| TRSC-04 DE NOVO GTP SYNTHESIS IS A METABOLIC VULNERABILITY FOR THE INTERCEPTION OF BRAIN METASTASES A Kieliszek, D Mobilio, B Bassey-Archibong, J Johnson, M Piotrowski, ... Neuro-Oncology Advances 6 (Suppl 1), i40, 2024 | | 2024 |
| Discovery of YSR734: A covalent HDAC inhibitor with cellular activity in acute myeloid leukemia and Duchenne muscular dystrophy YS Raouf, A Sedighi, M Geletu, GA Frere, RG Allan, N Nawar, ... Journal of Medicinal Chemistry 66 (24), 16658-16679, 2023 | 5 | 2023 |
| High-Affinity Fluorogenic Substrate for Tissue Transglutaminase Reveals Enzymatic Hysteresis EWJ Gates, A Prince-Hallée, Y Heidari, A Sedighi, JW Keillor Biochemistry 62 (21), 3085-3095, 2023 | 2 | 2023 |
| INTERCEPTING BRAIN METASTASES THROUGH METABOLIC VULNERABILITIES AM Kieliszek, D Mobilio, BI Bassey-Archibong, JW Johnson, ... Neuro-Oncology Advances 5 (Suppl 2), i2, 2023 | | 2023 |
| INSPIRE: Development of an Interdisciplinary Summer Program in Research and Entrepreneurship A Sedighi, T Radu, Q Ashraf, B Kumar, E Quilates, R Rahmatullah, ... | | 2023 |
| Blocking STAT3/5 through direct or upstream kinase targeting in leukemic cutaneous T‐cell lymphoma H Sorger, S Dey, PA Vieyra‐Garcia, D Pölöske, AR Teufelberger, ... EMBO Molecular Medicine 14 (12), e15200, 2022 | 14 | 2022 |
| High Efficacy and Drug Synergy of HDAC6-Selective Inhibitor NN-429 in Natural Killer (NK)/T-Cell Lymphoma HK Garcha, N Nawar, H Sorger, F Erdogan, MMK Aung, A Sedighi, ... Pharmaceuticals 15 (11), 1321, 2022 | | 2022 |
| Evaluation of Small-Molecule HDAC Inhibitors Through In Vitro and In Cellulo Approaches N Nawar, HK Garcha, A Sedighi, ED de Araujo, PT Gunning HDAC/HAT Function Assessment and Inhibitor Development: Methods and …, 2022 | | 2022 |
| Phenotypic Screening of Histone Deacetylase (HDAC) Inhibitors against Schistosoma mansoni MM Hassan, A Sedighi, OO Olaoye, C Häberli, A Merz, E Ramos‐Morales, ... ChemMedChem 17 (18), e202100622, 2022 | 5 | 2022 |
| The genetic authentication of Panax ginseng and Panax quinquefolius based on using single nucleotide polymorphism (SNP) conducted in a nucleic acid test chip C Oberc, A Sedighi, PCH Li Analytical and Bioanalytical Chemistry 414 (13), 3987-3998, 2022 | 4 | 2022 |
| Discovery of HDAC6-Selective Inhibitor NN-390 with in Vitro Efficacy in Group 3 Medulloblastoma N Nawar, S Bukhari, AA Adile, Y Suk, P Manaswiyoungkul, K Toutah, ... Journal of medicinal chemistry 65 (4), 3193-3217, 2022 | 19 | 2022 |
| Development of HDAC inhibitors exhibiting therapeutic potential in T-cell prolymphocytic leukemia K Toutah, N Nawar, S Timonen, H Sorger, YS Raouf, S Bukhari, J von Jan, ... Journal of medicinal chemistry 64 (12), 8486-8509, 2021 | 29 | 2021 |
| Unique molecular interaction with the histone deacetylase 6 catalytic tunnel: crystallographic and biological characterization of a model chemotype OO Olaoye, PR Watson, N Nawar, M Geletu, A Sedighi, S Bukhari, ... Journal of medicinal chemistry 64 (5), 2691-2704, 2021 | 18 | 2021 |
| PTG-0861: A novel HDAC6-selective inhibitor as a therapeutic strategy in acute myeloid leukaemia JM Gawel, AE Shouksmith, YS Raouf, N Nawar, K Toutah, S Bukhari, ... European Journal of Medicinal Chemistry 201, 112411, 2020 | 39 | 2020 |
| Abstract LB-108: A potent and selective small molecule degrader of STAT5 for the treatment of hematological malignancies JS Park, G Tin, ED de Araujo, A Orlova, H Sorger, F Grebien, E Heyes, ... Cancer Research 80 (16_Supplement), LB-108-LB-108, 2020 | 6 | 2020 |
| Characterization of conformationally constrained benzanilide scaffolds for potent and selective HDAC8 targeting MM Hassan, J Israelian, N Nawar, G Ganda, P Manaswiyoungkul, ... Journal of Medicinal Chemistry 63 (15), 8634-8648, 2020 | 35 | 2020 |
| Bisphosphonate polymeric ligands on inorganic nanoparticles K Malhotra, R Fuku, TS Chan, N Kraljevic, A Sedighi, PAE Piunno, ... Chemistry of Materials 32 (9), 4002-4012, 2020 | 21 | 2020 |
| Multifunctional droplet microfluidic platform for rapid immobilization of oligonucleotides on semiconductor quantum dots TH Nguyen, A Sedighi, UJ Krull, CL Ren ACS sensors 5 (3), 746-753, 2020 | 8 | 2020 |
| Class I/IIb-selective HDAC inhibitor exhibits oral bioavailability and therapeutic efficacy in acute myeloid leukemia AE Shouksmith, JM Gawel, N Nawar, D Sina, YS Raouf, S Bukhari, L He, ... ACS Medicinal Chemistry Letters 11 (1), 56-64, 2019 | 26 | 2019 |
| Enhanced immunoassay using a rotating paper platform for quantitative determination of low abundance protein biomarkers A Sedighi, UJ Krull Analytical chemistry 91 (8), 5371-5379, 2019 | 6 | 2019 |
