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David R. Snead
David R. Snead
Director, Chemical Process Research and Development
Verified email at mirati.com
Title
Cited by
Year
A Concise Route to MK-4482 (EIDD-2801)
N Vasudevan, GP Ahlqvist, CP McGeough, DJ Paymode, FSP Cardoso, ...
2020
A concise route to MK-4482 (EIDD-2801) from cytidine
N Vasudevan, GP Ahlqvist, CP McGeough, DJ Paymode, FSP Cardoso, ...
Chemical Communications 56 (87), 13363-13364, 2020
552020
A Concise Route to MK-4482 (EIDD-2801) from Cytidine: Part 2
V Gopalsamuthiram, C Williams, J Noble, TF Jamison, BF Gupton, ...
Synlett 32 (03), 326-328, 2021
342021
A Continuous Flow Sulfuryl Chloride-Based Reaction—Synthesis of a Key Intermediate in a New Route toward Emtricitabine and Lamivudine
JM de Souza, M Berton, DR Snead, DT McQuade
Organic Process Research & Development 24 (10), 2271-2280, 2020
72020
A high‐yielding synthesis of EIDD‐2801 from Uridine
A Steiner, D Znidar, SB Ötvös, DR Snead, D Dallinger, CO Kappe
European Journal of Organic Chemistry 2020 (43), 6736-6739, 2020
352020
A new route to acyclic diaminocarbenes via lithium− halogen exchange
DR Snead, I Ghiviriga, KA Abboud, S Hong
Organic Letters 11 (15), 3274-3277, 2009
472009
A Practical and Economical Route to (S)-Glycidyl Pivalate
JM Noble, L Chang, D Chen, B Wang, RN Dominey, DW Cook, JM Burns, ...
SynOpen 6 (04), 258-262, 2022
22022
A three‐minute synthesis and purification of ibuprofen: Pushing the limits of continuous‐flow processing
DR Snead, TF Jamison
Angewandte Chemie International Edition 54 (3), 983-987, 2015
2572015
Access to Cyclopropanol via Supply-Centered Synthesis
DR Snead, Y Wang, S Liu, L Lin
Organic Process Research & Development 28 (5), 1830-1837, 2024
2024
Adagrasib’s Second-Generation Synthesis: Transitioning from Route Scouting to Optimization
Z Lu, C Chen, DJ Paymode, Y Gan, T Scattolin, S Roshandel, W Dong, ...
Organic Process Research & Development, 2024
2024
An economical route to lamivudine featuring a novel strategy for stereospecific assembly
DR Snead, DT McQuade, S Ahmad, R Krack, RW Stringham, JM Burns, ...
Organic Process Research & Development 24 (6), 1194-1198, 2020
162020
An efficient synthesis of tenofovir (PMPA): A key intermediate leading to tenofovir-based HIV medicines
BP Derstine, JW Tomlin, CL Peck, JP Dietz, BT Herrera, FSP Cardoso, ...
Organic Process Research & Development 24 (8), 1420-1427, 2020
232020
An improved Balz-Schiemann reaction enabled by ionic liquids and continuous processing
DR Snead, F Lévesque, WJ Morris, JR Naber
Tetrahedron 75 (32), 4261-4265, 2019
122019
Application of vinamidinium salt chemistry for a palladium free synthesis of anti-malarial MMV048: A “bottom-up” approach
DJ Paymode, L Chang, D Chen, B Wang, K Kashinath, ...
Organic Letters 23 (14), 5400-5404, 2021
82021
Bis (2-alkylpyrrolidin-1-yl) methylidenes as chiral acyclic diaminocarbene ligands
DR Snead, S Inagaki, KA Abboud, S Hong
Organometallics 29 (7), 1729-1739, 2010
572010
Bulky acyclic aminooxycarbene ligands
H Seo, DR Snead, KA Abboud, S Hong
Organometallics 30 (21), 5725-5730, 2011
322011
Catalysts, methods of making catalysts, and methods of use
S Hong, HM Seo, DR Snead
US Patent 8,901,336, 2014
2014
Cationic collectors with mixed polyamidoamines and methods for making and using same
DR Snead
US Patent App. 14/920,844, 2016
32016
Continuous-flow synthesis and purification of atropine with sequential in-line separations of structurally similar impurities
C Dai, DR Snead, P Zhang, TF Jamison
Journal of Flow Chemistry 5, 133-138, 2015
522015
Correction to “Toward a Practical, Nonenzymatic Process for Investigational COVID-19 Antiviral Molnupiravir from Cytidine: Supply-Centered Synthesis”
V Gopalsamuthiram, AL Kadam, JM Noble, DR Snead, C Williams, ...
Organic Process Research & Development 27 (7), 1420-1420, 2023
2023
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