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Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation T Visnes, A Cázares-Körner, W Hao, O Wallner, G Masuyer, O Loseva, ... Science 362 (6416), 834-839, 2018 | 200 | 2018 |
UV degradation of natural and synthetic microfibers causes fragmentation and release of polymer degradation products and chemical additives L Sørensen, AS Groven, IA Hovsbakken, O Del Puerto, DF Krause, ... Science of the Total Environment 755, 143170, 2021 | 194 | 2021 |
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Uracil accumulation and mutagenesis dominated by cytosine deamination in CpG dinucleotides in mice lacking UNG and SMUG1 L Alsøe, A Sarno, S Carracedo, D Domanska, F Dingler, L Lirussi, ... Scientific reports 7 (1), 7199, 2017 | 67 | 2017 |
A robust, sensitive assay for genomic uracil determination by LC/MS/MS reveals lower levels than previously reported A Galashevskaya, A Sarno, CB Vågbø, PA Aas, L Hagen, G Slupphaug, ... DNA repair 12 (9), 699-706, 2013 | 67 | 2013 |
Modulation of cell metabolic pathways and oxidative stress signaling contribute to acquired melphalan resistance in multiple myeloma cells KA Zub, MML Sousa, A Sarno, A Sharma, A Demirovic, S Rao, C Young, ... PloS one 10 (3), e0119857, 2015 | 64 | 2015 |
Uracil-DNA glycosylase in base excision repair and adaptive immunity: species differences between man and mouse B Doseth, T Visnes, A Wallenius, I Ericsson, A Sarno, HS Pettersen, ... Journal of Biological Chemistry 286 (19), 16669-16680, 2011 | 61 | 2011 |
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Targeting OGG1 arrests cancer cell proliferation by inducing replication stress T Visnes, C Benítez-Buelga, A Cázares-Körner, K Sanjiv, BMF Hanna, ... Nucleic acids research 48 (21), 12234-12251, 2020 | 46 | 2020 |
dUTPase inhibition augments replication defects of 5-Fluorouracil A Hagenkort, CBJ Paulin, M Desroses, A Sarno, E Wiita, O Mortusewicz, ... Oncotarget 8 (14), 23713, 2017 | 42 | 2017 |
Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress N Bonagas, NMS Gustafsson, M Henriksson, P Marttila, R Gustafsson, ... Nature cancer 3 (2), 156-172, 2022 | 40 | 2022 |
Normal development of mice lacking PAXX, the paralogue of XRCC 4 and XLF R Gago‐Fuentes, M Xing, S Sæterstad, A Sarno, A Dewan, C Beck, ... FEBS Open Bio 8 (3), 426-434, 2018 | 37 | 2018 |
An inverse switch in DNA base excision and strand break repair contributes to melphalan resistance in multiple myeloma cells MML Sousa, KA Zub, PA Aas, A Hanssen-Bauer, A Demirovic, A Sarno, ... PLoS One 8 (2), e55493, 2013 | 33 | 2013 |
Uracil–DNA glycosylase UNG1 isoform variant supports class switch recombination and repairs nuclear genomic uracil A Sarno, M Lundbæk, NB Liabakk, PA Aas, R Mjelle, L Hagen, ... Nucleic acids research 47 (9), 4569-4585, 2019 | 32 | 2019 |
High‐throughput detection of nuclear factor‐kappaB activity using a sensitive oligo‐based chemiluminescent enzyme‐linked immunosorbent assay N Bhattacharya, A Sarno, IS Idler, M Führer, T Zenz, H Döhner, ... International Journal of Cancer 127 (2), 404-411, 2010 | 32 | 2010 |
Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function M Michel, C Benitez-Buelga, PA Calvo, BMF Hanna, O Mortusewicz, ... Science 376 (6600), 1471-1476, 2022 | 29 | 2022 |
MutT homologue 1 (MTH1) catalyzes the hydrolysis of mutagenic O6-methyl-dGTP AS Jemth, R Gustafsson, L Bräutigam, L Henriksson, KSA Vallin, A Sarno, ... Nucleic acids research 46 (20), 10888-10904, 2018 | 27 | 2018 |
Generation of a mouse model lacking the non-homologous end-joining factor Mri/Cyren S Castañeda-Zegarra, C Huse, Ø Røsand, A Sarno, M Xing, ... Biomolecules 9 (12), 798, 2019 | 23 | 2019 |
Sustainable resource production for manufacturing bioactives from micro‐and macroalgae: Examples from harvesting and cultivation in the Nordic region MS Chauton, S Forbord, S Mäkinen, A Sarno, R Slizyte, R Mozuraityte, ... Physiologia Plantarum 173 (2), 495-506, 2021 | 22 | 2021 |