Using LDDMM and a kinematic cardiac growth model to quantify growth and remodelling in rat hearts under PAH D Guan, L Tian, W Li, H Gao Computers in Biology and Medicine 171, 108218, 2024 | | 2024 |
The effects of mitochondrial dysfunction on the cell cycle D Wu, L Tian, V Hoskin, A Dasgupta Frontiers in Cell and Developmental Biology 11, 1303834, 2023 | | 2023 |
Upregulation of Dynamin 2 Increases Mitochondrial Fission and Cell Proliferation in Pulmonary Arterial Hypertension A Das Gupta, KH Chen, D Wu, J Mewburn, P Lima, R Al-Qazazi, A Martin, ... Circulation 146 (Suppl_1), A11484-A11484, 2022 | | 2022 |
An integrated proteomic and transcriptomic signature of the failing right ventricle in monocrotaline induced pulmonary arterial hypertension in male rats CCT Hindmarch, L Tian, PY Xiong, F Potus, RET Bentley, R Al-Qazazi, ... Frontiers in Physiology 13, 966454, 2022 | 9 | 2022 |
Macrophage–NLRP3 activation promotes right ventricle failure in pulmonary arterial hypertension R Al-Qazazi, PDA Lima, SZ Prisco, F Potus, A Dasgupta, KH Chen, L Tian, ... American journal of respiratory and critical care medicine 206 (5), 608-624, 2022 | 59 | 2022 |
Growth and Remodelling of Right Ventricle Under Pulmonary Arterial Hypertension D Guan, L Tian, H Gao | | 2022 |
Inhibiting pyruvate kinase muscle isoform 2 regresses group 2 pulmonary hypertension induced by supra‐coronary aortic banding PY Xiong, M Motamed, KH Chen, A Dasgupta, F Potus, L Tian, A Martin, ... Acta Physiologica 234 (2), e13764, 2022 | 6 | 2022 |
NLRP3 inflammasome activation in macrophages drives adverse right ventricular remodeling and dysfunction PD Lima, R Al-qazazi, SZ Prisco, F Potus, A Das Gupta, KH Chen, L Tian, ... Circulation 144 (Suppl_1), A13924-A13924, 2021 | 1 | 2021 |
An Epigenetic Upregulation of Dynamin 2, a Regulator of Mitochondrial Fission, Promotes Human and Experimental Pulmonary Arterial Hypertension A Das Gupta, KH Chen, L Tian, D Wu, J Mewburn, P Lima, SL Archer Circulation 144 (Suppl_1), A12932-A12932, 2021 | 1 | 2021 |
Integration of Proteomic and Transcriptomic Signatures in the Failing Right Ventricle of Rats With Monocrotaline Induced Pulmonary Arterial Hypertension CC Hindmarch, L Tian, PY Xiong, F Potus, R Bentley, R Al-qazazi, ... Circulation 144 (Suppl_1), A13792-A13792, 2021 | | 2021 |
An epigenetic upregulation of dynamin 2, a regulator of mitochondrial fission, promotes human and experimental pulmonary arterial hypertension L Tian AHA Scientific Sessions, 2021 | | 2021 |
Integration of proteomic and transcriptomic signatures in the failing right ventricle of rats with monocrotaline induced pulmonary arterial hypertension L Tian AHA Scientific Sessions, 2021 | | 2021 |
PINK1 induced phosphorylation of mitofusin 2 (Mfn2) at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial … A Dasgupta, KH Chen, PDA Lima, J Mewburn, D Wu, R Al-Qazazi, ... FASEB journal: official publication of the Federation of American Societies …, 2021 | 32 | 2021 |
Oxygen sensing, mitochondrial biology and experimental therapeutics for pulmonary hypertension and cancer D Wu, A Dasgupta, AD Read, RET Bentley, M Motamed, KH Chen, ... Free Radical Biology and Medicine 170, 150-178, 2021 | 44 | 2021 |
Inhibiting Pyruvate Kinase Muscle Isoform 2 Regresses Group 2 Pulmonary Hypertension Induced by Supra-coronary Aortic Banding PY Xiong, M Motamed, KH Chen, A Dasgupta, F Potus, L Tian, A Martin, ... CIRCULATION RESEARCH 127 (12), E275-E275, 2020 | | 2020 |
Excess protein O-GlcNAcylation links metabolic derangements to right ventricular dysfunction in pulmonary arterial hypertension SZ Prisco, L Rose, F Potus, L Tian, D Wu, L Hartweck, R Al-Qazazi, ... International journal of molecular sciences 21 (19), 7278, 2020 | 19 | 2020 |
Supra‐coronary aortic banding improves right ventricular function in experimental pulmonary arterial hypertension in rats by increasing systolic right coronary artery perfusion L Tian, PY Xiong, E Alizadeh, PDA Lima, F Potus, J Mewburn, A Martin, ... Acta Physiologica 229 (4), e13483, 2020 | 15 | 2020 |
Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension F Potus, MW Pauciulo, EK Cook, N Zhu, A Hsieh, CL Welch, Y Shen, ... Circulation 141 (24), 1986-2000, 2020 | 101 | 2020 |
Epigenetic metabolic reprogramming of right ventricular fibroblasts in pulmonary arterial hypertension: a pyruvate dehydrogenase kinase-dependent shift in mitochondrial … L Tian, D Wu, A Dasgupta, KH Chen, J Mewburn, F Potus, PDA Lima, ... Circulation research 126 (12), 1723-1745, 2020 | 102 | 2020 |
Inhibiting pyruvate kinase muscle isoform 2 with shikonin regresses supra-coronary aortic banding induced group 2 pulmonary hypertension L Tian American Thoracic Society (ATS) Conference 2020, 2020 | | 2020 |