM AB Loveland, E Svidritskiy, D Susorov, S Lee, A Park, S Zvornicanin, ... Nature Communications 13 (1), 2776, 2022 | 45 | 2022 |
| Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD G Krishnan, D Raitcheva, D Bartlett, M Prudencio, DM McKenna-Yasek, ... Nature communications 13 (1), 2799, 2022 | 31 | 2022 |
| Excessive release of inorganic polyphosphate by ALS/FTD astrocytes causes non-cell-autonomous toxicity to motoneurons C Arredondo, C Cefaliello, A Dyrda, N Jury, P Martinez, I Díaz, A Amaro, ... Neuron 110 (10), 1656-1670. e12, 2022 | 47 | 2022 |
| RNA targets of TDP-43: Which one is more important in neurodegeneration? D Halim, FB Gao Translational Neurodegeneration 11 (1), 12, 2022 | 2 | 2022 |
| Ribosome profiling reveals novel regulation of C9ORF72 GGGGCC repeat-containing RNA translation HM van‘t Spijker, EE Stackpole, S Almeida, O Katsara, B Liu, K Shen, ... Rna 28 (2), 123-138, 2022 | 21 | 2022 |
| Translation of dipeptide repeat proteins in C9ORF72-ALS/FTD through unique and redundant AUG initiation codons Y Sonobe, S Lee, G Krishnan, Y Gu, DY Kwon, FB Gao, R Roos, ... bioRxiv, 2022.08. 06.503063, 2022 | 3 | 2022 |
| A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation Y Sonobe, J Aburas, G Krishnan, AC Fleming, G Ghadge, P Islam, ... Nature communications 12 (1), 6025, 2021 | 30 | 2021 |
| Translation of the poly (GR) frame in C9ORF72-ALS/FTD is regulated by cis-elements involved in alternative splicing A Lampasona, S Almeida, FB Gao Neurobiology of aging 105, 327-332, 2021 | 9 | 2021 |
| Compositions and methods for the treatment of expanded repeat-associated disorders JD Richter, FB Gao US Patent App. 17/130,908, 2021 | | 2021 |
| TBK1 haploinsufficiency in ALS and FTD compromises membrane trafficking Y Lu, S Almeida, FB Gao Acta neuropathologica 142 (1), 217-221, 2021 | 6 | 2021 |
| p53 is a central regulator driving neurodegeneration caused by C9orf72 poly (PR) M Maor-Nof, Z Shipony, R Lopez-Gonzalez, L Nakayama, YJ Zhang, ... Cell 184 (3), 689-708. e20, 2021 | 117 | 2021 |
| Compositions and methods for the treatment of expanded repeat-associated disorders JD Richter, FB Gao US Patent 10,905,707, 2021 | 10 | 2021 |