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Kenn Gerdes
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Diverse genetic contexts of HicA toxin domains propose a role in anti-phage defense
K Gerdes
Mbio 15 (2), e03293-23, 2024
2024
Structural basis for kinase inhibition in the tripartite E. coli HipBST toxin–antitoxin system
RL Bærentsen, SV Nielsen, RB Skjerning, J Lyngsø, F Bisiak, ...
Elife 12, RP90400, 2023
22023
Structural basis for regulation of a tripartite toxin-antitoxin system by dual phosphorylation
RL Bærentsen, SV Nielsen, J Lyngsø, F Bisiak, JS Pedersen, K Gerdes, ...
bioRxiv, 2022
22022
Proteome dynamics during antibiotic persistence and resuscitation
M Semanjski, FL Gratani, T Englert, P Nashier, V Beke, N Nalpas, ...
Msystems 6 (4), 10.1128/msystems. 00549-21, 2021
52021
Phylogeny reveals novel HipA-homologous kinase families and toxin-antitoxin gene organizations
K Gerdes, R Bærentsen, DE Brodersen
MBio 12 (3), 10.1128/mbio. 01058-21, 2021
92021
Structural Basis for Regulation of Toxin Activity via Dual Phosphorylation in the Tripartite HipBST Toxin‐Antitoxin System
R Baerentsen, S Nielsen, T Li, J Lyngsø, H Rasmussen, J Pedersen, ...
The FASEB Journal 35, 2021
2021
Corrigendum to article ‘Hibernation factors directly block ribonucleases from entering the ribosome in response to starvation’
T Prossliner, K Gerdes, MA Sørensen, KS Winther
Nucleic Acids Research 49 (6), 3599-3599, 2021
12021
Hibernation factors directly block ribonucleases from entering the ribosome in response to starvation
T Prossliner, K Gerdes, MA Sørensen, KS Winther
Nucleic Acids Research 49 (4), 2226-2239, 2021
322021
PasT of Escherichia coli sustains antibiotic tolerance and aerobic respiration as a bacterial homolog of mitochondrial Coq10
C Fino, M Vestergaard, H Ingmer, F Pierrel, K Gerdes, A Harms
MicrobiologyOpen 9 (8), e1064, 2020
142020
Type II and type IV toxin–antitoxin systems show different evolutionary patterns in the global Klebsiella pneumoniae population
G Horesh, C Fino, A Harms, MJ Dorman, L Parts, K Gerdes, E Heinz, ...
Nucleic Acids Research 48 (8), 4357-4370, 2020
202020
Proteome dynamics in persisting and resuscitating bacterial cells
M Semanjski, F Gratani, T Englert, V Beke, N Nalpas, E Germain, ...
bioRxiv, 2020
2020
The E. coli HicB antitoxin contains a structurally stable helix-turn-helix DNA binding domain
MC Manav, KJ Turnbull, D Jurėnas, A Garcia-Pino, K Gerdes, ...
Structure 27 (11), 1675-1685. e3, 2019
162019
Fatty acid starvation activates RelA by depleting lysine precursor pyruvate
AK Sinha, KS Winther, M Roghanian, K Gerdes
Molecular Microbiology 112 (4), 1339-1349, 2019
312019
CRP Interacts Specifically With Sxy to Activate Transcription in Escherichia coli
E Søndberg, AK Sinha, K Gerdes, S Semsey
Frontiers in microbiology 10, 2053, 2019
52019
Toxin–antitoxin operon kacAT of Klebsiella pneumoniae is regulated by conditional cooperativity via a W-shaped KacA–KacT complex
H Qian, H Yu, P Li, E Zhu, Q Yao, C Tai, Z Deng, K Gerdes, X He, J Gan, ...
Nucleic Acids Research 47 (14), 7690-7702, 2019
222019
Serine-Threonine Kinases Encoded by Split hipA Homologs Inhibit Tryptophanyl-tRNA Synthetase
S Vang Nielsen, KJ Turnbull, M Roghanian, R Bærentsen, M Semanjski, ...
MBio 10 (3), 10.1128/mbio. 01138-19, 2019
23*2019
(p) ppGpp regulates a bacterial nucleosidase by an allosteric two-domain switch
YE Zhang, RL Baerentsen, T Fuhrer, U Sauer, K Gerdes, DE Brodersen
Molecular cell 74 (6), 1239-1249. e4, 2019
462019
Stochastic induction of persister cells by HipA through (p) ppGpp-mediated activation of mRNA endonucleases (Retraction of Vol 112, Pg 5171, 2015)
E Germain, M Roghanian, K Gerdes, E Maisonneuve
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF …, 2019
2019
The RES domain toxins of RES‐Xre toxin‐antitoxin modules induce cell stasis by degrading NAD+
RB Skjerning, M Senissar, KS Winther, K Gerdes, DE Brodersen
Molecular microbiology 111 (1), 221-236, 2019
482019
SLING: a tool to search for linked genes in bacterial datasets
G Horesh, A Harms, C Fino, L Parts, K Gerdes, E Heinz, NR Thomson
Nucleic acids research 46 (21), e128-e128, 2018
262018
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Articles 1–20