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Lukas Chavez
Lukas Chavez
Associate Professor, Department of Medicine, University of California, San Diego (UCSD)
Verified email at ucsd.edu - Homepage
Title
Cited by
Year
17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells
BJ Schmiedel, G Seumois, D Samaniego-Castruita, J Cayford, V Schulten, ...
Nature communications 7 (1), 13426, 2016
1142016
22. MEDIPS-‐computational analysis of genome-‐wide methylation using high-‐throughput sequencing
L Chavez, J Dietrich, M Vilardell-Nogales, R Herwig
MC Business Meeting and Scientific Meeting Brussels, 7-9 November 2011, 35, 0
3D genome conformation analysis in ST-EPN-ZFTA ependymoma identifies RCOR2 as a potential target
A Camgoez, K Okonechnikov, O Chapman, M Maurmann, F Buchholz, ...
Cancer Research 82 (12_Supplement), 3886-3886, 2022
2022
3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma
K Okonechnikov, A Camgöz, O Chapman, S Wani, DE Park, JM Hübner, ...
Nature Communications 14 (1), 2300, 2023
42023
A biobank of patient-derived pediatric brain tumor models
S Brabetz, SES Leary, SN Gröbner, MW Nakamoto, H Şeker-Cin, ...
Nature medicine 24 (11), 1752-1761, 2018
1492018
A data integration approach to mapping OCT4 gene regulatory networks operative in embryonic stem cells and embryonal carcinoma cells
M Jung, H Peterson, L Chavez, P Kahlem, H Lehrach, J Vilo, J Adjaye
PLoS One 5 (5), e10709, 2010
1052010
A mouse model for embryonal tumors with multilayered rosettes uncovers the therapeutic potential of Sonic-hedgehog inhibitors
JE Neumann, AK Wefers, S Lambo, E Bianchi, M Bockstaller, ...
Nature medicine 23 (10), 1191-1202, 2017
492017
A probabilistic generative model for quantification of DNA modifications enables analysis of demethylation pathways
T Äijö, Y Huang, H Mannerström, L Chavez, A Tsagaratou, A Rao, ...
Genome Biology 17, 1-22, 2016
172016
A probabilistic model for accurate quantification of DNA methylation modifications.
T Äijö, Y Huang, H Mannerström, L Chavez, A Tsagaratou, A Rao, ...
2016
A Transcriptional State Driven by Yin Yang 1 Confers a Therapeutic Vulnerability in Glioblastoma Stem Cells
Z Qiu, L Zhao, Z Liang, JZ Shen, K Yang, L Min, Q Wu, RC Gimple, ...
A110 LATE BREAKING ABSTRACTS IN DISEASE SUSCEPTIBILITY AND PATHOGENESIS: Epigenomic Analysis Of Primary Human T Cells Reveals Novel Enhancers Associated With Th2 Memory …
G Seumois, L Chavez, A Gerasimova, B Peters, A Rao, P Vijayanand
American Journal of Respiratory and Critical Care Medicine 189, 1, 2014
2014
Aberrant ERBB4-SRC signaling as a hallmark of group 4 medulloblastoma revealed by integrative phosphoproteomic profiling
A Forget, L Martignetti, S Puget, L Calzone, S Brabetz, D Picard, ...
Cancer cell 34 (3), 379-395. e7, 2018
1372018
About novoseek
M Jung, H Peterson, L Chavez, P Kahlem, H Lehrach, J Vilo, J Adjaye
Abstract B21: Childhood Cancer Molecular Map (C2M2) to define medulloblastoma heterogeneity and predict treatment response
H Yeerna, B Briggs, J Rusert, L Chavez, J Mesirov, R Wechsler-Reya, ...
Cancer Research 80 (14_Supplement), B21-B21, 2020
2020
Abstract B73: Second-generation molecular subgrouping of medulloblastoma: An international meta-analysis of Group 3 and Group 4 subtypes
T Sharma, EC Schwalbe, DW Williamson, M Sill, V Hovestadt, M Mynarek, ...
Cancer Research 80 (14_Supplement), B73-B73, 2020
2020
Abstract SY05-03: Circular extrachromosomal DNA promotes tumor heterogeneity and enhancer rewiring
L Chavez
Cancer Research 84 (7_Supplement), SY05-03-SY05-03, 2024
2024
Abstract SY15-02: Identification of novel oncogenic mechanisms in brain tumors with quiet genomes through mapping the enhancer landscape
S Erkek, KW Pajtler, PD Johann, PA Northcott, L Chavez, M Kool, ...
Cancer Research 76 (14_Supplement), SY15-02-SY15-02, 2016
2016
Active medulloblastoma enhancers reveal subgroup-specific cellular origins
CY Lin, S Erkek, Y Tong, L Yin, AJ Federation, M Zapatka, P Haldipur, ...
Nature 530 (7588), 57-62, 2016
3982016
Acute loss of TET function results in aggressive myeloid cancer in mice
J An, E González-Avalos, A Chawla, M Jeong, IF López-Moyado, W Li, ...
Nature communications 6 (1), 10071, 2015
1862015
An accessible GenePattern notebook for the copy number variation analysis of Illumina Infinium DNA methylation arrays
CK Mah, JP Mesirov, L Chavez
F1000Research 7, 2018
52018
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