Immunoresponsive gene 1 augments bactericidal activity of macrophage-lineage cells by regulating β-oxidation-dependent mitochondrial ROS production CJ Hall, RH Boyle, JW Astin, MV Flores, SH Oehlers, LE Sanderson, ... Cell metabolism 18 (2), 265-278, 2013 | 248 | 2013 |
Infection-responsive expansion of the hematopoietic stem and progenitor cell compartment in zebrafish is dependent upon inducible nitric oxide CJ Hall, MV Flores, SH Oehlers, LE Sanderson, EY Lam, KE Crosier, ... Cell stem cell 10 (2), 198-209, 2012 | 135 | 2012 |
Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders M Martin, S Vermeiren, N Bostaille, M Eubelen, D Spitzer, M Vermeersch, ... Science 375 (6582), eabm4459, 2022 | 98 | 2022 |
Blocking fatty acid–fueled mROS production within macrophages alleviates acute gouty inflammation CJ Hall, LE Sanderson, LM Lawrence, B Pool, M Van Der Kroef, ... The Journal of clinical investigation 128 (5), 1752-1771, 2018 | 61 | 2018 |
An inducible transgene reports activation of macrophages in live zebrafish larvae LE Sanderson, AT Chien, JW Astin, KE Crosier, PS Crosier, CJ Hall Developmental & Comparative Immunology 53 (1), 63-69, 2015 | 49 | 2015 |
Bi-allelic variants in HOPS complex subunit VPS41 cause cerebellar ataxia and abnormal membrane trafficking LE Sanderson, K Lanko, M Alsagob, R Almass, N Al-Ahmadi, M Najafi, ... Brain 144 (3), 769-780, 2021 | 38 | 2021 |
Mitochondrial metabolism, reactive oxygen species, and macrophage function-fishing for insights CJ Hall, LE Sanderson, KE Crosier, PS Crosier Journal of molecular medicine 92, 1119-1128, 2014 | 34 | 2014 |
Innate immune cells and bacterial infection in zebrafish JW Astin, P Keerthisinghe, L Du, LE Sanderson, KE Crosier, PS Crosier, ... Methods in cell biology 138, 31-60, 2017 | 30 | 2017 |
Dominant-acting CSF1R variants cause microglial depletion and altered astrocytic phenotype in zebrafish and adult-onset leukodystrophy WM Berdowski, HC van der Linde, M Breur, N Oosterhof, S Beerepoot, ... Acta Neuropathologica 144 (2), 211-239, 2022 | 23 | 2022 |
Bi‐allelic VPS16 variants limit HOPS/CORVET levels and cause a mucopolysaccharidosis‐like disease K Sofou, K Meier, LE Sanderson, D Kaminski, L Montoliu‐Gaya, ... EMBO molecular medicine 13 (5), e13376, 2021 | 19 | 2021 |
CD44-mediated hyaluronan binding marks proliferating hematopoietic progenitor cells and promotes bone marrow engraftment SSM Lee-Sayer, MN Dougan, J Cooper, L Sanderson, M Dosanjh, ... PloS one 13 (4), e0196011, 2018 | 19 | 2018 |
The multicellular interplay of microglia in health and disease: Lessons from leukodystrophy WM Berdowski, LE Sanderson, TJ van Ham Disease models & mechanisms 14 (8), dmm048925, 2021 | 11 | 2021 |
Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders. Science 375, eabm4459 M Martin, S Vermeiren, N Bostaille, M Eubelen, D Spitzer, M Vermeersch, ... | 10 | 2022 |
AMFR dysfunction causes autosomal recessive spastic paraplegia in human that is amenable to statin treatment in a preclinical model R Deng, E Medico-Salsench, A Nikoncuk, R Ramakrishnan, K Lanko, ... Acta Neuropathologica 146 (2), 353-368, 2023 | 8 | 2023 |
Autosomal recessive BLOC1S1 variants cause a hypomyelinating leukodystrophy with epileptic encephalopathy CD Gonzalez, LE Sanderson, R Depace, G Helman, K Wu, B Disanza, ... Molecular Genetics and Metabolism 141 (4), 108328, 2024 | | 2024 |
The non-canonical thioreductase TMX2 is essential for neuronal survival during embryonic brain development J Dekker, W Lam, R Schot, F Ophorst, HC van der Linde, L Sanderson, ... bioRxiv, 2024.06. 18.599494, 2024 | | 2024 |
Loss-of-function of AMFR causes autosomal recessive hereditary spastic paraplegia by altering lipid metabolism R Deng, EM Salsench, A Nikoncuk, N Kuhn, R Ramakrishnan, K Lanko, ... | | 2023 |
barakatlab/AMFR_paper: Figures R Deng, E Medico-Salsench, A Nikoncuk, R Ramakrishnan, K Lanko, ... Github, 2022 | | 2022 |
Bi-allelic variants in HOPS subunit VPS41 cause cerebellar ataxia and point to differential lysosomal dysregulation in brain cell types LE Sanderson, K Lanko, M Alsagob, R AlMass, N Al-Ahmady, M Najafi, ... Springer Nature, 2022 | | 2022 |
Investigating the contribution of Immunoresponsive gene 1 (Irg1) to macrophage functions and its relevance to disease L Sanderson PhD Thesis-University of Auckland, 2015 | | 2015 |