Fragmentation landscape of cell-free DNA revealed by deconvolutional analysis of end motifs Z Zhou, MJL Ma, RWY Chan, WKJ Lam, W Peng, W Gai, X Hu, SC Ding, ... Proceedings of the National Academy of Sciences 120 (17), e2220982120, 2023 | 16 | 2023 |
Fragment ends of circulating microbial DNA as signatures for pathogen detection in sepsis G Wang, WKJ Lam, L Ling, MJL Ma, S Ramakrishnan, DCT Chan, ... Clinical Chemistry 69 (2), 189-201, 2023 | 5 | 2023 |
Comparison of single molecule, real-time sequencing and nanopore sequencing for analysis of the size, end-motif, and tissue-of-origin of long cell-free DNA in plasma SCY Yu, J Deng, R Qiao, SH Cheng, W Peng, SL Lau, LYL Choy, ... Clinical chemistry 69 (2), 168-179, 2023 | 25 | 2023 |
Epigenetic analysis of cell-free DNA by fragmentomic profiling Q Zhou, G Kang, P Jiang, R Qiao, WKJ Lam, SCY Yu, MJL Ma, L Ji, ... Proceedings of the National Academy of Sciences 119 (44), e2209852119, 2022 | 35 | 2022 |
Single-molecule sequencing enables long cell-free DNA detection and direct methylation analysis for cancer patients LYL Choy, W Peng, P Jiang, SH Cheng, SCY Yu, H Shang, OY Olivia Tse, ... Clinical Chemistry 68 (9), 1151-1163, 2022 | 33 | 2022 |
The next frontier in noninvasive prenatal diagnostics: cell-free fetal DNA analysis for monogenic disease assessment LPW Zhong, RWK Chiu Annual Review of Genomics and Human Genetics 23 (1), 413-425, 2022 | 7 | 2022 |
Fragmentomics of urinary cell-free DNA in nuclease knockout mouse models M Chen, RWY Chan, PPH Cheung, M Ni, DKL Wong, Z Zhou, MJL Ma, ... PLoS Genetics 18 (7), e1010262, 2022 | 9 | 2022 |
Jagged ends on multinucleosomal cell-free DNA serve as a biomarker for nuclease activity and systemic lupus erythematosus SC Ding, RWY Chan, W Peng, L Huang, Z Zhou, X Hu, S Volpi, LT Hiraki, ... Clinical Chemistry 68 (7), 917-926, 2022 | 7 | 2022 |
Effects of nucleases on cell-free extrachromosomal circular DNA STK Sin, J Deng, L Ji, M Yukawa, RWY Chan, S Volpi, A Vaglio, ... JCI insight 7 (8), 2022 | 18 | 2022 |
High-resolution analysis for urinary DNA jagged ends T Xie, G Wang, SC Ding, WS Lee, SH Cheng, RWY Chan, Z Zhou, ... NPJ Genomic Medicine 7 (1), 14, 2022 | 5 | 2022 |
Single-molecule sequencing reveals a large population of long cell-free DNA molecules in maternal plasma SCY Yu, P Jiang, W Peng, SH Cheng, YTT Cheung, OYO Tse, H Shang, ... Proceedings of the National Academy of Sciences 118 (50), e2114937118, 2021 | 49 | 2021 |
Nuclease deficiencies alter plasma cell-free DNA methylation profiles DSC Han, M Ni, RWY Chan, DKL Wong, LT Hiraki, S Volpi, P Jiang, ... Genome Research 31 (11), 2008-2021, 2021 | 6 | 2021 |
Single cell and plasma RNA sequencing for RNA liquid biopsy for hepatocellular carcinoma JSL Vong, L Ji, MMS Heung, SH Cheng, J Wong, PBS Lai, VWS Wong, ... Clinical Chemistry 67 (11), 1492-1502, 2021 | 12 | 2021 |
Cell‐free fetal DNA coming in all sizes and shapes RWK Chiu, YMD Lo Prenatal Diagnosis 41 (10), 1193-1201, 2021 | 21 | 2021 |
International Society for Prenatal Diagnosis Position Statement: cell free (cf) DNA screening for Down syndrome in multiple pregnancies GE Palomaki, RWK Chiu, MD Pertile, EA Sistermans, Y Yaron, ... Prenatal diagnosis 41 (10), 1222-1232, 2021 | 58 | 2021 |
Dissection of PIK3CA Aberration for Cervical Adenocarcinoma Outcomes TKH Chung, G Doran, TH Cheung, SF Yim, MY Yu, MJ Worley Jr, ... Cancers 13 (13), 3218, 2021 | 3 | 2021 |
Characteristics of fetal extrachromosomal circular DNA in maternal plasma: methylation status and clearance STK Sin, L Ji, J Deng, P Jiang, SH Cheng, MMS Heung, CSL Lau, ... Clinical chemistry 67 (5), 788-796, 2021 | 29 | 2021 |
Epigenetics, fragmentomics, and topology of cell-free DNA in liquid biopsies YMD Lo, DSC Han, P Jiang, RWK Chiu Science 372 (6538), eaaw3616, 2021 | 333 | 2021 |
Jagged ends of urinary cell-free DNA: characterization and feasibility assessment in bladder cancer detection Z Zhou, SH Cheng, SC Ding, MMS Heung, T Xie, THT Cheng, WKJ Lam, ... Clinical Chemistry 67 (4), 621-630, 2021 | 29 | 2021 |
Applications of genetic-epigenetic tissue mapping for plasma DNA in prenatal testing, transplantation and oncology W Gai, Z Zhou, S Agbor-Enoh, X Fan, S Lian, P Jiang, SH Cheng, J Wong, ... Elife 10, e64356, 2021 | 23 | 2021 |