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Jo Nyffeler (ORCiD 0000-0002-6155-9743)
Jo Nyffeler (ORCiD 0000-0002-6155-9743)
Other namesJohanna Nyffeler
Helmholtz-Zentrum für Umweltforschung GmbH - UFZ
Verified email at swissonline.ch
Title
Cited by
Year
In vitro bioassays for monitoring drinking water quality of tap water, domestic filtration and bottled water
BI Escher, J Blanco, J Caixach, D Cserbik, MJ Farré, C Flores, M König, ...
Journal of Exposure Science & Environmental Epidemiology, 1-10, 2023
32023
Application of Cell Painting for chemical hazard evaluation in support of screening-level chemical assessments
J Nyffeler, C Willis, FR Harris, MJ Foster, B Chambers, M Culbreth, ...
Toxicology and Applied Pharmacology 468, 116513, 2023
132023
Navigating Transcriptomic Connectivity Mapping Workflows to Link Chemicals with Bioactivities
I Shah, J Bundy, B Chambers, LJ Everett, D Haggard, J Harrill, RS Judson, ...
Chemical Research in Toxicology 35 (11), 1929-1949, 2022
62022
An expert-driven literature review of “negative” chemicals for developmental neurotoxicity (DNT) in vitro assay evaluation
MM Martin, NC Baker, WK Boyes, KE Carstens, ME Culbreth, ME Gilbert, ...
Neurotoxicology and Teratology 93, 107117, 2022
82022
Combining phenotypic profiling and targeted RNA-Seq reveals linkages between transcriptional perturbations and chemical effects on cell morphology: Retinoic acid as an example
J Nyffeler, C Willis, FR Harris, LW Taylor, R Judson, LJ Everett, JA Harrill
Toxicology and Applied Pharmacology 444, 116032, 2022
102022
Optimization of Human Neural Progenitor Cells for an Imaging-Based High-Throughput Phenotypic Profiling Assay for Developmental Neurotoxicity Screening
M Culbreth, J Nyffeler, C Willis, JA Harrill
Frontiers in Toxicology 3, 803987, 2022
22022
High-throughput phenotypic profiling within the NAMs-based, tiered hazard evaluation strategy at the United States Environmental Protection Agency
J Nyffeler, C Willis, M Culbreth, RE Brockway, LJ Everett, G Patlewicz, ...
Toxicology Letters 350, S61-S62, 2021
2021
Strategic Use of High-Throughput Transcriptomics and Phenotypic Profiling Data In Support of Regulatory Decisions
J Harrill, L Everett, J Nyffeler, C Willis, R Brockway, KP Freidman, I Shah, ...
Toxicology Letters 350, S46, 2021
2021
Comparison of Approaches for Determining Bioactivity Hits from High-Dimensional Profiling Data
J Nyffeler, DE Haggard, C Willis, RW Setzer, R Judson, K Paul-Friedman, ...
SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (2), 292-308, 2021
192021
Heritable Impacts of General Anesthesia: An Urgent Question for Genetic Toxicology and Autism Research.
D You, J Nyffeler, JA Harrill, C Willis, M Behl, T Choi, M Balik-Meisner, ...
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 61, 39-40, 2020
2020
Phenotypic Profiling of Reference Chemicals across Biologically Diverse Cell Types Using the Cell Painting Assay
C Willis, J Nyffeler, J Harrill
SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (7), 755-769, 2020
482020
Time and space-resolved quantification of plasma membrane sialylation for measurements of cell function and neurotoxicity
P Kranaster, C Karreman, JEGA Dold, A Krebs, M Funke, AK Holzer, ...
Archives of Toxicology 94, 449-467, 2020
102020
Determination of benchmark concentrations and their statistical uncertainty for cytotoxicity test data and functional in vitro assays
A Krebs, J Nyffeler, C Karreman, BZ Schmidt, F Kappenberg, J Mellert, ...
ALTEX-Alternatives to animal experimentation 37 (1), 155-163, 2020
262020
Bioactivity screening of environmental chemicals using imaging-based high-throughput phenotypic profiling
J Nyffeler, C Willis, R Lougee, A Richard, K Paul-Friedman, JA Harrill
Toxicology and Applied Pharmacology 389, 114876, 2020
832020
The synthetic peptide LyeTxI-b derived from Lycosa erythrognatha spider venom is cytotoxic to U-87 MG glioblastoma cells
MAL Abdel-Salam, J Carvalho-Tavares, KS Gomes, A Teixeira-Carvalho, ...
Amino Acids 51, 433-449, 2019
152019
Corrigendum to Normalization of data for viability and relative cell function curves.
A Krebs, J Nyffeler, J Rahnenführer, M Leist
ALTEX 36 (3), 505-505, 2019
22019
A structure–activity relationship linking non-planar PCBs to functional deficits of neural crest cells: new roles for connexins
J Nyffeler, P Chovancova, X Dolde, AK Holzer, V Purvanov, I Kindinger, ...
Archives of toxicology 92, 1225-1247, 2018
252018
Normalization of data for viability and relative cell function curves
A Krebs, J Nyffeler, J Rahnenführer, M Leist
Alternatives to Animal Experimentation: ALTEX 35 (2), 268-271, 2018
282018
Combination of multiple neural crest migration assays to identify environmental toxicants from a proof-of-concept chemical library
J Nyffeler, X Dolde, A Krebs, K Pinto-Gil, M Pastor, M Behl, T Waldmann, ...
Archives of toxicology 91, 3613-3632, 2017
432017
Impairment of human neural crest cell migration by prolonged exposure to interferon-beta
G Pallocca, J Nyffeler, X Dolde, M Grinberg, G Gstraunthaler, T Waldmann, ...
Archives of toxicology 91, 3385-3402, 2017
172017
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