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Sepehr Dehghani-Ghahnaviyeh
Sepehr Dehghani-Ghahnaviyeh
Senior Scientist at Novartis Institutes for BioMedical Research
Verified email at novartis.com
Title
Cited by
Year
A Novel Grid-Based Molecular Dynamics Protocol to Shuffle Lipids in Heterogenious Membranes
S Dehghanighahnaviyeh, G Licari, E Tajkhorshid
Biophysical Journal 120 (3), 80a, 2021
2021
Backbone amides are determinants of Cl selectivity in CLC ion channels
L Leisle, K Lam, S Dehghani-Ghahnaviyeh, E Fortea, JD Galpin, ...
Nature communications 13 (1), 7508, 2022
32022
Complex self-propelled rings: a minimal model for cell motility
CA Velasco, SD Ghahnaviyeh, HN Pishkenari, T Auth, G Gompper
Soft Matter 13 (35), 5865-5876, 2017
312017
Conformational changes in the nucleotide‐binding domains of P‐glycoprotein induced by ATP hydrolysis
S Dehghani‐Ghahnaviyeh, K Kapoor, E Tajkhorshid
FEBS letters 595 (6), 735-749, 2021
172021
Conformational Coupling to Asymmetric ATP Hydrolysis in the Transport Cycle of P-Glycoprotein
S Dehghani-Ghahnaviyeh, K Kapoor, E Tajkhorshid
Biophysical Journal 116 (3), 126a, 2019
2019
Cryo‐EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms
LTM Le, JR Thompson, S Dehghani‐Ghahnaviyeh, S Pant, PX Dang, ...
The EMBO Journal 42 (3), e111065, 2023
82023
Differential dynamics and direct interaction of bound ligands with lipids in multidrug transporter ABCG2
A Rasouli, Q Yu, S Dehghani-Ghahnaviyeh, PC Wen, J Kowal, KP Locher, ...
Proceedings of the National Academy of Sciences 120 (1), e2213437120, 2023
152023
Direct lipid-drug interaction in human multidrug transporter ABCG2
A Rasouli, S Dehghanighahnaviyeh, Q Yu, PC Wen, K Locher, ...
Biophysical Journal 121 (3), 313a, 2022
2022
Dissecting the Interaction Fingerprints and Binding Affinity of BYL719 Analogs Targeting PI3Kα
S Dehghani-Ghahnaviyeh, C Soylu, P Furet, C Velez-Vega
The Journal of Physical Chemistry B 128 (8), 1819-1829, 2024
2024
EFFECT OF DIFFERENT GEOMETRICAL PARAMETERS OF ATOMIC FORCE MICROSCOPE CANTILEVERS IN CRITICAL FORCE AND TIME BASED ON MANIPULATION BY APPLYING EFAST SENSITIVITY ANALYSES
KM HABIBNEJAD, GS DEHGHANI, M Ghasemi, M Taheri
Modares Mechanical Engineering 15 (1), 310-316, 2015
62015
Interactions between ionizable amino lipids and a short RNA hairpin: Insights from molecular dynamics simulations for lipid nanoparticle optimization
AJ Poruthoor, S Dehghanighahnaviyeh, SK Bali, M Isik, S Sur
Biophysical Journal 123 (3), 97a, 2024
2024
Ionizable amino lipids distribution and effects on DSPC/cholesterol membranes: implications for lipid nanoparticle structure
S Dehghani-Ghahnaviyeh, M Smith, Y Xia, A Dousis, A Grossfield, S Sur
The Journal of Physical Chemistry B 127 (31), 6928-6939, 2023
92023
Lipid-mediated prestin organization in outer hair cell membranes and its implications in sound amplification
S Dehghani-Ghahnaviyeh, Z Zhao, E Tajkhorshid
Nature communications 13 (1), 6877, 2022
92022
Locked in place: Deciphering the conformational impairment caused by tumor-acquired somatic mutation Q393K in ABCG2
A Rasouli, T Gose, S Dehghani-Ghahnaviyeh, PC Wen, Y Wang, J Lynch, ...
Biophysical Journal 123 (3), 119a, 2024
2024
Martini 3 Force Field Parameters for Protein Lipidation Post-Translational Modifications
PI Koukos, S Dehghani-Ghahnaviyeh, C Velez-Vega, J Manchester, ...
Journal of Chemical Theory and Computation 19 (23), 8901-8918, 2023
22023
Mechanistic Picture for Structural Transition of P-Glycoprotein during the Transport Cycle
S Dehghanighahnaviyeh, K Kapoor, E Tajkhorshid
Biophysical Journal 118 (3), 366a, 2020
2020
Membrane mixer: a toolkit for efficient shuffling of lipids in heterogeneous biological membranes
G Licari, S Dehghani-Ghahnaviyeh, E Tajkhorshid
Journal of chemical information and modeling 62 (4), 986-996, 2022
212022
Modeling and simulation of three dimensional manipulations of biological micro/nanoparticles by applying cylindrical contact mechanics models by means of AFM
MH Korayem, MB Saraee, Z Mahmoodi, S Dehghani
Journal of Nanoparticle Research 17, 1-17, 2015
132015
Molecular mechanism of prestin electromotive signal amplification
J Ge, J Elferich, S Dehghani-Ghahnaviyeh, Z Zhao, M Meadows, ...
Cell 184 (18), 4669-4679. e13, 2021
642021
Molecular mechanism of sound amplification in mammalian hearing system
S Dehghani-Ghahnaviyeh, Z Zhao, E Tajkhorshid
Biophysical Journal 121 (3), 78a, 2022
2022
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