An integrated structural model of the DNA damage-responsive H3K4me3 binding WDR76: SPIN1 complex with the nucleosome X Liu, Y Zhang, Z Wen, Y Hao, CAS Banks, J Cesare, S Bhattacharya, ... Proceedings of the National Academy of Sciences 121 (33), e2318601121, 2024 | | 2024 |
Structure of the Hir histone chaperone complex HJ Kim, MR Szurgot, T van Eeuwen, MD Ricketts, P Basnet, AL Zhang, ... Molecular Cell 84 (14), 2601-2617. e12, 2024 | 2 | 2024 |
SMYD5 methylation of rpL40 links ribosomal output to gastric cancer J Park, J Wu, KJ Szkop, J Jeong, P Jovanovic, D Husmann, NM Flores, ... Nature, 1-8, 2024 | | 2024 |
Discovery of a Highly Potent and Selective HDAC8 Degrader: Advancing the Functional Understanding and Therapeutic Potential of HDAC8 Y Xiao, N Awasthee, Y Liu, C Meng, MY He, S Hale, R Karki, Z Lin, ... Journal of Medicinal Chemistry, 2024 | | 2024 |
ATP-dependent citrate lyase Drives Left Ventricular Dysfunction by Metabolic Remodeling of the Heart S Liu, ST Gammon, L Tan, Y Gao, K Kim, IK Williamson, J Pham, ... bioRxiv, 2024.06. 21.600099, 2024 | | 2024 |
Cancer-associated Histone H3 N-terminal arginine mutations disrupt PRC2 activity and impair differentiation BA Nacev, Y Dabas, MR Paul, C Pacheco, M Mitchener, Y Perez, Y Fang, ... Nature Communications 15 (1), 5155, 2024 | | 2024 |
MDB-10. DIVERGENT MEDULLOBLASTOMA CHROMATIN STATES DISCLOSE KDM2B AS A NOVEL ONCOGENIC DEPENDENCY R Tao, S Erkek, Y Matsui, B Xu, KS Smith, Q Gao, Y Li, N Djekidel, ... Neuro-Oncology 26 (Suppl 4), 0, 2024 | | 2024 |
Improved detection of DNA replication fork-associated proteins RS Rivard, YC Chang, RL Ragland, YM Thu, M Kassab, RS Mandal, ... Cell Reports 43 (5), 2024 | 2 | 2024 |
Harnessing molecular mechanism for precision medicine in dilated cardiomyopathy caused by a mutation in troponin T L Greenberg, WT Stump, Z Lin, AL Bredemeyer, T Blackwell, X Han, ... bioRxiv, 2024 | 1 | 2024 |
Signal improved ultra-fast light-sheet microscope for large tissue imaging MNH Prince, B Garcia, C Henn, Y Yi, EA Susaki, Y Watakabe, T Nemoto, ... Communications Engineering 3 (1), 59, 2024 | 1 | 2024 |
Histone butyrylation in the mouse intestine is mediated by the microbiota and associated with regulation of gene expression LA Gates, BS Reis, PJ Lund, MR Paul, M Leboeuf, AM Djomo, Z Nadeem, ... Nature Metabolism 6 (4), 697-707, 2024 | 2 | 2024 |
GPC2 directed CAR T cells are efficacious against fusion-positive and fusion-negative rhabdomyosarcomas R Shraim, PM Schuerch, AM Giudice, KL Conkrite, AK Weiner, ... Cancer Research 84 (6_Supplement), 1090-1090, 2024 | | 2024 |
Two DOT1 enzymes cooperatively mediate efficient ubiquitin-independent histone H3 lysine 76 tri-methylation in kinetoplastids VS Frisbie, H Hashimoto, Y Xie, FN De Luna Vitorino, J Baeza, T Nguyen, ... Nature Communications 15 (1), 2467, 2024 | | 2024 |
TGF-β controls alveolar type 1 epithelial cell plasticity and alveolar matrisome gene transcription in mice DA Callaway, IJ Penkala, S Zhou, JJ Knowlton, F Cardenas-Diaz, A Babu, ... The Journal of Clinical Investigation 134 (6), 2024 | 4 | 2024 |
Development and application of GlycanDIA workflow for glycomic analysis Y Xie, X Liu, C Zhao, S Chen, S Wang, Z Lin, FM Robison, BM George, ... bioRxiv, 2024 | | 2024 |
Erratum: Loss of epigenetic information as a cause of mammalian aging (Cell (2023) 186 (2)(305–326. e27),(S0092867422015707),(10.1016/j. cell. 2022.12. 027)) JH Yang, M Hayano, PT Griffin, JA Amorim, MS Bonkowski, ... Cell 187 (5), 1312-1313, 2024 | | 2024 |
H2A. Z histone variants facilitate HDACi-dependent removal of H3. 3K27M mutant protein in pediatric high-grade glioma cells KB Leszczynska, A Freitas-Huhtamäki, C Jayaprakash, M Dzwigonska, ... Cell reports 43 (2), 2024 | 1 | 2024 |
In utero pulse injection of isotopic amino acids quantifies protein turnover rates during murine fetal development J Baeza, BE Coons, Z Lin, J Riley, M Mendoza, WH Peranteau, BA Garcia Cell Reports Methods 4 (2), 2024 | | 2024 |
SIRT7 regulates NUCKS1 chromatin binding to elicit metabolic and inflammatory gene expression in senescence and liver aging K Tran, M Gilbert, BN Vazquez, A Ianni, BA Garcia, A Vaquero, S Berger bioRxiv, 2024 | | 2024 |
FLT3 tyrosine kinase inhibition modulates PRC2 and promotes differentiation in acute myeloid leukemia PJ Sung, M Selvam, SS Riedel, HM Xie, K Bryant, B Manning, ... Leukemia 38 (2), 291-301, 2024 | 2 | 2024 |